Larch Extract (80%-90% Dihydroquercetin by HPLC): Comprehensive Product Description
1. Product Overview
Botanical Name: Larix gmelinii (Dahurian Larch)
Extracted Part: Bark
Active Ingredient: Dihydroquercetin (DHQ, Taxifolin)
Purity: 80%-90% (Quantified by HPLC)
Dihydroquercetin, a potent flavonoid, is extracted from the bark of Larix gmelinii, a coniferous tree native to Siberia and Northeast Asia. Renowned for its exceptional antioxidant capacity, this compound is increasingly sought after in global markets for its applications in nutraceuticals, food additives, and cosmetics .
2. Extraction Process & Quality Control
Advanced Extraction Technology
- Solvent Selection: Ethanol or hydroalcoholic solutions are used as eco-friendly extraction agents, ensuring high yield and minimal environmental impact .
- Patented Purification: Multi-stage chromatographic purification (e.g., HPLC) enhances purity to 80%-90%, removing impurities while preserving bioactive integrity .
- Ultrasound-Assisted Extraction: This method optimizes efficiency, reducing extraction time and energy consumption while maintaining DHQ’s stability .
HPLC Validation
- Methodology: Reverse-phase HPLC with a C18 column (e.g., ZORBAX C18) and UV detection at 360 nm ensures precise quantification .
- Mobile Phase: Gradient elution with acetonitrile and acetic acid/water achieves optimal separation .
- Certification: Compliant with ISO and USP standards, with batch-specific Certificates of Analysis (CoA) .
3. Key Benefits & Mechanisms
Antioxidant Powerhouse
- ORAC Score: DHQ exhibits one of the highest Oxygen Radical Absorbance Capacity (ORAC) values among natural antioxidants, neutralizing free radicals and reducing oxidative stress .
- Cellular Protection: Protects cell membranes and mitochondrial DNA from lipid peroxidation, slowing aging processes .
Anti-Inflammatory & Cardioprotective Effects
- Vascular Health: Enhances endothelial function, reduces arterial stiffness, and lowers LDL cholesterol, supporting cardiovascular health .
- Metabolic Syndrome: Combined with arabinogalactan, DHQ mitigates risks associated with hypercholesterolemia and insulin resistance .
Neuroprotective & Immune-Boosting Properties
- Cognitive Support: Crosses the blood-brain barrier to protect neurons from oxidative damage, potentially delaying neurodegenerative diseases .
- Immune Modulation: Enhances natural killer (NK) cell activity and cytokine production, fortifying immune responses .
4. Applications
1. Nutraceuticals & Dietary Supplements
- Formulations: Capsules, tablets, or powders targeting antioxidant support, anti-aging, and metabolic health .
- Dosage: 50–200 mg/day, validated in clinical trials for safety and efficacy .
2. Functional Foods & Beverages
- Fortification: Added to dairy products, juices, and energy bars for enhanced shelf life and health benefits .
- Regulatory Compliance: Approved by the European Commission (EC) as a novel food ingredient (Regulation EC No 258/97) .
3. Cosmetics & Skincare
- Anti-Aging Creams: Reduces UV-induced skin damage and wrinkles via collagen synthesis .
- Emulsions: Phospholipid-based formulations improve DHQ’s dermal absorption .
4. Veterinary & Pet Care
- Feed Additives: Supports joint health, immune function, and oxidative stress reduction in pets .
5. Safety & Certifications
- Toxicology Studies: No observed adverse effects (NOAEL) at 1,500 mg/kg/day in animal models, confirming safety for human consumption .
- GRAS Status: Generally Recognized as Safe (GRAS) in the U.S. and EU .
- Sustainability: Sourced from ethically managed forests in Siberia and the Amur Region .
6. Packaging & Storage
- Form: White crystalline powder, hygroscopic; store in airtight containers at 4–8°C .
- Shelf Life: 24 months when protected from light and moisture .
7. Why Choose Our Product?
- Purity & Transparency: Rigorous HPLC testing ensures consistent 80%-90% DHQ content.
- Global Compliance: Meets FDA, EFSA, and ISO guidelines for export to the U.S., EU, and Asia.
- Custom Solutions: Available in bulk quantities (500 kg/month) with tailored formulations .
Keywords: Dihydroquercetin, Larch Extract, Taxifolin, Natural Antioxidant, HPLC-Validated, Cardiovascular Health, Anti-Aging, Larix gmelinii
