Product Name:Genistein 98%
[Active ingredient]Genistein
[Latin Name]Lycium barbarum L.
[ Biogenic origin] Wild in central and southern China
[CAS NO]446-72-0
[ Specification]98%
[ Test Method] by HPLC
[ Molecular formula]C15H10O5
[Molecular Weight]270.24
GMO Status:GMO Free
Packing: in 25kgs fiber drums
Storage:Keep container unopened in cool, dry place,Keep away from strong light
Shelf Life:24 months from date of production
Genistein 98% HPLC, CAS 446-72-0 – High-Purity Isoflavone Powder for Research & Nutraceuticals
Product Overview
Genistein 98% is a synthetic or plant-derived isoflavone widely used in pharmaceutical research, nutraceuticals, and biochemical studies. With a purity ≥98% (HPLC-verified), this compound is available as a fine powder, ranging in color from off-white to pale yellow, depending on the source and processing method . Its CAS number (446-72-0) and molecular formula (C₁₅H₁₀O₅) ensure precise identification for regulatory compliance and research reproducibility .
Key Specifications
- Purity: ≥98% (HPLC)
- Appearance: Fine powder, off-white to yellow
- Melting Point: 297–298°C
- Solubility: Soluble in DMSO and ethanol; insoluble in water
- Storage: Stable at -20°C in airtight, light-protected containers
- CAS No.: 446-72-0
Applications
- Pharmaceutical Research
- Estrogen Receptor Studies: Acts as a ligand for estrogen receptors (ERα/ERβ), used in reporter gene assays and hormone-related cancer research .
- Anticancer Agent: Inhibits tyrosine kinases and topoisomerase II, reduces angiogenesis, and enhances the efficacy of chemotherapy drugs like doxorubicin .
- Anti-Inflammatory & Antioxidant: Mitigates oxidative stress by neutralizing free radicals, potentially aiding in chronic disease management (e.g., atherosclerosis, diabetes) .
- Nutraceuticals & Cosmetics
- Formulated into capsules, creams, and sustained-release suppositories for improved bioavailability. Used in women’s health products for its phytoestrogen properties and antioxidant support .
- Biochemical Tools
- Inhibits endocytosis in studies of lysosomal function and AGE-BSA interactions .
Biological Mechanisms
- Phytoestrogen Activity: Binds to estrogen receptors, modulating hormonal pathways without endogenous estrogen’s risks .
- Antioxidant Effects: Scavenges reactive oxygen species (ROS) and upregulates superoxide dismutase production .
- Synergistic Therapy: Enhances cytotoxicity of anticancer drugs in resistant breast cancer cells (e.g., MCF-7/Adr) .
Safety & Handling
- Hazards: May cause eye/skin irritation. Harmful if inhaled or ingested. Use PPE (gloves, lab coat, goggles) during handling .
- Carcinogenicity Note: Studies in neonatal mice indicate potential endocrine-dependent tumorigenicity at high doses .
- Storage: Store at -20°C; avoid exposure to moisture and light .
Why Choose Our Genistein 98%?
- High Purity: Rigorous HPLC testing ensures ≥98% purity for reliable results .
- Versatility: Suitable for diverse applications, from cell culture studies to nutraceutical development .
- Regulatory Compliance: Meets standards for research, cosmetics, and dietary supplements (non-clinical use) .
Contact Us
For technical data sheets, bulk inquiries, or custom formulations, visit [Your Company Website] or email [Contact Info]. Elevate your research with Genistein 98%—precision, potency, and proven performance.
Keywords: Genistein 98%, CAS 446-72-0, phytoestrogen, tyrosine kinase inhibitor, antioxidant, bulk supplier, HPLC purity.
Description: Premium Genistein 98% (CAS 446-72-0) for research and nutraceuticals. HPLC-verified purity, competitive pricing, and global shipping. Explore applications in cancer research, hormone studies, and antioxidant formulations.
