Product Name:Hydrogenated Phosphatidylcholine (PCH)
CAS No: 97281-48-6
Ingredient: ≧30% 50% 70% 90%
Color:white powder
GMO Status:GMO Free
Packing: in 25kgs fiber drums
Storage:Keep container unopened in cool, dry place,Keep away from strong light
Shelf Life:24 months from date of production
Hydrogenated Soy Phosphatidylcholine (HSPC) – High-Purity Excipient for Pharmaceutical & Cosmetic Applications
CAS No.: 97281-48-6 | 92128-87-5
Synonyms: HSPC, Hydrogenated Soya PC, Phospholipon® P90H
Product Overview
Hydrogenated Soy Phosphatidylcholine (HSPC) is a saturated phospholipid derived from soybean lecithin through catalytic hydrogenation. This process enhances its oxidative stability and reduces hygroscopicity, making it ideal for lipid-based drug delivery systems and cosmetic formulations .
Key Specifications
Property | Details |
---|---|
Molecular Formula | C44H88NO8P (from natural soybean) / C42H84NO8P (synthetic variants) |
Molecular Weight | 790.15 g/mol (natural) / 762.09 g/mol (synthetic) |
Purity | ≥70.0% (varies by grade; refer to COA for batch-specific data) |
Solubility | Soluble in chloroform, n-hexane, hot ethanol; insoluble in water |
Storage | Sealed, protected from light, frozen (-20°C); avoid strong oxidants |
Applications
- Drug Delivery Systems
- Primary component in liposomes and glycerosomes for sustained release of hydrophobic drugs (e.g., diclofenac) .
- Improves drug solubility and bioavailability via micelle encapsulation .
- Compatible with cholesterol and DSPE derivatives for functionalized carriers .
- Cosmetics & Medical Devices
- Stabilizes emulsions in topical formulations .
- Used in anti-aging creams and transdermal patches due to skin-barrier repair properties .
- Research & Diagnostics
- Standard material for lipid nanoparticle characterization (size, zeta potential) .
- Supports membrane studies in biochemistry .
Technical Advantages
- Enhanced Stability: Hydrogenation reduces unsaturated bonds, minimizing lipid peroxidation .
- Regulatory Compliance: Meets USP standards for pharmaceutical excipients (Grade: Cosmetics/Medical Devices/Pharmaceuticals) .
- Customizable Formats: Available as lyophilized powder, pre-formed liposomes, or solvent-dispersed solutions .
Manufacturers: AVT Pharmaceuticals (China) , Polysciences (USA) , Lipoid GmbH (Germany) .
Safety & Handling
- Precautions: Avoid strong acids/alkalis to prevent hydrolysis .
- Documentation: MSDS and COA provided upon request.
Keywords: Hydrogenated Phosphatidylcholine, HSPC Supplier, Liposome Excipient, Pharmaceutical-grade PC, CAS 97281-48-6