Product Name:Wogonin Bulk Powder
Botanic Source:Scutellaria baicalensis
CAS No:632-85-9
Other Name:Vogoni，wagonin， Wogonin hydrate, Vogonin Norwogonin 8-methyl ether
Specifications:≥98% HPLC
Colour: Yellow powder with characteristic odor and taste
GMO Status:GMO Free
Packing: in 25kgs fiber drums
Storage:Keep container unopened in cool, dry place,Keep away from strong light
Shelf Life:24 months from date of production
Bulk Wogonin Powder | CAS 632-85-9 | High Purity Natural Flavonoid for Research
Keywords: Bulk Wogonin Powder, Wogonin CAS 632-85-9, Anti-Cancer Flavonoid, Research-Grade Wogonin, Wogonin for Cell Studies
Product Overview
Wogonin is a bioactive O-methylated flavonoid extracted from Scutellaria baicalensis Georgi, widely recognized for its anti-cancer, anti-inflammatory, and antioxidant properties . With CAS number 632-85-9 and molecular formula C₁₆H₁₂O₅, this compound is ideal for in vitro and in vivo research targeting cancer mechanisms, inflammatory pathways, and oxidative stress .
Key Features
- High Purity & Quality Control
- Purity: ≥98% (HPLC verified)
- Solubility: Soluble in DMSO (50 mM stock solution) and ethanol (3 mg/mL)
- Storage: Stable for 3 years at -20°C in powder form; avoid freeze-thaw cycles in solution
- Mechanisms of Action
- Anti-Cancer: Inhibits CDK9/ERK/IL-8 signaling, induces apoptosis in HL-60 leukemia and MDA-MB-231 breast cancer cells .
- Anti-Inflammatory: Blocks COX-2 expression via AP-1 suppression and reduces NFATc1 nuclear translocation .
- Antioxidant: Scavenges superoxide radicals, protecting cells from oxidative damage .
- Research Applications
- Cancer Studies: Suppresses tumor growth in xenograft models and inhibits metastasis .
- Inflammation Models: Attenuates LPS-induced IL-8/MMP-9 production in macrophages .
- Drug Development: Potential candidate for combination therapies targeting PI3K/AKT and Wnt/β-catenin pathways .
Technical Specifications
| Parameter | Details |
|---|---|
| CAS Number | 632-85-9 |
| Molecular Weight | 284.26 g/mol |
| Appearance | Light yellow to green crystalline powder |
| Purity (HPLC) | ≥98% |
| Storage Conditions | -20°C (dry powder), -80°C (solutions) |
| Safety | For research use only. Not for human consumption. |
Why Choose Our Wogonin Powder?
- Third-Party Tested: Independent labs verify identity, purity, and potency (COA available upon request) .
- Global Shipping: Ice-packed delivery from US/EU warehouses, ensuring stability during transit .
- Custom Solutions: Bulk quantities (1g-10kg) and formulation support for specialized experiments
