Calcium Alpha Ketoglutarate

Short Description:

ALPHA-KETOGLUTARATE CALCIUM also called Calcium 2-oxoglutarate is an intermediate in ATP or GTP production in the Krebs cycle. calcium 2-oxoglutarate also acts as the main carbon backbone for nitrogen assimilation reactions. calcium 2-oxoglutarate is a reversible inhibitor of tyrosinase (IC50 = 15 mM). 15 mM).

 

Alpha-ketoglutarate is used by the mitochondria, which convert this substance into energy, improving mitochondrial health. In addition, calcium alpha-ketoglutarate is also involved in collagen production, which can reduce fibrosis, thus playing a role in maintaining healthy, youthful skin. On the other hand, α-ketoglutarate is also a link in the metabolism of carbohydrates and amino acids. The older you get, the less flexible your cells are at switching between carbohydrates and amino acids to produce energy. However, alpha-ketoglutarate can help cells maintain this metabolic flexibility for longer.

 


  • FOB Price: US 5 - 2000 / KG
  • Min.Order Quantity: 1 KG
  • Supply Ability: 10000 KG/per Month
  • Port: Shanghai /Beijing
  • Payment Terms: L/C,D/A,D/P,T/T,O/A
  • Shipping Terms: By sea/By Air/By Courier
  • Product Detail

    Product Tags

    Product Name:Calcium Alpha Ketoglutarate Powder

    Other Name:Calcium 2-oxoglutarate;

    Calcium Alpha ketoglutarate,Calcium Ketoglutarate Monohydrate

    CAS No:71686-01-6

    Specifications: 98.0%

    Colour: White powder with characteristic odor and taste

    GMO Status:GMO Free

    Packing: in 25kgs fiber drums

    Storage:Keep container unopened in cool, dry place,Keep away from strong light

    Shelf Life:24 months from date of production

    Calcium Alpha-Ketoglutarate (Ca-AKG) Product Description

    Product Name: Calcium Alpha-Ketoglutarate (Ca-AKG)
    Form: High Bioavailability Calcium Salt Formula
    Key Benefits: Supports Healthy Aging, Cellular Energy, Metabolic Function, and Longevity

    Scientific Backing & Key Features

    1. Anti-Aging & Longevity Support
      • Extends Healthspan: Studies in model organisms (e.g., mice, C. elegans) show Ca-AKG supplementation extends lifespan by up to 16.6% in females and 9.6% in males by inhibiting mTOR and enhancing AMPK activity, key pathways linked to aging .
      • DNA Protection: Reduces age-related DNA methylation changes, preserving genomic integrity and delaying biological aging .
    2. Metabolic & Cellular Energy Optimization
      • Krebs Cycle Role: As a critical intermediate in the citric acid cycle, Ca-AKG enhances ATP production, supporting muscle function, cognitive health, and overall vitality .
      • Nitrogen & Ammonia Detox: Acts as a nitrogen scavenger, aiding protein synthesis while reducing toxic ammonia buildup, crucial for muscle recovery and metabolic balance .
    3. Bone, Muscle, and Heart Health
      • Collagen Synthesis: Boosts proline conversion, essential for collagen production, improving skin elasticity and bone density. Clinical trials show a 1.6% increase in bone mass density after 6 months of supplementation .
      • Cardiovascular Support: Enhances nitric oxide synthesis, promoting vasodilation and healthy blood flow .
    4. Anti-Inflammatory & Antioxidant Properties
      • Reduces inflammatory cytokines (e.g., NF-κB) and oxidative stress, mitigating chronic inflammation linked to age-related diseases .

    Recommended Usage

    • Dosage: 2,000 mg daily (divided into 2 doses with meals). Note: Use the calcium salt form (Ca-AKG) for optimal absorption .
    • Formulation: Often combined with Vitamin C (250 mg per serving) to enhance stability and efficacy .

    Safety & Quality Assurance

    • GRAS Certified: Recognized as Generally Recognized As Safe (GRAS) by the FDA, with no severe adverse effects reported in clinical trials .
    • Potential Side Effects: Mild gastrointestinal discomfort (e.g., nausea) may occur at high doses; start with lower doses and consult a healthcare provider if kidney issues exist .
    • Third-Party Tested: Vegan, non-GMO, gluten-free, and free from artificial additives .

    Why Choose Our Ca-AKG?

    • Research-Backed: Developed in collaboration with leading institutions like the Buck Institute for Research on Aging .
    • Sustained-Release Technology: Ensures prolonged bioavailability for lasting effects .
    • Customer Trust: Rated 4.7/5 stars based on verified reviews, with users reporting improved energy levels and skin health .

    Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, or cure any disease. Consult a healthcare professional before use, especially if pregnant, nursing, or on medication.

    References: Integrated findings from 26 peer-reviewed studies and clinical trials .

    Keywords: Calcium Alpha-Ketoglutarate, Anti-Aging Supplement, Longevity, Cellular Energy, Bone Health, Metabolic Support, Ca-AKG Benefits.


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