Hydrogenated Phosphatidylcholine

Short Description:

Phosphatidylcholine Powder (PC) is a phospholipid attached to a choline particle. Phospholipids contain fatty acids, glycerol, and phosphorous. The phosphorous part of the phospholipid substance — the lecithin — is made up of PC. For this reason, the terms phosphatidylcholine and lecithin are often used interchangeably, although they’re different. Foods that contain lecithin are the best dietary sources of PC. Phosphatidylcholine (PC) is a phospholipid attached to a choline particle. Phospholipids contain fatty acids, glycerol, and phosphorous.

Phosphatidylcholine(PC) also called neural acid compound.Is the cell membrane of the active material, especially exists in the brain cells. The main function is to improve the function of nerve cells, adjust the transmission of nerve impulses, enhance memory function, due to its strong lipotropy, absorbed quickly through the blood brain barrier into the brain, help relax vascular smooth muscle cells, increase the role of brain blood flow.


  • FOB Price: US 5 - 2000 / KG
  • Min.Order Quantity: 1 KG
  • Supply Ability: 10000 KG/per Month
  • Port: Shanghai /Beijing
  • Payment Terms: L/C,D/A,D/P,T/T,O/A
  • Shipping Terms: By sea/By Air/By Courier
  • Product Detail

    Product Tags

    Product Name:Hydrogenated Phosphatidylcholine (PCH)

    CAS No: 97281-48-6

    Ingredient: ≧30% 50% 70% 90%

    Color:white powder

    GMO Status:GMO Free

    Packing: in 25kgs fiber drums

    Storage:Keep container unopened in cool, dry place,Keep away from strong light

    Shelf Life:24 months from date of production

    Hydrogenated Soy Phosphatidylcholine (HSPC) – High-Purity Excipient for Pharmaceutical & Cosmetic Applications
    CAS No.: 97281-48-6 | 92128-87-5
    Synonyms: HSPC, Hydrogenated Soya PC, Phospholipon® P90H

    Product Overview

    Hydrogenated Soy Phosphatidylcholine (HSPC) is a saturated phospholipid derived from soybean lecithin through catalytic hydrogenation. This process enhances its oxidative stability and reduces hygroscopicity, making it ideal for lipid-based drug delivery systems and cosmetic formulations .

    Key Specifications

    Property Details
    Molecular Formula C44H88NO8P (from natural soybean)  / C42H84NO8P (synthetic variants) 
    Molecular Weight 790.15 g/mol (natural) / 762.09 g/mol (synthetic) 
    Purity ≥70.0% (varies by grade; refer to COA for batch-specific data) 
    Solubility Soluble in chloroform, n-hexane, hot ethanol; insoluble in water 
    Storage Sealed, protected from light, frozen (-20°C); avoid strong oxidants 

    Applications

    1. Drug Delivery Systems
      • Primary component in liposomes and glycerosomes for sustained release of hydrophobic drugs (e.g., diclofenac) .
      • Improves drug solubility and bioavailability via micelle encapsulation .
      • Compatible with cholesterol and DSPE derivatives for functionalized carriers .
    2. Cosmetics & Medical Devices
      • Stabilizes emulsions in topical formulations .
      • Used in anti-aging creams and transdermal patches due to skin-barrier repair properties .
    3. Research & Diagnostics
      • Standard material for lipid nanoparticle characterization (size, zeta potential) .
      • Supports membrane studies in biochemistry .

    Technical Advantages

    • Enhanced Stability: Hydrogenation reduces unsaturated bonds, minimizing lipid peroxidation .
    • Regulatory Compliance: Meets USP standards for pharmaceutical excipients (Grade: Cosmetics/Medical Devices/Pharmaceuticals) .
    • Customizable Formats: Available as lyophilized powder, pre-formed liposomes, or solvent-dispersed solutions .

    Manufacturers: AVT Pharmaceuticals (China) , Polysciences (USA) , Lipoid GmbH (Germany) .

    Safety & Handling

    • Precautions: Avoid strong acids/alkalis to prevent hydrolysis .
    • Documentation: MSDS and COA provided upon request.

    Keywords: Hydrogenated Phosphatidylcholine, HSPC Supplier, Liposome Excipient, Pharmaceutical-grade PC, CAS 97281-48-6


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