Product Name:Synephrine 98%
Botanical Source:Citrus Aurantium extract
Part: Fruit
Extraction Method: Water/ Grain Alcohol
Form:White to off-white fine powder
Specification: 95%
Test Method : HPLC
CAS NO:94-07-5
GMO Status:GMO Free
Packing: in 25kgs fiber drums
Storage:Keep container unopened in cool, dry place,Keep away from strong light
Shelf Life:24 months from date of production
Product Title: Synephrine 98% HCl | Natural Citrus Aurantium Extract | Thermogenic Fat Burner & Adrenergic Agonist
Product Overview
Synephrine Hydrochloride (98% purity, CAS 5985-28-4) is a naturally derived α-adrenergic and β-adrenergic agonist extracted from Citrus aurantium (bitter orange). Structurally similar to ephedrine alkaloids, it offers sympathomimetic effects while being a safer alternative for weight management and energy enhancement . Widely used in dietary supplements, Synephrine 98% is a key ingredient in thermogenic formulations to boost metabolism and calorie expenditure .
Key Features
- High Purity & Quality:
- Purity: ≥98% (HPLC-verified) .
- CAS No.: 5985-28-4 (Synephrine HCl) | 94-07-5 (Synephrine base).
- Molecular Formula: C₉H₁₄ClNO₂ .
- Appearance: White to off-white crystalline powder, water-soluble .
- Natural Source & Safety:
- Derived from Citrus aurantium, a plant traditionally used in Chinese medicine for appetite regulation .
- Clinically studied for mild thermogenic effects (e.g., 50 mg dose increases calorie burn by 65 kcal over 75 minutes) without significant side effects .
- Mechanism of Action:
- Acts as a partial agonist for α1A-adrenergic receptors (EC₅₀ = 4 μM) and antagonist for α2A/α2C receptors .
- Enhances glucose metabolism in skeletal muscles and reduces portal hypertension in animal models .
Applications
- Weight Management: Promotes fat oxidation and thermogenesis when combined with bioflavonoids (e.g., naringin or hesperidin) .
- Energy & Focus: Stimulates sympathetic nervous system activity, improving endurance and cognitive performance .
- Research Use: Ideal for studying adrenergic pathways, metabolic disorders, and cardiovascular effects .
Usage Guidelines
- Recommended Dosage: 20–50 mg/day (as part of a blend; consult formulation guidelines) .
- Solubility: Soluble in water, DMSO (31 mg/mL), and ethanol (2 mg/mL) .
- Synergistic Combinations: Pair with naringin (600 mg) or hesperidin (100 mg) for enhanced calorie-burning effects .
Safety & Compliance
- Hazard Class: 9 (Packing Group III) – Store at -20°C in dry conditions .
- Safety Notes:
- Avoid contact with skin/eyes; use gloves and protective gear during handling .
- Compliant with FDA regulations for dietary ingredients (avoid NDIs; ≤30% synephrine in extracts) .
- Label accuracy ensured (tested via HPLC/PRM methods) .
Packaging & Storage
- Powder: 100g–1kg sealed bags; stable for 3 years at -20°C .
- Solution: Dissolved in solvent (e.g., DMSO), store at -80°C for 1 year .
Why Choose Our Synephrine 98%?
- Certified Authenticity: Sourced from Citrus aurantium with traceable botanical origin .
- Research-Backed: Validated in vivo studies for efficacy in metabolic and cardiovascular research .
- Keywords: “Natural Fat Burner,” “Thermogenic Supplement,” “Bitter Orange Extract,” “Adrenergic Agon
