Ukuzivikela komzimba kuwukuphela kwesithiyo esiqinile empilweni yomzimba.Amasosha omzimba asebenza “njengebutho” emzimbeni, elwa “nesitha” esibeka impilo yethu engcupheni nsuku zonke, kodwa isikhathi esiningi asizizwa.Le “mpi” enzima ingoba leli “qembu” linenzuzo ngokuphelele.Uma ukuzivikela komzimba kuphukile, umzimba wethu "uzodiliza" futhi uchungechunge lwezifo luzovela, olungagcini nje ngokubeka ingcindezi kumuntu ngamunye, kodwa futhi luthwalisa umndeni.Ukuphindwaphindwa kwesifo esisha somqhele kuphinde kwaqinisekisa ukubaluleka kokuzivikela komzimba womuntu.Ucwaningo oluningi luye lwaqinisekisa ukuthi i-ginsenoside CK yenze impumelelo enkulu ekulawuleni ukuzivikela komzimba womuntu futhi iphumelele ukuphuma emakethe yokudla yezempilo.
E-China, i-ginseng ibilokhu ibhekwa njengenkosi yezitshalo futhi yaziwa ngokuthi "i-ejenti engcono kakhulu yokondla nokuqinisa eMpumalanga".ENtshonalanga, i-ginseng ibizwa nge-PANAX CA MEYERGINSENG, "PANAX" isuka kwelesiGrikhi, okusho ukuthi "ukwelapha zonke izifo", kanti "GINSENG" yindlela yokuphimisela yaseShayina ye-ginseng.I-Ginseng isitshalo esingapheli se-herbaceous esiyingxenye ye-Araliaceae ginseng.Izitshalo zohlobo lwe-Araliaceae zavela ku-Cenozoic and Tertiary Period, cishe eminyakeni eyizigidi ezingu-60 edlule.Lapho i-Quaternary Ice Age ifika, indawo ababehlala kuyo yancipha kakhulu.I-Ginseng ne-ginseng Ezinye izitshalo kuhlobo nazo ziye zasinda njengezinsalela zasendulo.Lokhu futhi kwanele ukukhombisa ukuthi i-ginseng ingakwazi ukumelana nokuhlolwa kwemvelo nezikhathi, futhi isenomthelela empilweni yomuntu.
Umsebenzi wakudala othi "Iphupho Lezindlu Ezibomvu" ukhuluma nge-"Ginseng Yangrong Pill", okuwumuthi onomsoco u-Lin Daiyu ovame ukuwuphuza.U-Lin Daiyu wayesanda kungena e-Jia Mansion, futhi wonke umuntu wayebonakala entula, ngakho bambuza ukuthi kwenzakalani?Hlobo luni lomuthi?UDaiyu wamamatheka futhi wathi: “Manje ngisawadla amaphilisi e-ginseng Yangrong.”Ukunganeliseki kuyisimiso sokuzivikela esibuthakathaka ngokwemibandela yanamuhla, okubonisa izinzuzo ze-ginseng ekuthuthukiseni ukungatheleleki.Ngaphezu kwalokho, i-“Compendium of Materia Medica” kanye ne-“Dongyibaojian” nazo zirekhoda imiyalelo equkethe i-ginseng.
Ezikhathini zasendulo, i-ginseng yayijatshulelwa ababusi nezikhulu kuphela.Manje iye yaphuma ngokushesha e-Asia, yakha “i-ginseng fever” emhlabeni wonke.Abacwaningi abaningi kanye nezazi sebeqalile ukutadisha i-ginseng nezinye izinto eziphuma kuyo, i-ginseng extract kanye ne-ginsenosides (Ginsenoside) njalonjalo.
AmaSaponins awuhlobo lwe-glycosides futhi akhiwe i-sapogenin noshukela, i-uronic acid noma amanye ama-asidi aphilayo.I-Ginsenosides iwumongo we-ginseng, futhi iyizingxenye eziyinhloko ezisebenza ngokwemithi ze-ginseng, i-panax notoginseng ne-ginseng yaseMelika.Njengamanje, cishe ama-ginsenoside monomers angaba ngu-50 asehlukanisiwe.Ama-ginsenosides akhishwe ngokuqondile ngale ndlela abizwa ngokuthi i-prototype ginsenosides, okuhlanganisa i-Ra, i-Rb1, i-Rb2, i-Rb3, i-Re, i-Rg1, njll. umzimba womuntu.Kodwa-ke, inani lale enzyme emzimbeni lincane kakhulu, ngakho-ke izinga lokusebenzisa umzimba we-prototype ginsenoside liphansi kakhulu.
