10-Deacetylbaccatin III (10-DAB)

10-Deacetylbaccatin III (10-DAB) Ata Fa'aalia
  • 10-Deacetylbaccatin III (10-DAB)

Fa'amatalaga Puupuu:

10-Deacetylbaccatin III (C29H36O10) o se bioactive diterpenoid e maua mai i nila ma pa'u o le laau.lafogaituaiga (laau yew). I le avea ai o se faʻamuamua autu i le semi-synthesis o paclitaxel, docetaxel, ma isi vailaʻau chemotherapeutic faʻavae lafoga, 10-DAB e faʻaaogaina lautele i vailaʻau R&D ma le gaosiga o vailaʻau oncology.

10-Deacetylbaccatin III, e lauiloa foi o le 10-DAB poʻo le 10-DAB III, o se faʻalapotopotoga faʻale-natura vavalalata vavalalata faʻaesea mai nila mago ma lala laiti o le laʻau yew Europa (Taxus baccata). pacitaxel (taxol); cabazitaxel. 10-10-deacetylbaccatin III na maua e filifili faʻalavelave le tuputupu aʻe o L. DONOVANI intracellular amastigotes i totonu J774 murine macrophages in vitro i nanomolar concentrations ma se IC (50) tau o le 70 nM.


  • FOB Tau:US 5 - 2000 / KG
  • Min. Order Quantity:1 KG
  • Avanoa Avanoa:10000 KG/masina
  • Taulaga:Shanghai/Beijing
  • Tulaga totogi:L/C,D/A,D/P,T/T,O/A
  • Tulaga va'a:I le sami/Ea/Ea/E ala i le Courier
  • I-meli:: info@trbextract.com
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    Fa'amatalaga Oloa

    Faailoga o oloa

    Igoa vaila'au: 10-Deacetylbaccatin III

    Numera CAS:

    32981-86-5
    upu uiga tutusa:

    10-Desacetylbaccatin III; 10β-Deacetylbaccatin III; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dod ecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one; 7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-tasi, 12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-; (Docetaxel USP Le mama);10-Deacetylbaccatin III; 10-Deacetyl baccatin; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-1,2a,3,4,4a,6,9,10,11,12,12a, 12b-Dodecahydro-4,6,9,11,12,12b-hexahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca [3,4] benz [1,2-b] oxet-5-one 12b-acetate, 12-benzoate (USP);
    Tulaga mole: C29H36O10
    Fa'aaliga: Pa'epa'e Malosi
    Mol. mamafa: 544.6
    Teuina: 2-8°C pusaaisa

    Ulutala: API Intermediate, CAS32981-86-5| GMP Certified, COA Tuuina atu

    O le a le 10-Deacetylbaccatin III (10-DAB)?

    10-Deacetylbaccatin III (C29H36O10) o se bioactive diterpenoid e maua mai i nila ma pa'u o le laau.lafogaituaiga (laau yew). I le avea ai o se faʻamuamua autu i le semi-synthesis o paclitaxel, docetaxel, ma isi vailaʻau chemotherapeutic faʻavae lafoga, 10-DAB e faʻaaogaina lautele i vailaʻau R&D ma le gaosiga o vailaʻau oncology.

    Fa'amatalaga Autu & Fa'aaliga

    • Mama: ≥98% (HPLC-UV faʻamaonia, COA avanoa)
    • Fa'aaliga: Pa'epa'e i le pa'epa'e pa'epa'e tioata
    • Solubility: Solu i le methanol, ethanol, DMSO; solu teisi i le vai
    • Teuina: Faʻamau i le -20°C i totonu o pusa malulu, puipuia mai le malamalama
    • Punavai La'au: Fa'atosina le seleselegaTaxus wallichiana(Himalayan yew)

    Talosaga a le 10-DAB

    1. Fa'agata Fa'ama'i Fa'ama'i
      • Tulaga taua mo le gaosiga semi-synthetic o paclitaxel (Taxol®) ma docetaxel (Taxotere®).
      • Fa'aoga ile R&D mo tala fou o lafoga o lo'o fa'atatau ile kanesa e tete'e i vaila'au.
    2. Suesuega Biochemical
      • Suesuega o tubulin polymerization mechanisms ma apoptosis induction.
      • Fa'asinomaga tulaga mo su'esu'ega kemisi ma le lelei pulea.
    3. Aveesega o Mea Faanatura
      • Fa'atosina maualuga e maua mai e fa'atatau ile kemisi lanu meamata.

    Aisea e maua ai le Puna 10-DAB mai ia i matou?

    ✅ Tulaga Fa'amaonia:

    • Tusi Pasi Fa'apitoa o Su'esu'ega (COA) fa'atasi ma HPLC, MS, NMR fa'amaumauga.
    • Faʻatasi ma USP, EP, ma ICH Q7 GMP taʻiala.

    ✅ Sustainable Sourcing:

    • Fa'ato'a seleseleina mai fa'ato'aga Taxus fa'ato'aga (CITES Appendix II fa'amalieina).

    ✅ Fa'atauga Fa'alelalolagi:

    • E leai se fela'ua'iga fe'avea'i filifili malulu i Amerika, EU, ma APAC itulagi.
    • Fa'apipi'i fa'apitoa (1g i le 1kg, ipu tioata amber ma fa'amago).

    Lagolago Fa'atekinisi & Fa'amaumauga

    • Free MSDS (Material Safety Data Sheet) ma faʻamaumauga mautu pe a talosagaina.
    • Fa'asologa fa'apitoa ma tau tele e avanoa mo pa'aga OEM.
    • Lagolago fa'atonutonu fa'apitoa mo talosaga a le IND/NDA.

    Saogalemu & Tausi

    • Numera CAS: 32981-86-5
    • Fa'ailoga o Tulaga Lamatia: Uu ma PPE (totini lima, matatioata) - e le lamatia mo le fa'aoga fa'apolofesa.
    • Tulaga Fa'atonutonu: REACH resitala; DMF avanoa mo tagata fa'atau vaila'au.

    FAQs mo 10-DAB

    Q: E mafai ona fa'aoga sa'o le 10-DAB i su'esu'ega aganu'u sela?
    A: Leai. E mana'omia le suiga o vaila'au (fa'ata'ita'iga, fa'aopoopo i le filifili pito) ina ia avea ma lafoga fa'aolaola.

    Q: O le a le taimi taʻimua mo 500g poloaiga?
    A: Taimi gaosiga masani: 2-3 vaiaso. E avanoa le felauaiga fa'aalia.

    Q: E te tu'uina atu fa'asologa o fa'asologa o lafoga?
    A: Ioe! Pepa paepae fa'apitoa e avanoa mo tagata fa'atauva'a.

    Fa'amatalaga:
    Punavai 98% HPLC-vasega 10-Deacetylbaccatin III (CAS 32981-86-5) - GMP-faʻamaonia Taxus extract mo paclitaxel synthesis. Fa'atonuga tele, COA/MSDS, ma le lagolago fa'atonutonu e aofia ai.

    1. upu autu:
      • Primary: “10-Deacetylbaccatin III supplier”, “Mauga maualuga 10-DAB”, “Paclitaxel precursor”
      • Si'usi'u umi: “CAS 32981-86-5 tau”, “Taxus extract for cancer research”, “GMP 10-DAB”
    2. upu autu:
      • “Taxane intermediate”, “semi-synthetic paclitaxel”, “C29H36O10″, “yew tree compound”
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