Product name: β-NADPH
Other name:β-NADPH|beta-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt hydrate
Synonym：beta-NADPH; 2′-NADPH hydrate; Coenzyme II reduced tetrasodium salt; Dihydronicotinamide adenine dinucleotide phosphate tetrasodium salt; NADPH Na4; TPNH2 Na4; Triphosphopyridine nucleotide reduced tetrasodium salt
CAS No:2646-71-1
EINECS Number：220-163-3
Purity:≥98%
Storage Temperature: -20°C
Appearance: White to yellow powder
Product Description: β-NADPH (β-Nicotinamide Adenine Dinucleotide Phosphate, Reduced Form Tetrasodium Salt)
CAS Number: 2646-71-1
Molecular Formula: C21H26N7Na4O17P3
Molecular Weight: 833.35
Purity: ≥97% (HPLC)
Appearance: White to off-white powder
Solubility: Freely soluble in water (50 mg/mL)
Key Features
- High Purity & Stability
- Synthetically derived with ≥97% purity, ensuring reliable performance in sensitive biochemical assays .
- Stable at -20°C when stored dry and protected from light; pre-prepared solutions can be aliquoted and stored at -20°C for 1-2 months .
- Broad Applications
- Electron Donor: Serves as a cofactor for oxidoreductases, including nitric oxide synthase and thioredoxin reductase .
- Biosynthesis: Critical for lipid, cholesterol, and nucleotide synthesis via reductive reactions .
- Antioxidant Defense: Protects cells from reactive oxygen species (ROS) by maintaining reduced glutathione levels .
- Diagnostic Reagents: Used in enzymatic assays for clinical research and pharmaceutical development .
- Optical Properties
- UV absorption peaks at 260 nm (ε = 15.0 × 10³ L·mol⁻¹·cm⁻¹) and 340 nm (ε = 6.3 × 10³ L·mol⁻¹·cm⁻¹), ideal for spectrophotometric quantification .
Storage & Handling
- Storage:
- Short-term: 2–8°C in airtight, light-protected containers .
- Long-term: -20°C in desiccated conditions; avoid freeze-thaw cycles .
- Preparation:
- Reconstitute in alkaline buffers (e.g., 10 mM NaOH) for optimal stability; acidic solutions degrade NADPH rapidly .
- Centrifuge lyophilized powder at 2,000–10,000×g before use to ensure homogeneity .
Safety & Compliance
- Intended Use: For research purposes only. Not for diagnostic, therapeutic, or human consumption .
- Safety Precautions:
- Wear lab coats, gloves, and eye protection during handling .
- Non-hazardous under standard transport regulations (UN NONH classification) .
Why Choose Our β-NADPH?
- Global Standards: Produced under FSSC22000 and FDA-compliant quality control systems .
- Technical Support: Backed by collaborations with leading institutions (e.g., Harvard University, CAS) for cutting-edge applications .
- Custom Packaging: Available in 10 mg to 1 g quantities to suit diverse experimental needs .
Keywords: β-NADPH, Coenzyme II reduced, CAS 2646-71-1, electron donor, oxidoreductase cofactor, NADPH tetrasodium salt
