I-MADRID, ngoFebruwari 1, 2022 / PRNewswire / - I-Garlic emnyama ekhulile (ABG +®), imveliso ye-biotechnology ye-pharmaceutical, i-SLU, ibonise amandla amatsha anenzuzo yokulinganisa uxinzelelo lwegazi kwisifundo esitsha seklinikhi kubantu abanezinga eliphezulu le-cholesterol ephezulu.I-ABG+ ikhuliswe kwaye ilinywe ekuhlaleni, iiyure nje ezimbini ukusuka kwiziko loxubo mayeza, kwaye icutshungulwe ngononophelo kusetyenziswa itekhnoloji ehambelana nokusingqongileyo.Le nkqubo ivelisa inkunkuma encinci kwaye inciphisa kakhulu impembelelo yokusingqongileyo.
Olu phononongo olungenamkhethe, oluyimfama oluphindwe kabini, oluqhubekayo, olulawulwa ngokunqamlezayo lwapapashwa kwiphephancwadi lezenzululwazi I- Nutrition ngoJanuwari 18, 2022 [1] kwaye lwenziwa kwiSibhedlele seYunivesithi yaseSant Joan de Reus e-Barcelona.Uphononongo, olukhokelwa nguGqr. Rosa Walls, umbhali wamaphepha enzululwazi angaphezu kwe-150 kunye nomphathi weqela leethisisi zobugqirha, libandakanya amavolontiya amadala angama-67 ane-hypercholesterolemia kunye namanqanaba aphezulu e-LDL yegazi.Umthathi-nxaxheba ngamnye ufumene i-250 mg ye-ABG + okanye i-placebo kwiiveki ezintandathu, kunye nexesha leeveki ezintathu zokuhlamba ngaphambi kokutshintsha.Izifundo zikwamiselwe ukutya okungabandakanyi i-lipid-ukwehlisa kunye neemveliso ze-antihypertensive.
Iziphumo zeeveki ezintandathu zibonise ukuba i-ABG + isicatshulwa sinciphisa kakhulu uxinzelelo lwegazi lwe-diastolic (DBP) ngomlinganiselo we-5.85 mmHg.xa kuthelekiswa ne-placebo.Le ntsabelo intle yachazwa ngokukhethekileyo emadodeni.U-Alberto Espinel, iNtloko yoPhando kunye noPhuhliso kwi-Pharmaactive, wachaza: "Ukunciphisa uxinzelelo lwegazi lwe-diastolic nge-5 mmHg kuphela.Ubugcisa.inokunciphisa ngokuphawulekayo ingozi yestroke nezinye izifo zemithambo-luvo.”
Uxinzelelo lwegazi oluphezulu luchaphazela phantse isinye kwisithathu sabantu abadala kwihlabathi liphela kwaye yeyona nto inobungozi obunokuthinteleka kwisifo sentliziyo kunye nokubhubha kwabantu.Phakathi kwabantu abaneminyaka engama-40 ukuya kwi-89 iminyaka, ukwanda kwe-diastolic yegazi kwi-10 mm Hg.Ubugcisa.iphindaphindeke kabini ingozi eyayanyaniswa nesifo esiqhelekileyo se-cardiovascular and stroke.
Olu luphononongo lokuqala lweklinikhi olwenzelwe i-ABG +, ukwakha kwiziphumo ezikhuthazayo ezivela kwizifundo zezilwanyana ezimbini zangaphambili zenkampani.Olu vavanyo lubonise iziphumo zesithako se-cardioprotective kunye nokukwazi ukulinganisa ngokufanelekileyo iilipids zegazi kunye nokuphucula ukusebenza kwemithambo yegazi.
"Ikonofile emnyama esele ikhulile kudala ithathwa njengento emnandi kwaye iyinxalenye yokutya kwase-Asia, kunye neyomeleza impilo," utshilo u-Aspinell."Ubungqina obunobungqina bubonisa imiphumo emihle yegalikhi emnyama kwimpilo yenhliziyo.Nangona kunjalo, ubukhulu bempembelelo buxhomekeke kwisixa kunye nohlobo lwee-compounds eziqokelelwe ngexesha lokuguga, kunye nokukwazi ukukhupha nokugcina ezi zixhobo ngexesha lokucubungula.
Esi sithako simnandi ngokwesiko senziwe ngokugcina iiglowubhu ezipheleleyo zegalikhi entsha yaseSpain kumswakama ophezulu kunye nobushushu kangangeeveki ezininzi.Amagaqa egalikhi aba mnyama kwaye athambile, afana nejeli, aphulukane nencasa yawo enesiqholo yekonofile njengoko esiba mnandi.Ngethuba le nkqubo, ibhalbhu endala ifumana utshintsho olubalulekileyo lwe-biochemical.Iingqungquthela eziphambili ze-organosulfur, i-alliin kunye ne-allicin, ziye zancitshiswa kwigalikhi entsha.Nangona kunjalo, i-bioactive complex complex ye-polyphenols enyibilikayo (ikakhulukazi i-PAA, i-flavonoids kunye ne-melanoids) yayiphakanyiswe kakhulu.I-synergy yezi antioxidants ithathwa njengowona mthombo we-ABG + ye-cardioprotective properties.
