Product name: Oleoylethanolamide, N-Oleoylethanolamide, OEA
Other name: N-(2-Hydroxyethyl)-9-Z-octadecenamide, N-oleoyl ethanolamide, Oleoyl monoethanolamide, 9-Octadecenamide , N-(2-Hydroxyethyl)oleamide
CAS No: 111-58-0
Molecular Formular: C20H39NO2
Molecular Weight:325.5
Assay:90%,95%, 85% min
Appearance :cream-colored powder
Oleoylethanolamide (OEA) Powder: Benefits, Applications, and Manufacturing
Introduction to Oleoylethanolamide (OEA)
Oleoylethanolamide (OEA), a naturally occurring fatty acid amide (C20H39NO2, CAS: 111-58-0), is synthesized in the small intestine and tissues . Structurally similar to endocannabinoids, OEA regulates metabolic and neurological functions, making it a key ingredient in nutraceuticals and research applications .
Key Benefits & Mechanisms
- Appetite Suppression & Weight Management
OEA activates PPARα receptors, reducing food intake and promoting fat oxidation. Studies show systemic administration (10 mg/kg) significantly inhibits weight gain in animal models . - Anti-Inflammatory & Neuroprotective Effects
OEA attenuates neuroinflammation and amyloid-beta pathology, demonstrating potential in neurodegenerative disease research . - Metabolic Regulation
Enhances lipid metabolism and liver health, with patented formulations targeting liver steatosis . - Mood & Anxiety Modulation
OEA interacts with central nervous pathways, offering therapeutic potential for anxiety disorders .
Applications
- Dietary Supplements: Formulated for weight management and metabolic health, available in powders (15%-50% purity) for easy dosing .
- Research Use: Investigated for obesity, atherosclerosis, and neuroprotection .
- Cosmeceuticals: Incorporated into anti-aging and anti-inflammatory skincare products .
Manufacturing Process
- Natural Extraction: Derived from olive oil via solvent extraction (ethanol/hexane), ensuring high bioavailability .
- Purification: Chromatography and distillation remove impurities, achieving ≥98% purity .
- Drying & Packaging: Lyophilized into stable powder, sealed in moisture-proof containers (25 kg/drum) .
Quality Assurance:
- GMP/ISO-Certified Facilities: Guarantee traceability and compliance with international standards .
- Third-Party Testing: Validates purity, heavy metals (<20 ppm), and residual solvents .
Safety & Storage
- Storage: -20°C for long-term stability (3 years); avoid light and moisture .
- Handling: Wear gloves and eye protection. May cause mild skin/eye irritation (GHS H315/H319) .
- Non-Hazardous Shipping: Transported with ice packs; complies with IATA/IMDG regulations .
Why Choose Our OEA Powder?
- High Purity: 99% verified by HPLC .
- Flexible Formulations: Custom concentrations (15%-50%) for capsules, tablets, or functional beverages .
- Global Logistics: Fast delivery from US/EU/China hubs .
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Keywords
Oleoylethanolamide Powder, OEA Weight Loss, PPARα Agonist, Natural Appetite Suppressant, GMP-Certified OEA, Neuroprotective Supplements, Bulk OEA Supplier