I-Glutathioneiyi-antioxidant ekhona ngokwemvelo emzimbeni.Eyaziwa nangokuthi i-GSH, ikhiqizwa amangqamuzana ezinzwa esibindini nasesimisweni sezinzwa esimaphakathi futhi sakhiwe ama-amino acid amathathu: i-glycine, i-L-cysteine, ne-L-glutamate.I-Glutathione ingasiza ekuhlanganiseni ubuthi, iphule ama-radicals mahhala, isekele umsebenzi wokuzivikela komzimba, nokuningi.
Lesi sihloko sidingida i-antioxidant glutathione, ukusetshenziswa kwayo, kanye nezinzuzo okuthiwa.Iphinde inikeze izibonelo zendlela yokwandisa inani le-glutathione ekudleni kwakho.
E-United States, izithasiselo zokudla zilawulwa ngendlela ehlukile kunezidakamizwa.Lokhu kusho ukuthi i-Food and Drug Administration (FDA) ayigunyazi imikhiqizo ngokuphepha nokusebenza kwayo kuze kube yilapho isisemakethe.Noma nini lapho kunokwenzeka, khetha izithasiselo ezihlolwe inkampani yangaphandle ethembekile njenge-USP, ConsumerLab, noma i-NSF.Kodwa-ke, ngisho noma izithasiselo zihlolwa ngumuntu wesithathu, lokhu akusho ukuthi ziphephile kuwo wonke umuntu noma zisebenza ngokujwayelekile.Ngakho-ke, kubalulekile ukuxoxa nganoma yiziphi izithasiselo ohlela ukuzithatha nomhlinzeki wakho wokunakekelwa kwezempilo futhi uhlole ukuthi kungenzeka yini ukuxhumana nezinye izithasiselo noma imithi.
Ukusetshenziswa kwezithako zokudla kufanele kube okomuntu oyedwa futhi kuqinisekiswe uchwepheshe wezokunakekelwa kwempilo njengodokotela wezokudla obhalisiwe, usokhemisi, noma umhlinzeki wokunakekelwa kwezempilo.Asikho isithako esihloselwe ukwelapha, ukwelapha, noma ukuvimbela izifo.
Ukuncipha kwe-glutathione kukholakala ukuthi kuhlotshaniswa nezimo ezithile zempilo ezifana nezifo ze-neurodegenerative (njenge-Parkinson's disease), i-cystic fibrosis, nezifo ezihlobene nobudala kanye nenqubo yokuguga.Kodwa-ke, lokhu akusho ukuthi izithasiselo ze-glutathione zizosiza ngempela kulezi zimo.
Kodwa-ke, kunobufakazi obulinganiselwe besayensi obusekela ukusetshenziswa kwe-glutathione ukuvimbela noma ukwelapha noma yisiphi isimo sezempilo.
Ucwaningo lubonisa ukuthi i-glutathione ehogeliwe noma yomlomo ingasiza ukuthuthukisa ukusebenza kwamaphaphu nesimo sokudla okunempilo kubantu abane-cystic fibrosis.
Ukubuyekezwa okuhlelekile kuhlolwe ucwaningo ngomphumela wama-antioxidants kubuthi obuhlobene ne-chemotherapy.Izifundo eziyishumi nanye ezihlaziywe zibandakanya izithasiselo ze-glutathione.
I-Intravenous (IV) glutathione ingasetshenziswa ngokuhambisana nokwelashwa ngamakhemikhali ukuze kwehliswe imiphumela enobuthi ye-chemotherapy.Kwezinye izimo, lokhu kungase kwandise amathuba okuqeda inkambo ye-chemotherapy.Kudingeka ucwaningo olwengeziwe.
Ocwaningweni olulodwa, i-glutathione efakwa emthanjeni (600 mg kabili ngosuku izinsuku ezingama-30) yathuthukisa kakhulu izimpawu ezihambisana nesifo sikaParkinson esasingelashiwe ngaphambili.Nokho, ucwaningo lwaluluncane futhi luhlanganisa iziguli eziyisishiyagalolunye kuphela.
I-Glutathione ayithathwa njengesakhi esibalulekile ngoba ikhiqizwa emzimbeni kusuka kwamanye ama-amino acid.
Ukudla okungalungile, ubuthi bemvelo, ukucindezeleka, nokuguga konke kungaholela emazingeni aphansi e-glutathione emzimbeni.Amazinga aphansi e-glutathione ahlotshaniswa nengozi eyengeziwe yomdlavuza, isifo sikashukela, isifo sokusha kwesibindi kohlobo nesifo sikaParkinson.Nokho, lokhu akusho ngempela ukuthi ukwengeza i-glutathione kuzonciphisa ingozi.
Njengoba izinga le-glutathione emzimbeni lingavamile ukulinganiswa, kunolwazi oluncane mayelana nokuthi kwenzekani kubantu abanamazinga aphansi e-glutathione.
Ngenxa yokuntuleka kocwaningo, kuncane okwaziwayo ngemiphumela emibi yokusebenzisa izithasiselo ze-glutathione.Ayikho imiphumela emibi eye yabikwa ngokuthathwa okuphezulu kwe-glutathione ekudleni kuphela.
Kodwa-ke, kukhona ukukhathazeka ukuthi ukusetshenziswa kwe-glutathione supplements kungase kubangele amajaqamba, ukuqunjelwa, noma ukungezwani nezimpawu ezifana nokuqubuka.Ngaphezu kwalokho, ukuhogela i-glutathione kungabangela izinkinga zokuphefumula kwabanye abantu abanesifuba somoya esithambile.Uma kwenzeka noma yimiphi yale miphumela engemihle, yeka ukuthatha isithasiselo bese uxoxa ngaso nomhlinzeki wakho wezempilo.
