L-ERGOTHIONEINE 99% BY HPLC
Antioxidant Ere fun Nutraceutical & Awọn ohun elo Kosimeceutical
1. ọja Akopọ
L-Ergothionine(ERT) jẹ amino acid ti o ni imi-ọjọ imi-ọjọ ti o nwaye lati inu bakteria microbial, ni akọkọ ti a rii ninu awọn olu gẹgẹbiTricholoma matsutakeatiHericium erinaceus. Ọja wa jẹ mimọ-giga (≥99% nipasẹ HPLC) lulú crystalline pẹlu CAS No.. 497-30-3, ti a fọwọsi nipasẹ itupalẹ chromatographic lile. O ṣe afihan iduroṣinṣin alailẹgbẹ ni awọn ilana pH 4.0-6.0, ti o jẹ ki o jẹ apẹrẹ fun awọn iṣan ara, awọn ipara, ati awọn afikun ẹnu.
Awọn ẹya pataki:
- Mimo: ≥99% (ifọwọsi HPLC, COA ti o ni ipele ti a pese)
- Fọọmu Molecular: C₉H₁₅N₃O₂S | Iwọn Molecular: 229.3 g/mol
- Solubility: 125 miligiramu / milimita ninu omi (iranlọwọ ultrasonic)
- Awọn iwe-ẹri: ti kii ṣe GMO, Ọfẹ Ẹhun, Ajewebe-Ọrẹ
2. Iṣakoso Didara & Ilana HPLC
Ilana itupalẹ wa ni ibamu pẹlu awọn ilana atunyẹwo ẹlẹgbẹ:
- Apeere Igbaradi: 1 milimita asa alabọde sise ni 94 ° C fun 10 min, vortexed (1600 rpm / 30 min), centrifuged (10,000 × g / 5 min), ati ti o fipamọ ni -20 ° C ti o ba nilo.
- Eto HPLC: Dionex Ultimate 3000 pẹlu sọfitiwia Chromeleon.
- Ọwọn: Cortecs UPLC T3 (2.1×150 mm, 1.6 μm patikulu, 120 Å pore iwọn) .
- Ipele Alagbeka: elution gradient lati 0.1% formic acid si 70% acetonitrile/0.1% formic acid, oṣuwọn sisan 0.3 mL/min.
- Wiwa: gbigba UV ni 254 nm, LOQ 0.15 mmol/L.
Awọn Metiriki Afọwọsi:
- Laini ila: 0.3–10 mmol/L (R²>0.99)
- Ipese: ≤6% RSD (intra-/inter-assay)
- Imularada: ~ 100% deede
3. Awọn anfani Ilera & Awọn ohun elo
3.1 Nutraceutical Ipawo
- Mitochondrial Idaabobo: Din wahala oxidative nipa scavenging hydroxyl radicals (IC₅₀: 2.5 μM) ati superoxide anions.
- Atilẹyin Telomere: Idaduro telomere ti o ni ibatan ọjọ-ori ni kikuru ni vitro .
- Iwọn lilo: Awọn ijinlẹ ile-iwosan daba 5-20 mg / ọjọ gbe awọn ipele ERT pilasima ga ni pataki.
Awọn ọja ti a ṣe iṣeduro:
- Awọn agunmi: 100 μg–5 mg fun iṣẹ kan (fun apẹẹrẹ, Awọn ọdọ Pataki ti LifeExtension) .
- Awọn idapọmọra Amuṣiṣẹpọ: Darapọ pẹlu ferulic acid fun imudara bioavailability.
3.2 Cosmeceutical Lilo
- Anti-Aging: Idilọwọ tyrosinase (40% idinku ni 0.5% ifọkansi) ati aabo fun elastin lati ibajẹ UV.
- Awọn Itọsọna Ilana:
- pH: 4.0-6.0 (iduroṣinṣin ti o dara julọ)
- Ifojusi: 0.5-2.0% ni awọn omi ara / lotions
- Ibamu: Iduroṣinṣin pẹlu Vitamin C, hyaluronic acid, ati peptides.
4. Imọ ni pato
| Paramita | Sipesifikesonu | Itọkasi |
|---|---|---|
| Ifarahan | Funfun okuta lulú | |
| Mimọ (HPLC) | ≥99% | |
| Ojuami Iyo | 275–280°C (dibajẹ) | |
| Ibi ipamọ | 2-8 ° C ninu apo eiyan afẹfẹ | |
| Igbesi aye selifu | osu 24 |
5. Aabo & Ilana Ilana
- Data Abo: LD₅₀>2000 mg/kg (ẹnu, eku); ko si awọn ipa buburu ninu awọn idanwo eniyan.
- Awọn iwe-ẹri: Afọwọsi Ounjẹ aramada EU (Ergoneine®), FDA GRAS.
- Mimu: Lo awọn atẹgun ti a fọwọsi NIOSH ati awọn ibọwọ sooro kemikali lakoko sisẹ ile-iṣẹ.
6. Agbaye Ipese & Iṣakojọpọ
- Awọn aṣayan Iṣakojọpọ: 1 kg, 10 kg, 1000 kg (awọn apo apamọwọ aluminiomu pẹlu desiccant) .
- Akoko asiwaju: Awọn ọjọ iṣowo 3–5 (sowo agbaye nipasẹ DHL/FedEx) .
- Awọn ọja Sin: USA, EU, Australia, Japan, Brazil.
7. Koko Ọrọ
- Awọn ọrọ-ọrọ: "L-Ergothioneine 99%HPLC”, “Olupese Antioxidant Adayeba”, “Ergothioneine fun Itọju Awọ”.
- Pẹlu CAS 497-30-3, awọn ẹtọ mimọ, ati awọn ofin ohun elo.
