Product Name: L-5-MTHF Calcium powder
CAS number: 151533-22-1
Specifications: 99%
Colour:white to light yellowpowder with characteristic odor and taste
GMO Status:GMO Free
Packing: in 25kgs fiber drums
Storage:Keep container unopened in cool, dry place,Keep away from strong light
Shelf Life:24 months from date of production
Product Name: L-5-Methyltetrahydrofolate Calcium Powder (CAS: 151533-22-1)
Synonyms: L-Methylfolate Calcium, 5-MTHF-Ca, Active Folate, Levomefolate Calcium
Product Overview
L-5-Methyltetrahydrofolate Calcium (5-MTHF-Ca) is the biologically active form of folate (Vitamin B9), directly usable by the body without requiring enzymatic conversion. Unlike synthetic folic acid, which must be metabolized via the MTHFR enzyme, 5-MTHF-Ca bypasses this step, making it ideal for individuals with MTHFR gene mutations . It is the only folate form that crosses the blood-brain barrier, supporting neurological health, DNA synthesis, and cardiovascular function .
Key Advantages
- Superior Bioavailability
- Directly absorbed and utilized, ensuring optimal folate levels even in individuals with impaired MTHFR enzyme activity .
- Crystalline form (not amorphous) for enhanced stability and shelf life (≥2 years at room temperature) .
- Clinically Proven Benefits
- Supports Mental Health: Effective in alleviating depression and diabetic neuropathy .
- Prenatal Protection: Reduces risks of neural tube defects (NTDs) and supports fetal development .
- Cardiovascular Health: Lowers homocysteine levels, a key risk factor for heart disease .
- Neurological Protection: May reduce risks of Alzheimer’s and Parkinson’s diseases .
- Regulatory Compliance
- USP 37 Standard: Meets stringent purity criteria (90.0–110.0% label claim) with ≤1.0% D-5-methylfolate impurity .
- Global Approvals: GRAS (USA), EFSA (EU), and JECFA certifications ensure safety for dietary supplements and fortified foods .
Applications
- Dietary Supplements: Ideal for prenatal vitamins, mood support, and cardiovascular health formulas.
- Pharmaceuticals: Used in antidepressants, anemia treatments, and homocysteine-lowering therapies .
- Functional Foods: Stable in powdered formulations for infant formula, meal replacements, and sports nutrition .
Quality Specifications
| Parameter | Standard |
|---|---|
| Purity (HPLC) | ≥95.0% (Crystalline Form) |
| D-5-Methylfolate Impurity | ≤1.0% |
| Heavy Metals (Pb, Cd, As) | ≤1.0 ppm |
| Solubility | Water-soluble |
| Storage | 2–8°C, protected from light |
Recommended Dosage
- Adults: 1–15 mg daily, depending on therapeutic needs (consult healthcare provider).
- Pregnant Women: 400–800 mcg/day to support fetal development .
Why Choose Our Product?
- GMP Manufacturing: Produced in cGMP-certified facilities with ISO compliance .
- Non-GMO & Vegan: Free from animal-derived ingredients, gluten, and allergens .
- Patented Stability: C-Crystal technology ensures superior dissolution and bioavailability compared to glucosamine salts .
Packaging & Storage
- Available Formats: Powder (1 kg to 25 kg bulk), capsules, or custom blends.
- Shelf Life: 24 months in sealed, moisture-proof containers.
Keywords
Bioactive Folate, Methylfolate Benefits, MTHFR Mutation Support, USP-Verified Folate, Prenatal Vitamin B9, Cardiovascular Health Supplement
