Product Name:Apple Extract
Latin Name:Malus pumila Mill.
CAS No.: 84082-34-8 60-82-2 4852-22-6
Plant Part Used:Fruit
Assay: Polyphenols:40-80%（UV）Phloridzin: 40-98% (HPLC)Phloretin 40-98%(HPLC)
Colour:brown yellow powder with characteristic odor and taste
GMO Status:GMO Free
Packing: in 25kgs fiber drums
Storage:Keep container unopened in cool, dry place,Keep away from strong light
Shelf Life:24 months from date of production
Apple Extract Phloridzin: Benefits, Applications, and Scientific Insights
Product Overview
Apple Extract Phloridzin is a natural bioactive compound derived primarily from apple trees (Malus domestica), including the bark, leaves, roots, and fruit peels . As a dihydrochalcone flavonoid, it is unique to apples and their wild relatives, making it a signature polyphenol for quality control in apple-derived products like juices and supplements . Its molecular formula is C21H24O10, with a CAS No. 60-81-1, and it is available as a high-purity powder for versatile applications .
Key Health Benefits
- Anti-Diabetic Properties
Phloridzin inhibits sodium-glucose cotransporters (SGLT1 and SGLT2) in the intestines and kidneys, reducing sugar absorption and lowering blood glucose levels. Clinical studies highlight its potential in managing type 2 diabetes and obesity .- Mechanism: Blocks glucose-6-phosphatase enzyme activity, supporting healthy glucose levels .
- Bioavailability: Often formulated as a polymer to enhance absorption, as it hydrolyzes into phloretin in the body .
- Antioxidant and Anti-Aging Effects
Phloridzin combats oxidative stress by trapping reactive glycation agents (MGO/GO) and inhibiting lipid peroxidation. It also boosts paraoxonase, an antioxidant enzyme, by up to 23% .- Anti-Aging: Enhances SOD1/2 and SIRT1 gene expression, protecting cells from oxidative damage .
- Cardiovascular and Metabolic Health
- Reduces triglyceride absorption by blocking pancreatic lipase .
- Exhibits anti-inflammatory effects and supports liver function by modulating insulin-related pathways .
- Antimicrobial and Anticancer Potential
- Its degradation product, phloretin, inhibits microbial growth and fungal infections .
- Apple polyphenols, including phloridzin, show promise in suppressing tumor growth and colorectal cancer risk .
Applications in Industries
- Nutraceuticals: Used in functional foods and supplements targeting diabetes, weight management, and antioxidant support .
- Cosmetics: Incorporated into anti-aging formulations for its skin-protective and glycation-inhibiting properties .
- Pharmaceuticals: Investigated for drug development, particularly SGLT inhibitors and anti-diabetic therapies .
- Food Preservation: Added to inhibit oxidation and microbial spoilage in processed foods .
Quality and Sourcing
- Extraction: Optimized using acetone-mediated methods, yielding concentrations up to 894.6 mg/kg .
- Source: Sourced from organic apples, with higher phloridzin content in russeted peels (e.g., Golden Delicious cultivars) .
- Certification: Compliant with GMP standards, ensuring purity and safety .
Why Choose Our Phloridzin?
- High Purity: ≥98% purity, verified by HPLC .
- Customization: Available in bulk powder, capsules, or liquid extracts for diverse formulations .
- Sustainability: Utilizes apple pomace byproducts, reducing waste .
- Global Shipping: Fast delivery via air/sea, with samples available for testing .
Scientific Backing
Phloridzin’s efficacy is validated by studies from institutions like Cornell University and the Drawa National Park, highlighting its role in apple disease resistance (e.g., Valsa canker) and metabolic health . European dietary studies confirm its safe intake (0.7–7.5 mg/day) through apples and juices .
Keywords : Apple Extract Phloridzin, Natural SGLT Inhibitor, Anti-Diabetic Supplement, Antioxidant Powder, Phloretin Source, Organic Apple Polyphenols
