10-Deacetylbaccatin III (10-DAB)

Apejuwe kukuru:

10-Deacetylbaccatins jẹ lẹsẹsẹ adayeba ti o ni ibatan pẹkipẹkiOrganic agboti o ya sọtọ si igi yew (GeneraTaxis). 10-Deacetylbaccatin III jẹ iṣaju si oogun egboogi-akàndocetaxel(Taxotere).

10-deacetylbaccatin III 10-O-Acetyltransferaseṣe iyipada 10-deacetylbaccatin sibaccatin III:

10-Deacetylbaccatin III, ti a tun mọ ni 10-DAB tabi 10-DAB III, jẹ awọn agbo ogun Organic ti o ni ibatan pẹkipẹki ti o ya sọtọ lati awọn abere gbigbe ati awọn ẹka kekere ti igi yew ti Yuroopu (Taxus baccata) .10-Deacetylbaccatin III jẹ iṣaaju si oogun egboogi-akàn docetaxel (Taxotere). pacitaxel (taxol); cabazitaxel. 10-10-deacetylbaccatin III ni a rii ni yiyan lati dena idagba ti L. DONOVANI intracellular amastigotes laarin J774 murine macrophages in vitro ni awọn ifọkansi nanomolar pẹlu iye IC (50) ti 70 nM.

Iye owo FOB:US $0.5 - 2000 / KG

Iye Ibere Min.1 KG

Agbara Ipese:10000 KG fun oṣu kan

Ibudo:SHANGHAI/BEIJING

Awọn ofin sisan:L/C,D/A,D/P,T/T

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ọja Tags

Orukọ kemikali:	10-Deacetylbaccatin III
Nọmba CAS:	32981-86-5
Awọn itumọ ọrọ sisọ:	10-Desacetylbaccatin III; 10β-Deacetylbaccatin III; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy) -1,2a,3,4,4a,6,9,10,11, 12,12a,12b-dod ecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca [3,4] benz [1,2-b] oxet-5-ọkan; 7,11-Methano-5H-cyclodeca [3,4] benz [1,2-b] oxet-5-ọkan, 12b- (acetyloxy) -12- (benzoyloxy) -1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a, 8,13,13-tetramethyl-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-; (Docetaxel USP aimọ);10-Deacetylbaccatin III; 10-Deacetyl baccatin; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-1,2a,3,4,4a,6,9,10,11,12,12a, 12b-Dodecahydro-4,6,9,11,12,12b-hexahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4] benz [1,2-b] oxet-5-ọkan 12b-acetate, 12-benzoate (USP);
Fọọmu molikula:	C29H36O10
Ìfarahàn:	White Ri to
Mol. Ìwúwo:	544.6
Ibi ipamọ:	2-8 ° C firiji