Indole-3-Carbinol 98%

Short Description:

Indole 3 carbinol (C9H9NO) is produced by the breakdown of the glucosinolate glucobrassicin, which can be found at relatively high levels in cruciferous vegetables such as broccoli, cabbage, cauliflower, brussels sprouts, collard greens and kale. indole-3-carbinol is also available in a dietary supplement. indole-3-carbinol is the subject of on-going Biomedical research into its possible anticarcinogenic, antioxidant, and antiatherogenic effects.

Indole-3-carbinol can shift estrogen metabolism towards less estrogenic metabolites. indole-3-carbinol has an effect on human papilloma virus infected cells in both pediatrics and adult patients.

Research on indole-3-carbinol has been conducted primarily using laboratory animals and cultured cells. Limited and inconclusive human studies have been reported. A recent review of the biomedical research literature found that “evidence of an inverse association between cruciferous vegetable intake and breast or prostate cancer in humans is limited and inconsistent” and “larger randomized controlled trials are needed” to determine if supplemental indole-3-carbinol has health benefits.

 

 


  • FOB Price: US 5 - 2000 / KG
  • Min.Order Quantity: 1 KG
  • Supply Ability: 10000 KG/per Month
  • Port: Shanghai /Beijing
  • Payment Terms: L/C,D/A,D/P,T/T,O/A
  • Shipping Terms: By sea/By Air/By Courier
  • E-mail:: info@trbextract.com
  • Product Detail

    Product Tags

    Product Name:Indole-3-Carbinol 98%

    Specification:98% by HPLC

    Botanic Source:broccoli extract

    CAS No:700-06-1

    Plant Part Used:dried seeds

    [Synonym]:4-methylsulfinybutyl isothiocyanatel;Sulforafan;Sulforaphan;Sulphoraphane;(R)-sulforaphane;L-sulforaphane

    [Plant Source]:Broccoli seeds

    [Chemical name]: 1-isothiocyanato-4-(methyl-sulfinyl) butane

    [Structural formula]: C6H11S2NO [CAS Reg]:142825-10-3

    [Molecular weight]: 177.29

    Colour:Yellow brown to white powder with characteristic odor and taste

    GMO Status:GMO Free

    Packing: in 25kgs fiber drums

    Storage:Keep container unopened in cool, dry place,Keep away from strong light

    Shelf Life:24 months from date of production

    Indole-3-Carbinol 98% | Natural Detox & Hormone Balance Superstar

    CAS No.: 700-06-1 | Purity: 98% HPLC | Cruciferous Vegetable Extract | Non-GMO

    Product Overview

    Indole-3-Carbinol 98% (I3C) is a high-purity bioactive compound derived from cruciferous vegetables such as broccoli, Brussels sprouts, and cabbage. Renowned for its hormone-modulating, detoxification, and chemopreventive properties, this 98% HPLC-verified ingredient is ideal for dietary supplements, functional foods, and clinical research. Supported by over 500 scientific studies, it addresses modern health priorities including estrogen balance, cellular detoxification, and cancer risk reduction.

    Key Benefits

    ✅ Hormone Balance & Estrogen Metabolism

    • Promotes healthy estrogen metabolism by upregulating 2-hydroxylation pathway, reducing harmful estrogen metabolites (e.g., 4-OH estrogens).
    • Supports hormonal health in PCOS, menopause, and prostate conditions.

    ✅ Cellular Detoxification & Chemoprevention

    • Activates Ah receptor (aryl hydrocarbon receptor) to enhance detox enzymes (e.g., CYP1A1).
    • Induces apoptosis in cancer cells and inhibits tumor angiogenesis (preclinical data).

    ✅ Anti-Inflammatory & Antioxidant Defense

    • Reduces NF-κB activity to combat chronic inflammation.
    • Scavenges free radicals (ROS) and protects DNA from oxidative damage.

    ✅ Liver Health & Metabolic Support

    • Enhances glutathione synthesis for liver detoxification.
    • Modulates lipid metabolism to combat obesity-related disorders.

    ✅ Research-Backed Applications

    • Studied for breast, prostate, and cervical cancer prevention, HPV management, and autoimmune support.

    Applications

    1. Dietary Supplements
      • Capsules, tablets, or powders for hormone balance, detox, and immune support.
      • Suggested dosage: 100–400 mg/day (consult healthcare provider).
    2. Functional Foods & Beverages
      • Added to detox juices, cruciferous vegetable blends, or metabolic health formulas.
    3. Cosmetic Formulations
      • Anti-aging serums targeting hormonal acne and skin detoxification.
    4. Pharmaceutical R&D
      • Investigational compound for oncology, endocrinology, and autoimmune therapies.

    Quality & Compliance

     Certifications & Testing

    • 98% Purity by HPLC (COA provided).
    • Non-GMO, gluten-free, and allergen-free.
    • Heavy metals, pesticides, and microbes meet USP/EP standards.

     Storage & Stability

    • Store in airtight containers at 2–8°C (refrigerated) for long-term stability.
    • Shelf life: 12 months refrigerated; 6 months at room temperature (15–25°C).

    Why Choose Our Indole-3-Carbinol 98%?

     Science-Driven Formulations

    • Backed by clinical trials on estrogen metabolism and cancer chemoprevention.

    Customizable Formats

    • Available as bulk powder (1kg–50kg), enteric-coated capsules, or premixes.
    • MOQ flexible for startups and large-scale manufacturers.

    Global Regulatory Compliance

    • Compliant with FDA GRAS, EU Novel Food, and Health Canada NHP regulations.
    • Fast shipping to the USA, Europe, and Asia with full documentation support.

    FAQ

    Q: Is I3C safe for long-term use?
    A: Yes, human studies show safety at doses up to 400 mg/day. Avoid exceeding without medical guidance.

    Q: Can I3C interact with medications?
    A: May interact with estrogen-based therapies (e.g., birth control). Consult a doctor before use.

    Q: Do you provide stability testing for formulations?
    A: Yes! Our lab offers stability data for supplements, beverages, and topical products.

    Order Now

    KeywordsIndole-3-Carbinol 98% Supplier, Natural Hormone Balance Supplement, Cruciferous Detox Extract, High Purity I3C Powder

     


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