L-Pipecolic Acid Powder

Short Description:

Pipecolic acid (CAS No. 3105-95-1), also known as L-Pipecolic acid powder, piperidine-2-carboxylic acid, homoproline, or 2-piperidinecarboxylic acid, is a cyclic amino acid with the molecular formula C₆H₁₁NO₂ and a molecular weight of 129.16 g/mol. It naturally occurs in the human body as a metabolite of lysine. It can be found in various food sources, including legumes, particularly soybeans, and certain vegetables and fruits. Commercially available pipecolic acid typically appears as a white to off-white crystalline powder with a characteristic odor.

FOB Price: US 5 - 2000 / KG

Min.Order Quantity: 1 KG

Supply Ability: 10000 KG/per Month

Port: Shanghai /Beijing

Payment Terms: L/C,D/A,D/P,T/T,O/A

Shipping Terms: By sea/By Air/By Courier

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L-Pipecolic Acid Powder (99% Purity) – Product Description

Product Name: L-Pipecolic Acid Powder
CAS No.: 3105-95-1
Synonyms: L-Homoproline, (S)-(−)-2-Piperidinecarboxylic Acid
Molecular Formula: C₆H₁₁NO₂
Molecular Weight: 129.16 g/mol

The main use of L-pipecolic acid is as a multifunctional scaffold, and the biological activity of these drugs depends on the stereochemical structure of the piperidine portion. New-generation local anesthetic ropivacaine, anesthetic levobupivacaine, anticoagulant agatroban, immunosuppressant sirolimus, and immunosuppressant tacrolimus are all produced using L-pipecolic acid or its derivatives as the primary raw material.

Key Features

High Purity: ≥99% (titration method), suitable for precise analytical applications like GC/MS .
Appearance: White to light yellow crystalline powder .
Melting Point: 272°C (lit.) .
Solubility: Soluble in water and slightly soluble in DMSO .
Storage: Stable at -20°C for long-term storage; aqueous solutions recommended for immediate use .

Applications

Biochemical Research:
- Metabolite of L-lysine, involved in lysine metabolism pathways and peroxisomal disorders (e.g., Zellweger syndrome) .
- Potential neuroprotective agent with studies in neurology and psychiatry .
Pharmaceutical Development:
- Key intermediate for synthesizing chiral compounds and bioactive molecules .
Analytical Chemistry:
- Ideal for GC/MS analysis due to high purity and stability .

Safety & Handling

Hazard Statements:
- H315: Causes skin irritation.
- H319: Causes serious eye irritation.
- H335: May cause respiratory irritation .
Precautionary Measures:
- Wear protective gloves/eye protection (P280).
- Avoid inhalation of dust (P261).
- In case of eye contact, rinse immediately with water (P305+P351+P338) .
First Aid:
- Skin/eye contact: Rinse thoroughly with water.
- Inhalation: Move to fresh air and seek medical attention if needed .

Quality Assurance

Purity Verification: Non-aqueous titration and HPLC (CAD) analysis .
Compliance: Meets standards for laboratory use; not intended for medical or diagnostic purposes .