Spermidine Powder

Short Description:

Spermidine, first isolated from semen or sperm, is a water-soluble polyamine ingredient that occurs naturally in all tissues of our human bodies and also found in many other organisms like animals, plants, and typical dietary foods. Spermidine is able to penetrate biological membranes and believed to be beneficial to cell renewal and anti-aging purposes.

Spermidine is a small molecule with a molecular weight of 145.25, and unique CAS Registry Number as 124-20-9. It’s stable at room temperature. The color of Spermidine-rich wheat germ extract is white to yellowish powder, while for synthetic spermidine powder, the color is white to off-white. Spermidine is also available in the chloride form as spermidine trihydrochloride or spermidine 3 HCL (CAS 334-50-9).

Both spermine and spermidine are polyamines involved in cellular metabolism. Popular polyamines include agmatine (AGM), putrescine (PUT), cadaverine (CAD), spermine (SPM), and spermidine (SPD). Spermine is a crystalline powder compound and is related to spermidine, but is not the same.

Spermidine is a precursor to other polyamines, like spermine and thermospermine. The chemical name of spermidine is N-(3-aminopropyl) butane-1,4-diamine while the CAS number of spermine is 71-44-3 (free base) and 306-67-2 (tetrahydrochloride).


  • FOB Price: US 5 - 2000 / KG
  • Min.Order Quantity: 1 KG
  • Supply Ability: 10000 KG/per Month
  • Port: Shanghai /Beijing
  • Payment Terms: L/C,D/A,D/P,T/T,O/A
  • Shipping Terms: By sea/By Air/By Courier
  • E-mail:: info@trbextract.com
  • Product Detail

    Product Tags

    Product Name:Spermidine Powder

    CAS No.:334-50-9

    Assay: 99%

    Botanical Source:Wheat Germ Extract

    Appearance:White Fine powder

    Melting Point:22~25℃

    Status:GMO Free

    Packing: in 25kgs fiber drums

    Storage:Keep container unopened in cool, dry place,Keep away from strong light

    Shelf Life:24 months from date of production。

    Spermidine Powder: Anti-Aging & Longevity Supplement for Cellular Renewal

    Product Overview

    Spermidine Powder (CAS 124-20-9) is a naturally occurring polyamine critical for cellular health and longevity. With a molecular formula of C₇H₁₉N₃ and a purity of ≥99% (HPLC), our premium-grade supplement is synthesized using advanced biotechnology to ensure high bioavailability and stability . This white, water-soluble powder supports autophagy—the body’s cellular “cleanup” process—to combat aging, enhance vitality, and promote overall wellness .

    Key Benefits

    1. Anti-Aging & Longevity:
      • Stimulates autophagy to remove damaged cells, delaying age-related decline .
      • Extends lifespan in preclinical studies (e.g., C. elegans, mice) by up to 15% .
    2. Cellular & Metabolic Health:
      • Boosts mitochondrial energy production (ATP) by 4% at 0.1 µM .
      • Reduces oxidative stress by lowering H₂O₂ and O₂⁻ levels, protecting cells from damage .
    3. Heart & Brain Support:
      • Lowers blood pressure and prevents cardiac hypertrophy in salt-sensitive models .
      • Enhances cognitive function by mitigating neuroinflammation and oxidative stress .
    4. Hair & Skin Renewal:
      • Promotes hair growth and strengthens follicles via spermidine-rich wheat germ extracts .
      • Improves collagen synthesis for youthful skin .
    5. Anti-Inflammatory Effects:
      • Inhibits apoptosis induced by oxidative stress (e.g., H₂O₂ in retinal cells) .
      • Alleviates colitis and autoimmune inflammation by modulating macrophage activity .

    Why Choose Our Spermidine Powder?

    • High Purity & Safety: ≥99% purity (HPLC-tested), free from allergens (e.g., gluten) and contaminants .
    • Bioavailability: Trihydrochloride form ensures optimal absorption and stability compared to food sources .
    • Certified Quality: Compliant with ISO 9001, HACCP, and EU Novel Food Regulation (2020/443) .
    • Sustainable Production: Biosynthesized using eco-friendly methods, avoiding harmful byproducts .

    Recommended Use

    • Daily Dosage: 1–6 mg (aligned with EU safety guidelines) .
    • Applications: Capsules, tablets, skincare serums, hair growth formulations .
    • Storage: Store at 2–8°C in airtight containers to prevent oxidation .

    Spermidine vs. Food Sources

    While spermidine exists in foods like wheat germ (1% purity), soybeans, and aged cheese, cooking reduces its potency . Our supplement delivers 100x higher concentration than dietary sources, ensuring consistent efficacy without caloric excess .

    Safety & Side Effects

    • GRAS-Certified: Recognized as safe by the U.S. FDA and European Commission .
    • No Severe Side Effects: Well-tolerated in clinical studies; discontinue use if irritation occurs .

    FAQ

    Q: Is synthetic spermidine safe?
    A: Yes. Our biosynthetic process mirrors natural spermidine, ensuring safety and efficacy .

    Q: How does it compare to NMN?
    A: Spermidine activates autophagy for cellular renewal, while NMN focuses on energy metabolism. Combined use may amplify anti-aging effects .

    (Keywords: spermidine powder, anti-aging supplement, autophagy activator, longevity, cellular health)


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