I-Garlic inotyebi kwiikhompawundi ezinesulfure, eziye zaboniswa ukubonisa iimpawu zokukhuthaza impilo kunye nokukhusela izifo kwiintlobo ezininzi ze-vitro kunye ne-vivo studies.i-garlic extract Ezi zakhiwo ziquka i-antioxidant, i-anti-inflammatory, kunye ne-lipid-downing effects, njengoko kunye nemisebenzi ye-antiviral kunye ne-antineoplastic. Kwakhona kuye kwaboniswa ukunciphisa uxinzelelo lwegazi kunye namanqanaba e-cholesterol.
I-Allicin, i-ajoene, kunye ne-thiocyanates iboniswe ukuba inqanda ukuhlanganiswa kwezinto ezinobungozi kuzo zombini iibhaktheriya zegram-positive (i-S.garlic extract epidermidis) kunye ne-gram-negative bacteria (P. aeruginosa PAO1). Ukongezelela, i-garlic extract yafunyanwa ukukhusela ukubunjwa kwe-biofilm kunye nokubambelela kwi-S. epidermidis strains kunye nokunciphisa i-bacterial virulence kwi-P. aeruginosa PAO1 i-strains ngokuthintela inkqubo ye-quorum sensing system (QS) elawula le miba ye-virulence.
Uphando luye lwabonisa ukuba isongezelelo semihla ngemihla ye-garlic extract (AGE) inokunceda ukunciphisa amanqanaba e-cholesterol, ngakumbi kubantu abakhulu kakhulu okanye abanesifo sikashukela.i-garlic extract Kwisifundo esinye, abo bathatha i-AGE kwiiveki ze-6 bafumana ukunciphisa amanqanaba e-triglyceride kwaye amanqanaba e-cholesterol e-HDL aphuculweyo. I-AGE iphinde yanciphisa izilonda ze-atherosclerotic kwimibhobho yezigulane ezine-atherosclerosis, ngokutsho kophando lwe-2004 olupapashwe kwi-Journal of Nutritional Biochemistry.
I-organosulfur compounds kwi-AGE inokuthintela iintsholongwane ukuba zingene kwiiseli zethu kwaye ziphindaphinde, ngokutsho kohlaziyo lwe-2020 olupapashwe kwi-Trends in Food Science & Technology.i-garlic extract Enyanisweni, abaphandi bafumanisa ukuba i-AGE supplements inokuthintela ukubanda kunye nomkhuhlane ngokunyusa amajoni ethu omzimba. .
Kwimeko yomhlaza, uphando lubonise ukuba i-alyl sulfide kunye ne-diallyl disulfuride (DADS) kwi-AGE inokuthintela ukukhula kwe-tumor kunye nokucinezela i-angiogenesis, inkqubo apho amathumba ahlaselayo aphuhlisa imithambo yegazi emitsha ukutshisa ukukhula kwabo ngokukhawuleza.i-garlic extract DADS nayo kuboniswe ukuba kubangele iSigaba sesi-II sokukhupha i-enzymes kwiiseli zomhlaza webele.
Enye inzuzo yezempilo ye-AGE kukukwazi ukunyusa ukunyanzeliswa kwengcinezelo ye-oxidative yeeseli zesibindi somntu, ngokutsho kophando lwe-2014 olupapashwe kwiphephancwadi elithi "Nutrients." Ukongezelela, kuye kwangqinwa ukuba kuthintelwe ukunyuswa kwamafutha kunye nokuphucula umsebenzi we-mitochondria yesibindi.
Ekugqibeleni, i-AGE ibonakaliswe ukuphucula ukusebenza kwezemidlalo kubantu ngokunyusa umthamo wamandla okuveliswa yimizimba yethu. Oku kufezekiswa ngokunciphisa ukubonakaliswa kwezakhi zofuzo ezilawula i-fatty acid synthesis kunye nokuphucula i-thermogenesis, ekugqibeleni ikhokelela kumthamo omkhulu wokuzilolonga.
I-sulforaphane kunye ne-allyl isothiocyanates kwi-AGE zikwakholelwa ukuba zikhusela i-osteoarthritis ngokunciphisa ukophuka kwamathambo. Oku kungenxa yokuba i-sulforaphane kunye ne-LYS zivimba i-enzyme glucosidase, enoxanduva lokuphula izicubu ezixhumeneyo. Oku, kwakhona, kunciphisa ukuphuhliswa kweekhemikhali ezivuthayo ezibangela intlungu kunye nokuqina kwamalungu. Ukongeza, i-LYS inokunceda ukuqinisa amathambo ngokukhuthaza ukuveliswa kwe-collagen kunye nokuthintela ukuwohloka kwesakhiwo samathambo. Okokugqibela, i-LYS inokuphucula ukuhamba kwegazi kwindawo edibeneyo. Oku kubalulekile ukuthintela okanye ukulibazisa ukuqala kwe-osteoarthritis. Oku kungenxa yokuba i-osteoarthritis ibonakala ngokunyuka kokuvuvukala kwamalungu. Oku kungenxa yokuba izinto ezivuthayo ezifana ne-cytokines kunye ne-prostaglandins zinokuphazamisa umsebenzi oqhelekileyo odibeneyo.
Ixesha lokuposa: Apr-08-2024