Product Name:Citicoline Sodium powder
CAS NO.:33818-15-4
Specification:99%
Appearance: Fine white to off-white crystal Powder
Origin: China
GMO Status:GMO Free
Packing: in 25kgs fiber drums
Storage:Keep container unopened in cool, dry place,Keep away from strong light
Shelf Life:24 months from date of production
Citicoline Sodium Bulk Powder: High-Purity Neuroprotective Agent for Cognitive & Ocular Health
Product Overview
Citicoline Sodium (CAS 33818-15-4), also known as CDP-Choline sodium, is a naturally occurring endogenous compound critical for phospholipid synthesis in cellular membranes. With a molecular formula of C₁₄H₂₅N₄NaO₁₁P₂ and molecular weight 510.31, this white crystalline powder is highly soluble in water (200 mg/mL) and meets USP 41 standards for purity (98.0%-102.0%) . Sourced from premium manufacturers like Kyowa Hakko Bio, it is widely utilized in pharmaceuticals, dietary supplements, and ophthalmic solutions .
Key Benefits & Applications
- Neuroprotection & Cognitive Enhancement
- Mechanism: Citicoline Sodium hydrolyzes into cytidine and choline, precursors for phosphatidylcholine synthesis—essential for neuronal membrane repair and neurotransmitter regulation .
- Clinical Applications:
- Cognitive Decline: Shown to improve memory, focus, and learning in Alzheimer’s and dementia models .
- Stroke & Brain Injury: Enhances post-stroke recovery by reducing oxidative stress and promoting neural repair .
- Traumatic Brain Injury (TBI): While some trials indicate no significant improvement in severe TBI, it remains approved in 59 countries for TBI support due to its neurorepair potential .
- Ocular Health
- Glaucoma & AMD: Topical 2% citicoline ophthalmic solutions (e.g., OMK1®-LF) improve visual acuity and optic nerve function, with vitreous concentrations reaching 406.72 μg/mL in clinical studies .
- Retinal Protection: Reduces oxidative damage in age-related macular degeneration (AMD) .
- Industrial & Cosmetic Uses
- Skincare: Enhances skin hydration and elasticity in creams/lotions .
- Supplements: Available in capsules (250-1000 mg), tablets, and oral solutions (500 mg/day) for cognitive support .
Product Specifications
- Purity: ≥98% (HPLC-verified) .
- Storage:
- Powder: Stable for 3 years at -20°C.
- Solutions: Store at -80°C for 1 year.
- Packaging: 25 mg, 100 mg, 200 mg bulk powder options; customizable OEM solutions .
- Safety: Well-tolerated with minimal side effects; contraindicated in shellfish allergy patients .
Quality Assurance
- Analytical Methods: Validated HPLC using C18 columns (L1 filler) with UV detection (262 nm), ensuring compliance with USP and EMA standards .
- Certifications: Listed in WHO ATC, FDA Unique Ingredient Identifier (536BQ2JVC7), and EU Novel Food approvals (2014/423/EU) .
Why Choose Our Citicoline Sodium?
- Global Compliance: Meets USP, EP, and ICH guidelines for pharmaceutical use.
- Bulk Supply: Annual production capacity of 200 tons, ensuring scalable and cost-effective solutions .
- Research-Backed: Supported by 50+ clinical studies on neuroprotection and ocular efficacy .
Contact Us Today
For pricing, COA, or custom formulations, reach out to our team. Elevate your product line with Citicoline Sodium—trusted by leading pharmaceutical and nutraceutical brands worldwide.
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