I-Ginsenoside CK (Inhlanganisela K) iyi-saponin yohlobo lwe-glycol, eyingxenye yama-ginsenosides angavamile.Cishe ayitholakali ku-ginseng yemvelo.Iwumkhiqizo oyinhloko wokucekela phansi kwamanye ama-ginsenosides anokuqukethwe okuphezulu kwe-Rb1 ne-Rg3 emathunjini omuntu.Inomsebenzi ophezulu we-biological kanye nokumuncwa okuphezulu ngumzimba womuntu.Kusukela ngo-1972, u-Yasioka et al.ithole i-ginsenoside CK okokuqala ngqa.Ithiyori "yemikhiqizo yemvelo" iphinde yaqinisekisa umsebenzi webhayoloji we-ginsenoside CK.Ucwaningo oluningi luye lwabonisa ukuthi imisebenzi yayo yokulwa nesimila kanye nokuthuthukisa amasosha omzimba iyona enamandla kakhulu kuwo wonke ama-ginsenosides.
Selokhu i-ginsenoside Rg3 ingene emakethe, impendulo ibingagculisi.Abantu abaningi abazi ukuthi i-ginsenoside Rg3, ebilokhu ithembisa, empeleni iyisakhi esincibilika emanzini namafutha esingakwazi ukumuncwa umzimba womuntu ngokuqondile, futhi izinga lokuyisebenzisa liphansi kakhulu.Kungakhathaliseki ukuthi umzimba udla kangakanani, umphumela wangempela uncane.
Ukuze kunqobe le nkinga, ithimba le-R&D le-Amicogen lithole ngenani elikhulu lokuhlola ukuthi amanye ama-microorganisms emzimbeni womuntu angaguqula ifomu le-PPD le-ginsenosides libe yi-CK ifomu futhi liwamunce futhi liwasebenzise ngokuvula i-β-glucosaminease.Ngemva kweminyaka eyisithupha yocwaningo lwezulu, ithimba lagcina lithuthukise ngempumelelo i-ginsenoside CK ngokuvutshelwa, lafaka isicelo sobuchwepheshe obuhlobene belungelo lobunikazi, kanye namaphepha ahlobene ashicilelwe.Uma kuqhathaniswa nendlela ye-acid-base hydrolysis kanye nendlela yokuguqula i-enzyme, inezinzuzo ezingenakuqhathaniswa mayelana nezindleko zokukhiqiza kanye nokukhiqizwa okukhulu kwezimboni.Phakathi kwazo, okuqukethwe kwe-CK kungafinyelela ku-15%, futhi ukucaciswa okuvamile kungu-3%.Ukukhiqizwa okwenziwe ngokwezifiso kungenziwa ngokuya ngesidingo, futhi okuphezulu kungenziwa ngezifiso i-15%.Ingachazwa njengempumelelo enkulu ocwaningweni lwama-ginsenosides.
Ngenxa yokufika kwe-ginsenoside CK, kunezinye iziqondiso eziningi zocwaningo kanye nemibono yokuvikela impilo yomzimba, futhi izisebenzi ezengeziwe ze-R&D zebhizinisi zizoba nentshisekelo enkulu ekusetshenzisweni kwayo.I-Ginsenoside CK ayigcini nje ngokuba neqhaza elivelele ekusebenzeni kokuzivikela komzimba, kodwa futhi inenani elikhulu lemininingwane yokuhlola ukusekela ukulwa nomdlavuza, ukulwa nesifo sikashukela, i-neuroprotective, ukuthuthukisa inkumbulo kanye nemiphumela yezempilo yesikhumba.Ngokuzayo, imikhiqizo eminingi eholwa yi-ginsenoside CK izongena ezinkulungwaneni zemizi ukuvikela impilo yemindeni yabo.
Isikhathi sokuthumela: Sep-09-2021