Product Name:Dehydrocholic Acid
CAS No:81-23-2
Assay:98.0% Min
Colour:White to off-white powder with characteristic odor and taste
GMO Status:GMO Free
Packing: in 25kgs fiber drums
Storage:Keep container unopened in cool, dry place,Keep away from strong light
Shelf Life:24 months from date of production
Dehydrocholic Acid: Functions, Applications, and Pharmaceutical Benefits
1. Product Overview
Dehydrocholic Acid (CAS 81-23-2), a synthetic triketo bile acid derivative, is USP-certified for pharmaceutical and research use . As a choleretic agent, it enhances bile secretion and fluidity, making it critical in managing biliary disorders.
2. Key Benefits & Mechanisms
✅ Stimulates Bile Production
- Increases bile volume by 270% in clinical models through hydrocholeretic action .
- Reduces biliary cholesterol and phospholipid levels by 64-94%, improving bile composition .
✅ Promotes Biliary Drainage
- Facilitates bile flow to alleviate bile duct obstruction and cholestasis .
- Metabolized into bioactive hydroxy-keto derivatives for sustained effects .
✅ Research Applications
- Used in pharmacokinetic studies of bile acid metabolism .
- Standard reference material for analytical testing (USP grade) .
3. Clinical & Industrial Applications
3.1 Therapeutic Uses
- Biliary Stasis Treatment: First-line option for post-surgical bile flow restoration .
- Cholelithiasis Adjunct: Enhances dissolution of cholesterol-rich gallstones when combined with ursodeoxycholic acid .
- Diagnostic Aid: Historical use in “Decholin®” for hepatic function testing .
3.2 Pharmaceutical Formulations
- Injectable solutions (pH 9-11) meeting USP standards for hospital use .
- Oral tablets compounded with alkaline buffers to improve solubility .
4. Safety & Handling
Professional Use Only
- Classified as Acute Toxicity Category 4 (Oral) and Skin Irritant Category 2 .
- Requires PPE (gloves, goggles) and handling in ventilated facilities .
Download full SDS from MedChemExpress .
5. Packaging & Supply
- Available in research (1mg-100mg) and bulk quantities (25kg/50kg fiber drums) .
- Custom synthesis and purity levels (≥95%) upon request .
6. Why Choose Our Product?
- USP-verified quality with batch-specific COA .
- Supported by 50+ years of clinical research (e.g., Soloway et al. 1973 ).
- Globally compliant: FDA-recognized and EU GMP-certified manufacturing