Isicatshulwa se-Pharmaactive ABG + sisemgangathweni kwi-1.25 mg S-allyl-L-cysteine (SAC) polyphenols.Iveliswa kusetyenziswa itekhnoloji yokuguga yenkampani ye-ABG Cool-Tech®.Uxinzelelo lwe-SAC olutyebileyo lwaqinisekiswa yi-HPLC (ulwelo oluphezulu lwechromatography).
“I-SAA ayikho kwigalikhi entsha, kodwa iyadityaniswa ize iqokelelwe xa ivuthiwe phantsi kweemeko ezithile zokusingqongileyo,” ucacise watsho u-Espinel.“Ubukho kunye nokuxinana kwezinto ezisebenzayo kuxhomekeke kakhulu kwinkqubo yokwenziwa kwemveliso.Uninzi lweemveliso zegalikhi ezimnyama kwintengiso zisetyenziselwa kuphela iipropathi zabo zokupheka kwaye ziqulethe i-SAC encinci okanye ayikho.Kwezinye iimeko, i-SAC ifumaneka kwigalikhi ngokusebenzisa inkqubo ende yoshishino ebandakanya ukucwiliswa kwee-bulbs kwi-solvents eziphilayo, umphumo ubhalwe nje "i-garlic endala".Oku kubeka esichengeni umxholo we-bioactive, kwaye apho izifundo ezikhoyo kwiincindi zegalikhi ezimnyama zibonise iziphumo eziphikisanayo kwaye zibangele umsebenzi ophilileyo. "
"Obu bubungqina bokuqala bempembelelo yokulinganisa uxinzelelo lwegazi lwe-ABG + isicatshulwa njengenye indlela yendalo yabantu abanezicwangciso zabo zokungenelela zisekelwe kwisondlo kunye nokugcinwa kwendlela yokuphila enempilo," waqhubeka u-Espinel."Okubalulekileyo, iziphumo zayo ezilungileyo zifezekiswa ngokuthatha ithebhulethi enye ye-ABG + isicatshulwa ngosuku."
"Uphando lweklinikhi lwexesha elizayo luya kugxininisa amandla okulawula uxinzelelo lwegazi lwe-ABG + yethu isicatshulwa," wongeza uJulia Diaz, iNtloko yeNtengiso, i-Pharmaactive.“Ukhetho lwendlela yokuphila, kubandakanywa neerejimeni zokutya ezifana ne-DASH okanye ukutya kweMeditera, lunyango lokuqala lokucotha nokuthintela uxinzelelo lwegazi oluphezulu.I-ABG+ sesinye isixhobo esinesondlo esisebenzayo nesinencasa ukunceda ukulawula uxinzelelo lwegazi, ngakumbi abo banoxinzelelo lwegazi oluphezulu.Phakathi kwezigulane ezinoxinzelelo lwe-arterial.Abo banengxaki yokulandela imiqathango yokutya. ”
Zonke izithako ze-ABG + zinyibilika emanzini kwaye zinokusetyenziswa kwizicelo ezahlukeneyo ezibandakanya iintsini, iipilisi, iigels ezithambileyo, iisyrups kunye nomgubo.Ngaphandle kwevumba elibonakalayo kunye nencasa yegalikhi, izithako ze-ABG + zifanelekile kukutya okusebenzayo kunye nokuhlafuna iintsini.
IiMveliso ze-Pharmaactive Biotech (SLU) yinkampani enguvulindlela esekwe eMadrid ephuhlisa kwaye yenze izinto ezahlukeneyo zendalo ezisekwe kwisayensi ezifana nesafron ecocekileyo kunye negalikhi emnyama endala.Injongo yale nkampani kukwenza impembelelo entle nebalulekileyo kwimpilo yabantu nakwintlalontle ngokusetyenziswa kwezithako zamayeza ezikumgangatho ophezulu, ezixhaswa luphando lwezenzululwazi kwaye zivunywe ziikomiti zokuziphatha.Iyakhula, ihlakulele kwaye ivelise imathiriyeli ekrwada esekwe kwizityalo ukusuka kwifama ukuya kwifolokhwe enempembelelo yokusingqongileyo ephantsi.
UQhagamshelwano lweNkampani: IiMveliso ze-Pharmaactive Biotech, SLU Eva Criado, uMphathi wezoBudlelwane boLuntu uMnxeba: +34 625 926 940 I-imeyile: [i-imeyile ekhuselweyo] Twitter: @Pharmactive_SPWeb: www.pharmaactive.eu
Uqhagamshelwano lwemidiya: NutriPR Liat Simha Ifowuni: +972-9-9742893 I-imeyile: [i-imeyile ekhuselweyo] Twitter: @NutriPR_Web: www.nutripr.com
Ixesha lokuposa: Aug-21-2023