Mushonga wechisikigo unowanikwa mumastrawberries nemimwe michero nemiriwo unogona kubatsira kudzivirira chirwere cheAlzheimer nezvimwe zvirwere zvine hukama neurodegenerative, tsvagiridzo itsva inoratidza.
Vatsvagiri kubva kuSalk Institute for Biological Studies muLa Jolla, CA, uye vavanoshanda navo vakawana kuti kurapa mbeva yemhando yekuchembera nefisetin kwakakonzera kudzikiswa kwekuderera kwekuziva uye kuzvimba kwehuropi.
Munyori mukuru wechidzidzo Pamela Maher, weCellular Neurobiology Laboratory kuSalk, uye vaaishanda navo nguva pfupi yadarika vakashuma zvavakawana muThe Journals of Gerontology Series A.
Fisetin is flavanol iripo mune zvakasiyana siyana zvemichero nemiriwo, kusanganisira sitirobheri, persimmons, maapuro, mazambiringa, hanyanisi, uye magaka.
Haisi chete kuti fisetin inoshanda semushonga wemavara wemichero nemiriwo, asi zvidzidzo zvakaratidzawo kuti komboni ine antioxidant zvimiro, zvichireva kuti inogona kubatsira kudzikamisa kukuvara kwesero kunokonzerwa nemahara radicals.Fisetin yakaratidzawo kuderedza kuzvimba.
Kwemakore gumi apfuura, Maher nevamwe vaaishanda navo vakaita zvidzidzo zvakawanda zvinoratidza kuti antioxidant uye anti-inflammatory properties yefisetin inogona kubatsira kuchengetedza masero europi kubva pamigumisiro yekukwegura.
Imwe ongororo yakadai, yakabudiswa muna 2014, yakawana kuti fisetin yakaderedza kurasikirwa kwekuyeuka mumakonzo echirwere cheAlzheimer.Zvisinei, chidzidzo ichocho chakanangana nemigumisiro yefisetin mumakonzo ane mhuri yeAlzheimer's, iyo vatsvakurudzi vanocherechedza inongotora kusvika ku3 muzana yezviitiko zvose zveAlzheimer.
Pachidzidzo chitsva ichi, Maher nechikwata vakatsvaga kuona kana fisetin ingave nemabhenefiti echirwere cheAlzheimer's sporadic, inova ndiyo yakajairika fomu inomuka nezera.
Kuti vasvike zvavakawana, vaongorori vakaedza fisetin mumakonzo akange akagadzirwa kuti achembera nguva isati yakwana, zvichikonzera muenzaniso wembeva wechirwere cheAlzheimer's sporadic.
Apo mbeva dzaisakura nguva isati yakwana dzaive nemwedzi mitatu, dzakakamurwa kuita mapoka maviri.Rimwe boka rakadyiswa chipimo chefisetin nezvokudya zvaro zuva nezuva kwemwedzi 7, kutozosvikira vasvika zera remwedzi gumi.Rimwe boka harina kugamuchira komboni.
Chikwata chinotsanangura kuti pazera remwedzi gumi, mamiriro emuviri uye ekuziva emakonzo aive akaenzana neaya e2-year-old mbeva.
Makonzo ese aive pasi pekuziva uye maitiro ekuyedzwa mukati mekudzidza, uye vaongorori vakaongororawo mbeva dzemazinga emakaki ane chekuita nekushushikana uye kuzvimba.
Vatsvakurudzi vakawana kuti mbeva dzemwedzi we10 dzisina kugamuchira fisetin dzakaratidza kuwedzera kwezviratidzo zvakabatanidzwa nekushungurudzika uye kuzvimba, uye ivo vakaitawo zvakanyanya kuipa mukuongororwa kwepfungwa kupfuura mbeva dzakabatwa nefisetin.
Muhuropi hwemakonzo asina kurapwa, vaongorori vakawana kuti marudzi maviri eeuroni anowanzo anti-kuzvimba - astrocytes uye microglia - ainyatso kusimudzira kuzvimba.Zvakadaro, izvi handizvo zvakaitika kune mbeva dzemwedzi gumi dzakabatwa nefisetin.
Zvakare, vaongorori vakawana kuti hunhu uye hunyanzvi hwekuita mbeva dzakarapwa dzaive dzakafanana nedze3-mwedzi-yekuzvarwa mbeva dzisina kurapwa.
Vatsvagiri vanotenda kuti zvavakawana zvinoratidza kuti fisetin inogona kutungamira kune nzira nyowani yekudzivirira yeAlzheimer's, pamwe nezvimwe zvirwere zvine hukama neurodegenerative.
"Zvichienderana nebasa redu riri kuenderera mberi, tinofunga kuti fisetin inogona kubatsira senzira yekudzivirira yezvirwere zvakawanda zvine chekuita nezera, kwete Alzheimer's chete, uye tinoda kukurudzira kuidzidza kwakasimba," anodaro Maher.
Zvisinei, vatsvakurudzi vanocherechedza kuti miedzo yekiriniki yevanhu inodiwa kuti isimbise migumisiro yavo.Vanotarisira kubatana nevamwe vaongorori kuti vazadzise chido ichi.
“Mbeva havasi vanhu, hongu.Asi pane zvakafanana zvakakwana zvatinofunga kuti fisetin inoda kunyatsotariswa, kwete chete nokuda kwezvingabvira kurapa AD [chirwere cheAlzheimer] asiwo kuderedza mimwe miuyo yokuziva ine chokuita nokukwegura, kazhinji.”
Nguva yekutumira: Kubvumbi-18-2020