Related tags: hutano hwemoyo, kusagadzikana kwemoyo kutadza, pqq basa sanitize_gpt_value2(gptValue) {var vOut=""; var aTags = gptValue.split(','); var reg = new RegExp('\\W+', "g " ); ye (var i=0; i"Seyakakosha organelle yekuchengetedza moyo kushanda, mitochondria inopa simba kurova kwemoyo wese.Kune humbowo hwakawanda hwekuti mitochondria ndiwo masimba emoyo.Zvisinei, semabhatiri ekare, mwoyo yevarwere vane chirwere chemoyo chisingaperi chinopedzisira chapera.“Maererano netsvakiridzo ichangobva kuburitswa.
Sezvo pyrroloquinoline quinone (PQQ) inoonekwa seinoshanda antioxidant cofactor mukuita kwekudzikisa uye oxidation, inoparadzirwa zvakanyanya mumhuka nechirimwa tishu.Izvo zvakakosha kune zvinoyamwisa izvo kushomeka kwePQQ kunokanganisa mitochondria uye mitochondrial basa remhando idzi.Zvekudya zvinovaka muviri.
Kunyangwe PQQ iine mamwe mavhitamini-senge zvivakwa, inoonekwa sekudya.Vanokurudzira enzyme vane imwe antioxidant effect, inowanzowanikwa mu kiwi, green pepper uye parsley.Vanhu vazhinji vanotora PQQ kuburikidza nekuwedzera.
Imwe yeakanyanya kukosha mhedzisiro yePQQ iri pamitochondria.Mitochondria inopa maseru edu simba (ATP) uye inogadzirisa sero metabolism.Vatsvagiri vakadzidza zvakanyanya mhedzisiro yePPQ pamitochondria uye vakawana kuti PQQ inogona kuwedzera huwandu uye kugona kwemitochondria.
Kuti uongorore marapirwo matsva ekutadza kusimba kwemoyo, mupi wezvekudya kunovaka muviri uye mugadziri Nascent Health Sayenzi nguva pfupi yadarika yakabatana neCardiology Dhipatimendi reNantong University Hospital muChina kuti vadzidze maitiro ePQQ pakuvandudza kushanda kwemoyo.
Kunyanya, chidzidzo ichi chakaongorora mashandiro ePQQ pane mitochondrial basa mune yemoyo yekumanikidza yakawandisa modhi, uye yakaongorora kana PQQ inogona kuvandudza kushanda kwemoyo uye kubatsira kudzivirira kusingaperi kutadza kwemoyo.
Kuti uone mhedzisiro yePQQ pakusagadzikana kwemoyo uye kushanda kwechibvumirano mumuviri, makonzo ane mavhiki matanhatu akavhiyiwa 12-vhiki sham kana transaortic coarctation (TAC) kuvhiyiwa, uye akapihwa 0.4, 2 kana 10 mg / kg zuva nezuva PQQ. .
Mushure memavhiki e12 eTAC, makonzo akaratidza zvakakosha ventricular uye muscle cell hypertrophy uye kuwedzera kwehuremu hwemoyo / uremu hwemuviri.
Munyori akaratidzawo kuti migumisiro yekudzidza "inoratidza kuti 2 uye 10 mg / kg PQQ ine maitiro akanaka ekurapa;zvisinei, zvichienzaniswa ne 2 mg/kg PQQ, 10 mg/kg PQQ hairatidzi kutarisisa-inotsamira mhedzisiro, nepo 2 mg/kg PQQ isingaratidzi kutarisisa-inotsamira maitiro.Naizvozvo, PQQ ndiyo yakanakisa yekurapa dosi pakati pemapoka matatu.Mukuedza kunotevera, boka rekurapa reTAC + PQQ rakapihwa 2 mg/kg PQQ.
Kubva pane zvakawanikwa izvi, munyori anonongedza kuti kusanganiswa kwezvinhu zvese kunogona kubatsira kudzivirira kuitika kwekusagadzikana kwemoyo.
"Kekutanga munhoroondo, iyo ine simba antioxidant PQQ yakaratidza zvakanakira myocardial mitochondrial dysfunction uye CHF," akadaro Thomas Schrier, Mutevedzeri weMutungamiriri Wekutengesa, Nascent Health Sayenzi."Vaongorori vepaNantong University vari kutsvaga kurapwa kwemoyo mitochondrial basa, uye ikozvino vawana humbowo hwekuti kugona kwePQQ kumutsa mitochondrial biogenesis kunogona kudzivirira kukuvara kwemoyo uye kusimudzira hutano hwemoyo."
"Pyrroloquinoline quinone inogona kudzivirira kusingaperi kutadza kwemoyo nekudzora mitochondrial basa"
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Nguva yekutumira: Sep-01-2021