Product Name:Apple Extract
Latin Name:Malus pumila Mill.
CAS No.: 84082-34-8 60-82-2 4852-22-6
Plant Part Used:Fruit
Assay: Polyphenols:40-80%（UV）Phloridzin: 40-98% (HPLC)Phloretin 40-98%(HPLC)
Colour:brown yellow powder with characteristic odor and taste
GMO Status:GMO Free
Packing: in 25kgs fiber drums
Storage:Keep container unopened in cool, dry place,Keep away from strong light
Shelf Life:24 months from date of production
Apple Extract Phloridzin: Natural Support for Glucose Metabolism and Antioxidant Protection
Product Overview
Phloridzin, a unique polyphenolic compound found exclusively in apples (Malus domestica), is extracted from organic, high-quality apple cultivars using advanced acetone-mediated or ethanol-based methods to ensure optimal purity and potency . This natural ingredient is renowned for its multifaceted health benefits, including glucose regulation, anti-glycation effects, and antioxidant support, making it ideal for nutraceuticals, functional foods, and skincare formulations.
Key Benefits
- Glucose Metabolism Support
Phloridzin inhibits sodium-glucose cotransporters (SGLT1 and SGLT2), reducing intestinal glucose absorption and renal glucose reabsorption. This mechanism helps maintain healthy blood sugar levels within the normal range, particularly beneficial for metabolic health . Clinical studies highlight its role in managing diabetic and obesity-related conditions by mimicking the action of pharmaceutical SGLT2 inhibitors, with a Ki value of 39 nM for SGLT2 . - Anti-Glycation & Antioxidant Properties
Phloridzin traps reactive methylglyoxal (MGO) and glyoxal (GO), preventing the formation of advanced glycation end products (AGEs) linked to aging and chronic diseases . It also boosts the antioxidant enzyme paraoxonase by up to 23%, reducing lipid peroxidation and inflammation . - Cardiovascular and Cancer Prevention
Regular apple polyphenol intake correlates with reduced risks of cardiovascular disease and certain cancers (e.g., colorectal, breast). Phloridzin synergizes with apple fiber to modulate bile acid metabolism, further supporting colorectal health . - Skin Health
Used in cosmetics, phloridzin enhances antioxidant defenses without stimulating melanogenesis at recommended concentrations, ensuring safety for anti-aging formulations .
Applications
- Dietary Supplements: Capsules (e.g., 600 mg AppleWise® extracts) for metabolic and antioxidant support .
- Functional Foods: Added to beverages, juices, and snacks to enhance nutritional profiles .
- Skincare: Integrated into serums and creams to combat oxidative stress and glycation-induced skin damage .
Scientific Validation
- Source Optimization: Phloridzin content varies by apple cultivar, with russeted varieties (e.g., Golden Russet) containing up to 978.8 µg/g in peels—significantly higher than standard cultivars .
- Extraction Efficiency: Advanced methods yield concentrations of 314.7–894.6 mg/kg, ensuring consistent quality .
- Safety: GRAS (Generally Recognized As Safe) status for food and cosmetic use, with no adverse effects reported at therapeutic doses .
Why Choose Our Phloridzin?
- Organic Sourcing: Derived from certified organic apples, free from pesticides and heavy metals .
- Third-Party Tested: Guaranteed purity (>95% polyphenols) and compliance with international standards .
- Customizable Formats: Available as powder (43.6 mg/mL in ethanol), capsules, or liquid extracts for diverse formulations .
Keywords
Apple polyphenols, Phloridzin benefits, natural SGLT2 inhibitor, anti-glycation agent, organic apple extract, glucose metabolism support, skincare antioxidants.
