Shikimic acid 98.0%

Short Description:

Shikimic acid is a white crystalline compound of nonnitrogenous acid found in various plants naturally. It has two kind functional groups in the same molecule, three hydroxyl groups and a carboxylic acid group, which are optically active. They can yield various kinds of esters and salts. Shikimic acid is a cyclitol, a polyhydroxylated cycloalkane containing at least three hydroxy groups in the ring at different positions. Examples are inositol and quinic acid.The most important feature of cyclitol is that there are chiral isomers, key intermediates in the biosynthesis of aromatic compounds in living metabolism. Shikimic acid is a key intermediate in the biochemical pathway from phosphoenolpyruvic acid to tyrosine.


  • FOB Price: US 5 - 2000 / KG
  • Min.Order Quantity: 1 KG
  • Supply Ability: 10000 KG/per Month
  • Port: Shanghai /Beijing
  • Payment Terms: L/C,D/A,D/P,T/T,O/A
  • Shipping Terms: By sea/By Air/By Courier
  • Product Detail

    Product Tags

    Product Name:Shikimic acid 98.0%

    Botanical Source:Star Anise Extract

    Latin Name:Illicium verum Hook .f

    Part: Seed(Dried, 100% Natural)
    Extraction Method: Water/ Grain Alcohol
    Form: white powder
    Specification: 95%-99%

    Test Method : HPLC

    CAS NO.: 138-59-0

    Molecular Formula: C7H10O5

    Molecular Weight:174.15

    GMO Status:GMO Free

    Packing: in 25kgs fiber drums

    Storage:Keep container unopened in cool, dry place,Keep away from strong light

    Shelf Life:24 months from date of production

    Shikimic Acid 98.0%: High-Purity Intermediate for Pharmaceutical and Industrial Applications

    Product Overview

    Shikimic Acid (CAS 138-59-0) is a naturally occurring chiral compound, widely recognized as a critical intermediate in the biosynthesis of aromatic amino acids and pharmaceutical agents. With a purity of ≥98.0% (HPLC verified), our product meets stringent quality standards for research, pharmaceutical synthesis, and industrial applications. Derived from advanced microbial fermentation technology, it offers a sustainable and cost-effective alternative to traditional plant extraction methods .

    Key Features

    • High Purity: ≥98.0% (HPLC validated), ensuring reliability for sensitive applications like drug formulation .
    • Versatile Solubility: Soluble in ethanol (2.5 mg/ml), DMSO (25 mg/ml), and PBS (10 mg/ml at pH 7.2). Aqueous solutions are stable for 24 hours .
    • Long-Term Stability: Stable for ≥4 years when stored at -20°C in crystalline form .
    • Sustainable Production: Produced via genetically engineered Bacillus subtilis strains, optimizing yield (up to 87 g/L) and reducing environmental impact .

    Applications

    1. Pharmaceuticals:
      • Antiviral Drug Synthesis: Key precursor for Oseltamivir (Tamiflu®), a frontline treatment for influenza A/B and swine/avian flu .
      • Anti-Inflammatory & Antioxidant: Reduces oxidative stress in colitis models (40–80 µM) and inhibits pro-inflammatory cytokines .
      • Osteoporosis Therapy: Suppresses RANK/TRAF6 interaction, mitigating bone loss in ovariectomized mice (50–200 mg/kg) .
    2. Cosmetics:
      • Skin Whitening: Inhibits tyrosinase activity, reducing melanin formation for hyperpigmentation treatment .
      • Anti-Aging Formulations: Enhances exfoliation and antioxidant protection in premium skincare products .
    3. Biomedical Research:
      • Metabolic pathway studies (e.g., aromatic amino acid biosynthesis) .
      • Ligand binding assays and cytotoxicity screening .

    Technical Specifications

    Parameter Details
    Molecular Formula C₇H₁₀O₅
    Molecular Weight 174.2 g/mol
    Purity ≥98.0% (HPLC)
    Appearance White to off-white crystalline solid
    Storage -20°C in airtight container
    Stability ≥4 years
    Safety For research use only. Not for human consumption.

    Market Advantage

    • High Demand: Global market growth driven by pharmaceutical needs (e.g., Tamiflu® production) and cosmetic innovations .
    • Price Stability: Fermentation-based production mitigates supply chain risks from plant-derived shortages .
    • Regulatory Compliance: Meets USP/EP standards for pharmaceutical-grade ingredients .

    Why Choose Us?

    • Quality Assurance: Batch-specific HPLC reports and ISO-certified manufacturing .
    • Scalable Supply: Capable of bulk production (up to 14L bioreactor scale) with rapid delivery .
    • Technical Support: Dedicated team for application guidance and custom synthesis inquiries.

    Keywords

    Shikimic Acid 98%, High Purity Shikimic Acid, Tamiflu Precursor, Anti-Inflammatory Compound, Skin Whitening Agent, Microbial Fermentation, Pharmaceutical Intermediate, Osteoporosis Research.


  • Previous:
  • Next: