Product Name: N-Boc-O-Benzyl-D-serine Powder
CAS No.:
Molecular Formula: C₁₅H₂₁NO₅
Molecular Weight: 295.33 g/mol
Purity: ≥98% (HPLC)
Appearance: White crystalline powder
Storage Conditions: Store at -20°C in a dry, dark, and sealed container
Product Overview
N-Boc-O-Benzyl-D-serine is a protected derivative of D-serine, widely used in peptide synthesis and pharmaceutical research. Its tert-butoxycarbonyl (Boc) and benzyl (Bzl) groups provide dual protection for the amino and hydroxyl functionalities, ensuring stability during complex synthetic processes .
Key Features
- High Purity: Rigorous quality control ensures HPLC purity ≥98% for reliable experimental outcomes .
- D-Stereochemistry: The D-configuration offers unique advantages in chiral drug development and bioactive peptide design .
- Dual Protection: Boc and Bzl groups prevent undesired side reactions during peptide chain assembly .
Applications
- Peptide Synthesis
- Solid-Phase Synthesis: The benzyl group is cleaved simultaneously with resin cleavage using HF or TFMSA .
- Solution-Phase Synthesis: Hydrogenolysis selectively removes the benzyl group while retaining the Boc protection .
- Hydrophilicity Enhancement: Serine residues improve peptide solubility and receptor binding via hydrogen bonding .
- Pharmaceutical Intermediates
- Used in synthesizing chiral drugs, enzyme inhibitors, and targeted therapies .
Safety & Handling
- Precautions: Avoid skin/eye contact and inhalation. Use PPE (gloves, goggles) in a well-ventilated area .
- First Aid: Rinse with water if exposed. Seek medical attention if necessary .
- Disposal: Follow local regulations for chemical waste disposal .
Regulatory Compliance
- Listed in China’s Chemical Inventory and compliant with REACH, TSCA, and ISO standards .
- Not classified as hazardous under IMDG/IMO regulations .
Why Choose Us?
- Quality Assurance: Batch-specific COA provided.
- Global Shipping: Fast delivery to the EU, US, and Asia.
- Technical Support: Expert guidance on synthesis protocols and applications.
Keywords:
N-Boc-O-Benzyl-D-serine, CAS 47173-80-8, Peptide Synthesis Reagent, D-Serine Derivative, Boc-Protected Amino Acid, Pharmaceutical Intermediate