Product Name:Lemairamin (WGX-50)
Other Name:2-Propenamide, N-[2-(3,4-dimethoxyphenyl)ethyl]-3-phenyl-, (2E)-;Lemairamin (WGX-50)
CAS No:29946-61-0
Assay: 98.0%Min
Colour: White to off-white powder
Packing:25kg/DRUMS
Lemairamin (WGX-50): A Natural Compound for Neuroprotection, Anti-Aging, and Inflammation Regulation
CAS No.: 29946-61-0 | Molecular Formula: C₁₉H₂₁NO₃ | Purity: 98%
Product Overview
Lemairamin (WGX-50) is a high-purity natural compound extracted from Sichuan pepper (Zanthoxylum spp.), with a molecular weight of 311.36. It appears as a white to off-white powder and is widely used in dietary supplements, skincare, and pharmaceutical research due to its multi-functional properties .
Key Features
- High Purity & Safety:
- 98% purity achieved through advanced extraction and synthesis processes, ensuring high bioavailability and minimal side effects .
- Long-term safety validated in preclinical studies .
- Dual Applications:
- Neuroprotection: Acts as an α7 nicotinic acetylcholine receptor agonist, reducing neuroinflammation and Aβ oligomer accumulation, showing potential in Alzheimer’s disease treatment .
- Anti-Aging & Skincare: Enhances collagen synthesis, repairs hair follicles, reduces wrinkles, and improves skin elasticity. Also exhibits UV protection and antioxidant effects .
- Anti-Inflammatory & Antioxidant:
- Modulates pro-inflammatory cytokines (e.g., IL-6, TNF-α) and activates the Akt pathway, alleviating inflammation in neurological and gastrointestinal systems .
- Stability & Absorption:
- Stable under various storage conditions and rapidly absorbed by the human body .
Scientific Validation
- Cognitive Improvement: Morris water maze tests demonstrated WGX-50’s ability to reverse scopolamine-induced memory impairment in mice, enhancing spatial memory and navigation efficiency .
- Alzheimer’s Research: In transgenic mouse models, WGX-50 reduced Aβ-induced neuronal apoptosis and calcium toxicity, improving cognitive performance .
- Skin Efficacy: Increased collagen and elastin synthesis in aged mice, with visible reduction in age spots .
Applications
- Dietary Supplements: Supports brain health and anti-aging .
- Cosmetics: Used in anti-wrinkle creams, sunscreens, and anti-aging serums .
- Pharmaceutical Development: A candidate for Alzheimer’s disease and anti-inflammatory drugs .
Packaging & Storage
- Packaging: 1kg/bag, 25kg/drum (customizable for bulk orders) .
- Storage: Store in a cool, dry place away from direct sunlight .
Why Choose Lemairamin (WGX-50)?
- Natural & Sustainable: Sourced from renewable Sichuan pepper plants .
- Clinically Backed: Supported by peer-reviewed studies in journals like International Journal of Molecular Sciences .
- Versatile: Adaptable to supplements, cosmetics, and drug formulations .
Keywords
- Primary Keywords: Lemairamin, WGX-50, Natural Anti-Aging, Neuroprotective Compound, Alzheimer’s Research.
- Secondary Keywords: Sichuan Pepper Extract, Skin Elasticity, Dietary Supplement Raw Material, Anti-Inflammatory Agent.
Function:
1. Analgesic effect: Xanthoxylin has analgesic properties and can relieve pain symptoms. It can stimulate the body’s heat receptors, change the way pain is transmitted, and release endogenous pain-relieving substances, thereby reducing discomfort such as headaches and arthritis.
2. Antibacterial effect: Xanthophyllin has a certain antibacterial effect, which can inhibit the growth of bacteria and fungi. It is widely used in the food industry and health care products to keep food fresh and extend its shelf life.
3. Promote digestion: Xanthoxylum can stimulate the secretion of digestive glands, increase the secretion of gastric juice and saliva, thereby promoting the digestion process of food. It can also relieve GI problems like GI cramps and acid reflux.
4. Antioxidant effect: Xanthophyllin is a powerful antioxidant that can neutralize free radicals and reduce damage to cells caused by oxidative stress. This helps slow cellular aging, protects cardiovascular and neurological health, and prevents the development of chronic diseases.
