Amygdalin Product Description
1. Product Overview
Amygdalin (CAS No. 29883-15-6) is a naturally occurring cyanogenic glycoside extracted from the kernels of Prunus species, including apricots, almonds, and peaches . With the molecular formula C₂₀H₂₇NO₁₁ and a molecular weight of 457.43 g/mol, it exists as a white crystalline powder, soluble in water and hot alcohol . This compound has garnered attention for its potential applications in biochemical and pharmacological research, particularly in studies related to cancer mechanisms, anti-inflammatory effects, and cell cycle modulation .
2. Key Features
- High Purity: ≥98% (HPLC verified) .
- Stability: Stable at room temperature when stored in a dry, ventilated environment .
- Optimized Extraction: Utilizes orthogonal design to ensure optimal temperature and pressure control, preserving chemical integrity and potency .
- Safety Compliance: Meets standards for laboratory use, with detailed safety protocols provided .
3. Applications in Research
- Anticancer Studies: Investigated for its role in inducing apoptosis, modulating EMT-related proteins (e.g., E-cadherin), and arresting cell cycle progression in cancer cells .
- Anti-Inflammatory & Analgesic Effects: Demonstrated dose-dependent reduction in inflammatory pain in preclinical models .
- Biochemical Substrate: Used as a substrate for enzymes like β-glucosidase and emulsin .
4. Quality Control
- Source Selection: Kernels are harvested at optimal maturity to maximize amygdalin content, with bitter kernels containing significantly higher levels (up to 44.6 mg/g) compared to sweet varieties .
- Purification Process: Multi-step crystallization ensures a pure, contaminant-free product, validated against the Merck Index .
- Batch Consistency: Rigorous testing for microbial contamination and chemical stability .
5. Safety & Regulatory Information
- Toxicity Warning: Oral ingestion releases cyanide via enzymatic hydrolysis, posing risks of poisoning. Use strictly in controlled laboratory settings .
- Protective Measures:Regulatory Status: Banned for therapeutic use in the U.S. and Europe due to unproven efficacy and safety concerns. Sold exclusively for research purposes .
- Personal Protective Equipment (PPE): Nitrile gloves (≥0.11 mm thickness), safety goggles, and P2 respirators in dusty environments .
- First Aid: Immediate rinsing for skin/eye contact and medical consultation for accidental ingestion .
6. Ordering & Support
- Packaging Options: Available in 10 mg and 20 mg vials, with custom quantities upon request .
- Documentation: Compliant SDS, COA, and technical data sheets provided .
- Global Shipping: Stocked for immediate delivery, adhering to international hazardous material regulations .
Keywords
Amygdalin CAS 29883-15-6, High Purity Amygdalin Powder, Amygdalin for Cancer Research, Apoptosis-Inducing Compound, Laboratory-Grade Cyanogenic Glycoside.
Bitter Apricot Extract amygdalin function:
1.Bitter almond contains amygdalin, amygdalin intestinal microbial enzymes in the body, or can be itself contained in the bitter almond bitter almond bitter almond hydrolysis to produce small amounts of hydrocyanic acid and benzaldehyde, inhibit the respiratory center, to cough, asthma .
2.Anti-inflammatory and analgesic effects.
3. Attending functions lower gas cough and asthma, laxative. For cough, asthma, chest full of phlegm, blood-chun, dry, dry bowel constipation.
4.Lowering blood sugar,Hypolipidemic.
5.Elimination of pigmentation, freckles, dark spots, so as to achieve the effect of beauty.
6.can Inhibit the respiratory center, cough and asthma .
7.can Anti-inflammatory and analgesic effects.
8.can Anti-tumor effect.
9.can Lower blood sugar, hypolipidemic.
10.Elimination of pigmentation, freckles, dark spots, so as to achieve the effect of beauty.
11. Has effect on cough, asthma, chest full of phlegm, blood-chun, dry, dry bowel constipation.
Application:
1.significantly reduced the plaque index and bacterial count.
2. reduced oxidative stress and lowers blood sugar level in body.
3. interferes the life cycle of lice, inhibiting their ability to feed and preventing eggs from hatching.
4. enhances lipid peroxidation in the liver and blood of tumor-bearing models and accompanied by significant decreases in the activities of GSH-dependent antioxidant.
5. immobilizes and kills 100% human spermatozoa at high concentration.
6. lowers the lipid levels especially cholesterol and LDL-cholesterol in body.
7.When in health food field, Bitter Apricot kernel extract is widely used in food additives industry, which can be added into the dairy, beverage health care products, pastries, cold drinks, jelly, bread, milk and so on;
8.When in cosmetic field, Amygdalin is a kind of treatment for anti-skin cancer;
9.Vitamin B17 can also be used in pharmaceutical field.