1-(1-Adamantylcarbonyl) Proline

Short Description:

1- (adamantane-1-carbonyl) -pyrrolidine-2-carboxylic acid, also known as ACA, CAS number 35084-48-1, white or off-white powder, is a nitrogen-containing organic substance, used in medicine body, a nw nootropics medicine at present. 1-(1-Adamantylcarbonyl) proline is a phenylalanine derivative, also known as adamantylproline or Ad-Pro. It is mainly used as a catalyst or chiral resolution reagent in organic synthesis

1-(1-Adamantylcarbonyl) proline is a phenylalanine derivative, also known as adamantylproline or Ad-Pro. Mainly used as catalyst or chiral resolution reagent in organic synthesis. Studies have shown that 1-(1-Adamantylcarbonyl) proline can catalyze asymmetric nucleophilic addition reactions, such as the reaction of aldehydes and alkylene azides, the reaction of aldehydes and sulfuryl folate, the reaction of aldehydes and nitro Methane reactions, etc. Among these reactions, this catalyst has the strongest addition activity toward alkylene azides.  1-(1-Adamantylcarbonyl) proline can also catalyze asymmetric amination reactions.  1-(1-Adamantylcarbonyl) proline can also be used as a chiral catalyst to catalyze asymmetric alcoholization. For example, it can react alcohols with aldehydes or ketones to yield the corresponding aldol or hydroxyketone products. 1-(1-Adamantylcarbonyl) proline, as a chiral organic compound, has excellent catalytic activity.


  • FOB Price: US 5 - 2000 / KG
  • Min.Order Quantity: 1 KG
  • Supply Ability: 10000 KG/per Month
  • Port: Shanghai /Beijing
  • Payment Terms: L/C,D/A,D/P,T/T,O/A
  • Shipping Terms: By sea/By Air/By Courier
  • Product Detail

    Product Tags

    Product Name:1-(1-Adamantylcarbonyl) Proline

    Other Name:

    1-(1-ADAMANTYLCARBONYL)PYRROLIDINE-2-CARBOXYLIC ACID;

    1-(ADAMANTANE-1-CARBONYL)-PYRROLIDINE-2-CARBOXYLIC ACID;

    1-(1-Adamantylcarbonyl)proline;L-Proline, 1-(tricyclo[3.3.1.13,7]dec-1-ylcarbonyl)-

    CAS No:35084-48-1

    Specifications: 98.0%

    Colour: white powder with characteristic odor and taste

    GMO Status:GMO Free

    Packing: in 25kgs fiber drums

    Storage:Keep container unopened in cool, dry place,Keep away from strong light

    Shelf Life:24 months from date of production

    Product Description: 1-(1-Adamantylcarbonyl) Proline (CAS 35084-48-1)

    Product Name: 1-(1-Adamantylcarbonyl) Proline
    Synonyms: 1-(Adamantane-1-carbonyl)pyrrolidine-2-carboxylic acid; 1-(1-Adamantylcarbonyl)pyrrolidine-2-carboxylic acid
    CAS Number: 35084-48-1
    Molecular Formula: C₁₆H₂₃NO₃
    Molecular Weight: 277.36 g/mol
    Appearance: White crystalline powder
    Purity: ≥98% (HPLC confirmed)
    Solubility: >41.6 μg/mL (suitable for laboratory and industrial applications)

    Key Applications

    1. Neurological Research: Supports cognitive enhancement, neuronal repair, and brain health. Used in studies targeting neuroprotection and neuroregeneration.
    2. Pharmaceutical Intermediates: Serves as a critical building block in synthesizing bioactive compounds, such as triazoline derivatives and piperazine-based drug candidates.
    3. Nootropic Formulations: Incorporated into supplements for memory enhancement and mental clarity.

    Packaging & Storage

    • Packaging: Available in 25 kg/drum (customizable for bulk orders).
    • Storage: Store in airtight containers at room temperature, protected from light, moisture, and heat.

    Safety & Compliance

    • Hazard Classification: Acute toxicity (oral, dermal, inhalation). Handle with PPE (gloves, goggles) and ensure adequate ventilation.
    • Regulatory Compliance: Meets standards for laboratory and industrial use. Not for medicinal or household applications.

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    • Quality Assurance: Rigorous QC protocols ensure high-purity products.

    Keywords

    1-(1-Adamantylcarbonyl) Proline, CAS 35084-48-1, neuroprotective agent, pharmaceutical intermediate, high-purity powder, bulk chemical supplier, cognitive enhancer, neurological research.


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