Product Name: Psoralea Corylifolia Extract 90%-99% Bakuchiol (HPLC Verified)
Latin Name: Psoralea corylifolia L.
Extraction Part: Seeds
CAS Number: 10309-37-2
Molecular Formula: C₁₈H₂₄O
Molecular Weight: 256.38 g/mol
1. Product Overview
Psoralea Corylifolia Extract, standardized to 90%-99% Bakuchiol via High-Performance Liquid Chromatography (HPLC), is a revolutionary botanical ingredient derived from the seeds of the Psoralea corylifolia plant (commonly known as Babchi). Native to India and widely used in Ayurvedic and Traditional Chinese Medicine, this extract has gained global recognition as a natural alternative to retinol due to its potent anti-aging, antioxidant, and skin-rejuvenating properties .
Key Highlights:
- Purity: ≥99% Bakuchiol confirmed by HPLC, ensuring consistent efficacy and safety .
- Sustainability: Ethically sourced and processed using supercritical CO₂ extraction to preserve bioactive compounds .
- Versatility: Suitable for cosmetics, nutraceuticals, and functional foods.
2. Extraction and Quality Control
Extraction Process
The seeds of Psoralea corylifolia undergo a multi-step extraction protocol:
- Solvent Extraction: Hexane or ethanol is used to isolate crude Bakuchiol .
- Chromatographic Purification: HPLC and column chromatography refine the extract to ≥99% purity .
- Quality Testing: Rigorous checks for heavy metals (Pb, As, Hg ≤1 ppm), microbial limits (total bacteria ≤100 CFU/g), and residual solvents (methanol ≤25 ppm) ensure compliance with international standards (ISO 22000, HALAL, Kosher) .
Analytical Methods
- HPLC-DAD/ELSD: Quantifies Bakuchiol content and detects impurities like psoralen/isopsoralen (≤25 ppm) .
- GC-MS/NMR: Validates molecular structure and purity .
3. Key Benefits and Mechanisms of Action
Anti-Aging and Collagen Synthesis
- Collagen Activation: Stimulates Type I, III, and IV collagen production, improving skin elasticity and reducing wrinkles .
- Hyaluronic Acid Boost: Upregulates HAS3 enzyme, enhancing skin hydration .
- Antioxidant Protection: Neutralizes free radicals (ROS) and inhibits lipid peroxidation, preventing UV-induced damage .
- Non-Irritating: Unlike retinol, Bakuchiol does not cause dryness, redness, or photosensitivity, making it ideal for sensitive and acne-prone skin .
- Anti-Inflammatory: Reduces acne lesions by suppressing P. aeruginosa biofilms and regulating sebum production .
- Anti-Microbial: Inhibits pathogens like C. violaceum and S. marcescens via quorum-sensing disruption .
- Bone Health: Promotes osteoblast activity and reduces postmenopausal bone loss .
- Food Preservation: Acts as a natural antioxidant in baked goods and ice creams .
Gentle on Sensitive Skin
Additional Applications
4. Application Fields
Cosmetics
- Serums/Creams: Use at 0.5%-2% in anti-aging formulations. Combines well with niacinamide, squalane, and galactomyces .
- Sunscreens: Enhances UV resistance without sensitizing the skin .
- Acne Treatments: Paired with salicylic acid for synergistic effects .
- Joint Supplements: Supports cartilage regeneration via PI3K-Akt/ERK pathways .
- Anti-Diabetic Formulations: Mitigates nephropathy through antioxidant mechanisms .
- Natural Preservative: Extends shelf life in color-sensitive products like cakes .
Nutraceuticals
Food Industry
5. Usage Guidelines
- Skincare: Mix with dimethyl isosorbide (2%-3%) to enhance penetration. Avoid heating above 75°C to preserve stability .
- Storage: Keep in airtight containers at 4°C, protected from light .
6. Safety and Certifications
- Non-Toxic: LD₅₀ >2,000 mg/kg (oral, rats) .
- Certifications: ISO 22000, HALAL, Kosher, and vegan/cruelty-free compliance .
- Regulatory Status: Listed in CTFA and China’s Cosmetic Ingredient Directory .
7. Market Advantages
- SEO Keywords: ”Natural Retinol Alternative,” “Bakuchiol 99% HPLC,” “Vegan Anti-Aging Serum.”
- Competitive Edge: Combines traditional herbal wisdom with cutting-edge HPLC verification, appealing to eco-conscious consumers .
8. References
- Clinical efficacy of Bakuchiol in reducing wrinkles (British Journal of Dermatology) .
- Anti-biofilm activity against P. aeruginosa (Molecules, 2018) .
- Collagen synthesis pathways (Journal of Cosmetic Science)
