Product Name:Calcium L-Threonate
Other Name:L-Threonic Acid Calcium;L-threonic acid hemicalciumsalz;L-Threonic acid calcium salt ;(2R,3S)-2,3,4-Trihydroxybutyric acid hemicalcium salt
CAS No:70753-61-6
Specifications: 98.0%
Colour:White fine powder with characteristic odor and taste
GMO Status:GMO Free
Packing: in 25kgs fiber drums
Storage:Keep container unopened in cool, dry place,Keep away from strong light
Shelf Life:24 months from date of production
Calcium L-Threonate: A High Bioavailability Calcium Supplement for Bone Strength and Cognitive Support
Product Overview
Calcium L-Threonate (CAS 70753-61-6) is an advanced calcium supplement derived from vitamin C metabolites, offering superior bioavailability and dual benefits for bone health and cognitive function. Its unique molecular structure—a moderate-sized chelate complex with balanced water and lipid solubility—enables direct intestinal absorption without relying on traditional calcium transport pathways, achieving a bioavailability of 26.49% as demonstrated in clinical studies .
Key Benefits
- Enhanced Bone Density & Osteoporosis Prevention
- Stimulates bone formation and inhibits osteoclast-mediated bone resorption, making it effective for treating osteoporosis and bone loss .
- Studies show its inhibitory effect on bone resorption is comparable to 17β-estradiol at higher concentrations, supporting its role as a bone-strengthening agent .
- Cognitive Support & Neuronal Health
- Facilitates calcium-dependent neurotransmitter release and maintains neuronal membrane potential, critical for memory encoding and brain function .
- Unlike conventional calcium forms, L-Threonate may cross the blood-brain barrier, supporting neural efficiency (analogous mechanism to Magnesium L-Threonate).
- Superior Absorption with Minimal Side Effects
- Clinically proven to be well-tolerated, with no serious adverse events reported even at doses up to 4,050 mg/day .
- Avoids common calcium-related issues like constipation due to its efficient absorption pathway .
Scientific Validation
- Bioavailability: A double-label isotope study confirmed 26.49 ± 9.39% bioavailability in healthy subjects, with rapid absorption and no systemic accumulation .
- Safety: Approved by the European Food Safety Authority (EFSA) as a safe calcium source, with no toxicity concerns at proposed daily intakes (200–400 mg calcium) .
- Mechanism: Acts as a metabolite of ascorbic acid, enhancing calcium uptake in cells and potentially synergizing with vitamin C for antioxidant benefits .
Usage & Safety Guidelines
- Recommended Dose: 200–400 mg daily, adjustable to individual needs (higher doses may be required for osteoporosis) .
- Precautions:Contraindications: Do not supplement if blood calcium levels are already sufficient to avoid potential neurotoxicity .
- Avoid inhalation or direct contact with eyes/skin; use protective equipment during handling .
- Store in a cool, dry place (4°C for long-term stability) .
Certifications & Compliance
- EFSA Compliance: Recognized as a bioavailable calcium source with no safety risks at recommended doses .
- GMP & FDA Standards: Produced in certified facilities, ensuring >98% purity and rigorous quality control .
Ordering Information
- Packaging: Available in powder (1g–25g) and tablet forms.
- CAS Number: 70753-61-6 | Molecular Formula: C₈H₁₄CaO₁₀ | Molecular Weight: 310.27 .
- Global Shipping: Compliant with harmonized tariff codes (e.g., 29181998900) for seamless international delivery .
Why Choose Calcium L-Threonate?
Unlike traditional calcium supplements (e.g., carbonate or citrate), Calcium L-Threonate combines bone-strengthening efficacy with cognitive support, backed by peer-reviewed research and regulatory approvals. Its high tolerability and absorption efficiency make it ideal for long-term use in populations at risk of osteoporosis or cognitive decline.
Keywords: Calcium supplement, osteoporosis treatment, cognitive health, bioavailability, EFSA-approved, L-Threonate mechanism.
