Alpha-GPC (Choline Alfoscerate)

Short Description:

Alpha GPC, is a key brain cell membrane phospholipid and cholinergic precursor. It is a source of choline for the synthesis of the neurotransmitter acetylcholine, with a greater ability to penetrate the blood-brain barrier than conventional choline sources. Choline alfoscerate is an important neurotransmitter and phospholipid precursor providing support for age-related decline in cognitive function, memory, and cerebrovascular health.In Europe,it is prescribed to treat  Alzheimer’s disease. In the United States, it is an over-the-counter nootropic dietary choline supplement intended to improve memory and cognitive function, as well as encourage muscle building.


  • FOB Price: US 5 - 2000 / KG
  • Min.Order Quantity: 1 KG
  • Supply Ability: 10000 KG/per Month
  • Port: Shanghai /Beijing
  • Payment Terms: L/C,D/A,D/P,T/T,O/A
  • Shipping Terms: By sea/By Air/By Courier
  • E-mail:: info@trbextract.com
  • Product Detail

    Product Tags

    Product Name:Choline Alfoscerate/Alpha GPC

    Other name: Alpha GPC, α-GPC, Choline Alfoscerate, L-α GPC, GPC Choline, l-alpha-glycerylphosphorylcholine, Choline Glycerophosphate, CDP-choline, Glycerophosphocholine, Glicerofosfato de Colina, Glycerophosphate De Choline.

    Assay:50% ~99%

    Specification:Alpha GPC 50 powder  25kg/Drum
    Alpha GPC 50% granule  25kg/Drum
    Alpha GPC liquid 85%  25kg/Drum
    Alpha GPC powder 99%  1kg/Bag  25kg/Drum
    Alpha-GPC softgel/Alpha-GPC capsule/Alpha-GPC tablet

    CAS No.:  28319-77-9

    Formula:  C8H20NO6P

    Mol. Mass:  257.22

    Appearance:  white to off-white powder or transparent liquid.

    Alpha-GPC (Choline Alfoscerate) Product Description
    Enhance Cognitive Performance & Brain Health

    Product Overview

    Alpha-GPC (L-alpha-glycerylphosphorylcholine), also known as Choline Alfoscerate, is a premium phospholipid-derived choline supplement. Renowned for its high bioavailability and ability to cross the blood-brain barrier, it serves as a potent precursor to acetylcholine—a critical neurotransmitter for memory, learning, and muscle function. With a choline content of 41% by weight, Alpha-GPC is ideal for supporting brain health, cognitive enhancement, and age-related neurological support.

    Key Benefits

    1. Cognitive Enhancement:
      • Boosts acetylcholine synthesis, improving memory, focus, and mental clarity.
      • Clinically shown to benefit individuals with age-related cognitive decline, vascular dementia, and Alzheimer’s disease.
    2. Neuroprotective Effects:
      • Restores neuronal membrane fluidity and reverses structural brain changes in the hippocampus and frontal cortex.
      • Enhances nerve growth factor (NGF) receptor activity, promoting neuronal repair.
    3. Growth Hormone Support:
      • Stimulates human growth hormone (hGH) release, aiding muscle recovery and anti-aging benefits.
    4. Physical Performance:
      • Supports neuromuscular function and endurance, making it popular among athletes.

    Mechanism of Action

    Alpha-GPC is rapidly absorbed and metabolized into choline and glycerophosphate. Choline directly contributes to acetylcholine synthesis, while glycerophosphate supports phospholipid membrane integrity. Unlike other choline sources, Alpha-GPC’s phospholipid structure allows uncharged passage through the blood-brain barrier, ensuring efficient delivery to brain tissues.

    Clinical Evidence

    • Vascular Dementia: A controlled trial demonstrated significant cognitive improvement in patients taking Alpha-GPC compared to placebo.
    • Alzheimer’s Disease: Outperformed acetyl-L-carnitine (ALCAR) in slowing cognitive decline.
    • Aging Brain: Meta-analyses confirm its efficacy in enhancing memory and attention in elderly populations.

    Recommended Usage

    • Dosage: 250–600 mg daily, depending on needs. Clinical studies often use 700 mg/day for optimal results.
    • Form: Capsules or powder for easy absorption.
    • Best Taken: With meals to enhance bioavailability.

    Safety & Quality

    • GRAS Status: Generally Recognized As Safe (GRAS) by the FDA.
    • Side Effects: Rare and mild (e.g., headaches, gastrointestinal discomfort). Avoid combining with anticoagulants or other cholinergic drugs.
    • Certifications: Produced in GMP-certified facilities, ensuring purity and potency.

    Why Choose Our Alpha-GPC?

    • High Purity: ≥98% pharmaceutical-grade Alpha-GPC, derived from non-GMO sources.
    • Trusted Brand: Manufactured by AOR, a leader in nutraceutical innovation.
    • Research-Backed: Supported by over 30 clinical studies and meta-analyses.

    Keywords include Alpha-GPC benefitscholine supplement for brain healthcognitive enhancer, and natural nootropic.

    References:

    • Product specifications and clinical data cited from peer-reviewed studies.
    • Safety profiles aligned with FDA and GRAS guidelines.

    Discover the power of Alpha-GPC—your brain’s best ally for peak performance and longevity.

     

     

     

     


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