Product Name:Berberine hydrochloride 97%
Botanical Source:
Part Used:Root
Test method: HPLC
Other name: berberine hcl;berberine hydrochloride;berberine powder;berberine hcl powder;berberine hydrochloride powder
Molecular Formula: C20H18ClNO4
Molecular Weight: 371.81
CAS No.:633-65-8
Color: yellow crystalline powder
GMO Status:GMO Free
Packing: in 25kgs fiber drums
Storage:Keep container unopened in cool, dry place,Keep away from strong light
Shelf Life:24 months from date of production
Berberine Hydrochloride 97% Product Description
Product Overview
Berberine Hydrochloride 97% is a high-purity natural alkaloid extracted from the bark, roots, and stems of plants such as Berberis aristata, Coptis chinensis, and Phellodendron amurense . With a purity level of ≥97% (verified by HPLC and UV-spectrophotometric methods), this compound is widely utilized in pharmaceutical research, nutraceutical development, and biomedical applications . Known for its bright yellow crystalline appearance and bitter taste, it is sparingly soluble in cold water but dissolves well in hot water and methanol .
Key Features
- High Purity: ≥97% (actual tested purity up to 97.5%) with strict quality control via HPLC and UV-spectrophotometry .
- Natural Source: Sustainably extracted from Berberis species and other medicinal plants, ensuring an eco-friendly profile .
- Stability: Store at 2–8°C in airtight, light-resistant packaging to maintain efficacy .
Pharmacological Benefits
Berberine Hydrochloride 97% exhibits diverse pharmacological activities, supported by extensive research:
- Blood Sugar & Lipid Regulation: Enhances AMPK activation, aiding glucose metabolism and cholesterol reduction .
- Antimicrobial Effects: Effective against bacteria (e.g., E. coli, Staphylococcus), viruses, and parasites, particularly in treating gastrointestinal infections .
- Antioxidant & Anti-inflammatory: Scavenges free radicals (e.g., DPPH) and inhibits lipid peroxidation, supporting cellular health .
- Anti-Cancer Potential: Induces apoptosis in cancer cells (e.g., HeLa229) via p53 activation and Bcl-2/COX-2 suppression .
- Neuroprotective & Cardiovascular Benefits: Emerging studies suggest roles in Alzheimer’s disease and anti-arrhythmic effects .
Applications
- Pharmaceuticals: Used in antidiabetic drugs, antimicrobial formulations, and anticancer research .
- Nutraceuticals: Incorporated into dietary supplements for metabolic and cardiovascular health .
- Research: Studied for nanoparticle delivery systems to improve bioavailability .
Quality Assurance
- Purity Testing: Validated via UV-spectrophotometry (422 nm wavelength) and HPLC .
- Safety Compliance: Heavy metals (Pb ≤3 ppm, As ≤2 ppm), microbial limits (total bacteria ≤1000 CFU/g), and solvent residues meet international standards .
- Certifications: GMO-free, vegan-friendly, and produced under ISO-certified facilities .
Packaging & Shipping
- Standard Packaging: 25 kg/bag (customizable upon request) .
- Global Delivery: Shipped via FedEx, DHL, or UPS with temperature-controlled logistics .
Safety & Compliance
- Intended Use: For industrial and research purposes only (e.g., pharmaceuticals, nutraceuticals). Not for direct consumer use .
- Handling Precautions: Wear protective gear; avoid inhalation or direct contact (H315/H319 warnings) .
Keywords: Berberine HCl 97%, Natural Alkaloid, Antimicrobial Agent, Blood Sugar Support, HPLC-Validated, Bulk Supplier