Ayikho idatha eyanele yokubonisa ukuthi iphephile kubantu abakhulelwe noma abancelisa ibele.Ngakho-ke, izithako ze-glutathione azinconywa uma ukhulelwe noma uncelisa.Hlala uthintana nochwepheshe wakho wezempilo ngaphambi kokuthatha noma yiziphi izithasiselo.
Imithamo eyahlukene iye yacwaningwa ocwaningweni oluqondene nezifo ezithile.Umthamo okulungele ungancika ezintweni eziningi, okuhlanganisa iminyaka yakho, ubulili, nomlando wezokwelapha.
Ezifundweni, i-glutathione yanikezwa ngemithamo esukela ku-250 kuya ku-1000 mg ngosuku.Ucwaningo olulodwa lwathola ukuthi okungenani i-500 mg ngosuku okungenani amasonto amabili yayidingeka ukuze kwandiswe amazinga e-glutathione.
Ayikho idatha eyanele yokwazi ukuthi i-glutathione isebenzisana kanjani nemithi ethile nezinye izithasiselo.
Qiniseka ukuthi ulandela imiyalelo yomkhiqizi yokuthi ungasigcina kanjani isithasiselo.Kungase kwehluke kuye ngohlobo lwesithasiselo.
Ngaphezu kwalokho, ukugcwalisa nezinye izakhi kungasiza ekwandiseni ukukhiqizwa komzimba kwe-glutathione.Lokhu kungase kuhlanganise:
Gwema ukuthatha i-glutathione uma ukhulelwe noma uncelisa.Ayikho idatha eyanele yokusho ukuthi iphephile ngalesi sikhathi.
Kodwa-ke, ezinye zalezi zinkinga zingase zihlotshaniswe nendlela yokufakwa kwe-intravenous engafanele noma i-glutathione mbumbulu, kusho abacwaningi.
Noma yisiphi isengezo sokudla akufanele sihloselwe ukwelapha isifo.Ucwaningo nge-glutathione ku-Parkinson's disease lulinganiselwe.
Kolunye ucwaningo, i-glutathione efakwa emthanjeni yenza ngcono izimpawu zesifo sikaParkinson sokuqala.Nokho, ucwaningo lwaluluncane futhi luhlanganisa iziguli eziyisishiyagalolunye kuphela.
Olunye uhlolo lomtholampilo olungahleliwe luphinde lwathola ukuthuthuka ezigulini ezinesifo sika-Parkinson ezithole imijovo ye-glutathione emakhaleni.Nokho, ayizange isebenze kangcono kune-placebo.
I-glutathione itholakala kalula kokunye ukudla okufana nezithelo nemifino.Ucwaningo olwanyatheliswa kumagazini i- Nutrition and Cancer luthole ukuthi imikhiqizo yobisi, okusanhlamvu, nesinkwa ngokuvamile kune-glutathione encane, kuyilapho izithelo nemifino kulinganiselwe kuya phezulu ku-glutathione.Inyama esanda kuphekwa inothe nge-glutathione.
Iyatholakala futhi njengesengezo sokudla njengama-capsules, uketshezi, noma ifomu le-topical.Ingabuye inikezwe ngomjovo.
Izithasiselo ze-Glutathione nemikhiqizo yokunakekelwa komuntu siqu iyatholakala ku-inthanethi nasezitolo eziningi zokudla zemvelo, amakhemisi, nezitolo zamavithamini.Izithako ze-Glutathione zitholakala kuma-capsules, uketshezi, ama-inhalants, i-topical noma i-intravenous.
Vele uqiniseke ukuthi ubheka izithasiselo ezihlolwe yizinkampani zangaphandle.Lokhu kusho ukuthi isengezo sihloliwe futhi siqukethe inani le-glutathione elishiwo kulebula futhi ayinakho ukungcola.I-USP, i-NSF, noma izithasiselo ezinelebula ze-ConsumerLab zihloliwe.
I-Glutathione idlala izindima eziningana emzimbeni, okuhlanganisa isenzo sayo se-antioxidant.Amazinga aphansi e-glutathione emzimbeni ahlotshaniswa nezimo eziningi ezingapheli kanye nezifo.Kodwa-ke, akubanga khona ucwaningo olwanele lokwazi ukuthi ukuthatha i-glutathione kunciphisa ingozi yalezi zifo noma kunikeza izinzuzo zezempilo.
I-Glutathione ikhiqizwa emzimbeni kusuka kwamanye ama-amino acid.Ikhona nasekudleni esikudlayo.Ngaphambi kokuba uqale ukuthatha noma yisiphi isithasiselo sokudla, qiniseka ukuthi uxoxa ngezinzuzo nezingozi zesengezo nomhlinzeki wakho wezempilo.
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Umbhali: U-Jennifer Lefton, MS, RD/N, CNSC, FAND Jennifer Lefton, MS, RD/N-AP, CNSC, FAND uyi-Dietitian/ Nutritionist Ebhalisiwe kanye nombhali oneminyaka engaphezu kwengu-20 yesipiliyoni sokudla okunempilo.Ulwazi lwakhe lusukela ekwelulekeni amaklayenti ngokuvuselelwa kwenhliziyo kuye ekulawuleni izidingo zokudla okunomsoco ezigulini ezihlinzwa kanzima.
Isikhathi sokuthumela: Jul-20-2023