Product Name:Organic Germanium Sesquioxide
Other Name:carboxylethyl germanium sesquioxide,GE-132 Powder
CAS No:12758-40-6
Mesh:100mesh,200mesh
Symbol:GE-132
Assay:99.99%
Colour:White crystal powder with characteristic odor and taste
GMO Status:GMO Free
Packing: in 25kgs fiber drums
Storage:Keep container unopened in cool, dry place,Keep away from strong light
Shelf Life:24 months from date of production
Germanium Sesquioxide (CAS 12758-40-6)
Product Overview
Germanium Sesquioxide (CAS 12758-40-6), also known as Propagermanium or Ge-132, is an organogermanium compound with the chemical formula C₆H₁₀Ge₂O₇ and molecular weight 339.42 g/mol. It appears as a white, odorless, microcrystalline powder and is widely recognized for its low toxicity and unique biological activities .
Key synonyms include:
- 2-Carboxyethylgermanium sesquioxide
- Bis-(2-carboxyethylgermanium sesquioxide)
- β-Carboxyethylgermanium oxide
Safety Profile
Extensive studies confirm the safety of organic Germanium Sesquioxide:
- Animal Studies:
- Oral LD₅₀ exceeds 10,000 mg/kg in rats and 6,300 mg/kg in mice .
- Long-term exposure (6 months) at 3,000 mg/kg/day in rats showed no adverse effects .
- Human Studies:
- Doses up to 75 mg/kg in healthy volunteers caused no abnormalities in blood, urine, or organ function .
- Rapid renal excretion (80% within 72 hours) with no tissue accumulation .
- Comparative Safety:
- Lower toxicity compared to inorganic germanium compounds (e.g., germanium dioxide), which are linked to renal and neurological damage .
- No mutagenic, clastogenic, or carcinogenic effects observed in OECD-compliant tests .
Note: Ensure product purity to avoid contamination with inorganic germanium, which poses health risks .
Applications
Germanium Sesquioxide is utilized in:
- Health Supplements:
- Enhances immune function by stimulating natural killer (NK) cells, T-lymphocytes, and interferon-γ production .
- Promotes cellular oxygenation, supporting conditions like chronic fatigue and degenerative diseases .
- Medical Research:
- Investigated for anti-tumor and anti-viral properties, particularly in cancer and HIV/AIDS therapies .
- Industrial Uses:
- Intermediate in organic synthesis and specialty chemicals .
Regulatory Status: Marketed as a dietary supplement in the U.S. and Europe; not approved as a pharmaceutical drug .
Market Availability
- Global Producers: Major manufacturers in Europe, Asia, and North America .
- Regional Pricing:Certifications: Complies with REACH, TSCA, and GHS standards for safe handling and transport .
- North America: Competitive pricing with bulk discounts for industrial buyers .
- Europe: Stable supply chains through distributors like S3 Handel und Dienstleistungen UG .
Quality Assurance
- Purity Testing:Storage: Store in dry, ventilated areas away from moisture and oxidizers .
- Elemental Analysis: Confirms ≤42.7% germanium content (higher levels indicate inorganic contamination) .
- X-ray Fluorescence (XRF): Ensures quantifiable germanium purity .
Why Choose Our Product?
- High-Purity Organic Form: Guaranteed free from inorganic contaminants.
- Global Compliance: Meets FDA, EU, and ISO guidelines for safety and traceability.
- Technical Support: Access to SDS, analytical reports, and customized solutions.
- Keywords::Germanium Sesquioxide, Ge-132, CAS 12758-40-6, Organic Germanium, Immune Booster, Low Toxicity, Supplier Pricing
