Melatonin Powder

Short Description:

Melatonin is an indoleamine neurohormone found across plants and animals, produced endogenously from serotonin (5-HT) and secreted in animals as a regulatory signal for synchronization of the circadian rhythm and the sleep-wake cycle. The melatonin receptor system, consisting of the MEL-1A-R, MEL-1B-R, and MT3 subtypes, demonstrates particular plasticity and modularity – antagonists such as Luzindole (sc-202700) and 2-Phenylmelatonin (sc-203466) show modification of systemic responses to the Melatonin signal without impeding activation of the receptors by Melatonin. Powerful antioxidant activity is associated with Melatonin, and it is known to provide protection to lipids, proteins, and DNA against oxidative damage. Several antioxidant enzymes are shown to be upregulated by Melatonin, including glutathione peroxidase, superoxide dismutases, and catalase. Melatonin also scavenges free radicals as a terminal antioxidant, reacting to generate stable end products and terminate radical chain reactions. Free movement through the blood-brain barrier positions Melatonin as a particularly significant endogenous antioxidant. Melatonin is a rat NOS1 (nNOS) inhibitor. Melatonin is an activator of MEL-1A-R and MEL-1B-R.

FOB Price: US 5 - 2000 / KG

Min.Order Quantity: 1 KG

Supply Ability: 10000 KG/per Month

Port: Shanghai /Beijing

Payment Terms: L/C,D/A,D/P,T/T,O/A

Shipping Terms: By sea/By Air/By Courier

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Product Detail

Product Tags

Product Name:Melatonin

CAS No: 73-31-4

Ingredient: Melatonin 99% by HPLC

Colour: off-white to light yellow powder with characteristic odor and taste

GMO Status:GMO Free

Packing: in 25kgs fiber drums

Storage:Keep container unopened in cool, dry place,Keep away from strong light

Shelf Life:24 months from date of production

Melatonin Powder – Premium Sleep Support Supplement

Product Overview
Melatonin Powder (CAS 73-31-4) is a high-purity (>99%), naturally derived hormone synthesized from tryptophan, widely recognized for its role in regulating circadian rhythms and improving sleep quality. As a white crystalline powder with excellent solubility in ethanol (≥50 mg/mL), it is ideal for formulating dietary supplements, pharmaceuticals, and topical applications .

Key Benefits

Sleep Regulation: Supports healthy sleep patterns by synchronizing the body’s internal clock, reducing time to fall asleep, and enhancing sleep duration .
Antioxidant & Anti-Aging: Neutralizes free radicals, protects DNA from oxidative stress, and promotes skin elasticity .
Immune & Mood Support: Modulates immune function, reduces cortisol levels, and balances stress responses .
Migraine & Health Management: Emerging studies suggest potential benefits in migraine prevention and hormonal balance .

Product Highlights

Purity & Safety: Free from additives, preservatives, GMOs, allergens, and hazardous substances (OSHA/GHS non-hazardous) .
Global Compliance: Meets USP, European Pharmacopoeia standards, and certifications from TSCA, REACH, and ISO .
Versatile Applications: Suitable for capsules, tablets, creams, sprays, and custom OEM/ODM formulations .
Stability: Shelf life up to 8 years when stored in dry conditions at -20°C .

Technical Specifications

Molecular Formula: C₁₃H₁₆N₂O₂
Molecular Weight: 232.28
Melting Point: 116.5–118°C
Solubility: Ethanol (50 mg/mL), water-insoluble
Testing Methods: HPLC, UV/IR spectroscopy, microbial analysis (E. coli, Salmonella-free) .

Usage Guidelines

Dosage: Typical adult dose ranges from 0.5–5 mg daily, taken 30–60 minutes before bedtime. Consult a healthcare provider for personalized advice.
Precautions: Avoid during pregnancy, breastfeeding, or autoimmune conditions. May cause mild side effects (e.g., dizziness, daytime drowsiness)

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Melatonin