Limonin is a limonoid, and a bitter, white, crystalline substance found in citrus and other plants. It is also known as limonoate D-ring-lactone and limonoic acid di-delta-lactone. Chemically, it is a member of the class of compounds known as furanolactones.
Limonin is enriched in citrus fruits and is often found at higher concentrations in seeds, for example orange and lemon seeds. Limonin is also present in plants such as those of the Dictamnus genus.
Limonin and other limonoid compounds contribute to the bitter taste of some citrus food products. Researchers have proposed removal of limonoids from orange juice and other products (known as “debittering”) through the use of polymeric films.
Title: Premium Limonin (CAS 1180-71-8) | Natural Citrus Extract for Research & Pharmaceutical Use
Meta Description: High-purity Limonin (C26H30O8), a bioactive triterpenoid from citrus fruits, with anti-tumor, antiviral properties. CAS 1180-71-8, 98% purity. Available in 10mg/20mg.
Product Overview
Limonin (CAS 1180-71-8), also known as Evodine or Limonoate D-ring-lactone, is a naturally occurring triterpenoid compound extracted from citrus fruits such as oranges, grapefruits, and lemons . With the molecular formula C26H30O8 and a molecular weight of 470.51–470.52 g/mol, it appears as a white crystalline powder with a bitter taste .
Key Features
- High Purity: ≥98% purity (HPLC verified), ideal for laboratory research and pharmaceutical development .
- Bioactive Properties: Exhibits anti-tumor, antiviral, anti-inflammatory, and cholesterol-lowering effects .
- Stability: Stable for ≥2 years when stored at -20°C in sealed containers .
- Solubility: Slightly soluble in methanol and ethyl acetate; insoluble in water and ethanol .
Applications
- Pharmaceutical Research:
- Targets HIV protease and shows potential in antiviral drug development .
- Studied for its anti-cancer activity and apoptosis-inducing effects .
- Nutraceuticals:
- Used in dietary supplements for its antioxidant and anti-inflammatory benefits .
- Food Industry:
- Investigated for bitterness modulation in citrus-based products .
Safety & Handling
- Storage: Store in a dry, ventilated area at 2-8°C; avoid exposure to light and strong oxidizers .
- Safety Precautions:Disposal: Classified as non-hazardous waste but must comply with local regulations .
- Wear protective equipment (gloves, goggles) to prevent skin/eye contact .
- In case of inhalation or ingestion, seek medical attention immediately .
Specifications
| Parameter | Details |
|---|---|
| CAS No. | 1180-71-8 |
| Molecular Formula | C26H30O8 |
| Molecular Weight | 470.51–470.52 g/mol |
| Purity | ≥98% |
| Packaging | 10mg, 20mg, 25mg, 250mg, 1g |
| Solubility | Methanol, ethyl acetate |
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- Certified Quality: Sourced from ISO-certified manufacturers with batch-specific COA .
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Keywords: Limonin CAS 1180-71-8, Citrus Extract, Anti-tumor Compound, Triterpenoid, Pharmaceutical Grade, High-Purity Limonin
