LL-DOPA wani nau'i ne na DOPA na halitta da ake amfani da shi wajen maganin cutar Parkinson.L-DOPA shine farkon dopamine da samfurin tyrosine hydroxylase.Target: Dopamine Receptor L-DOPA (L-3,4-dihydroxyphenylalanine) wani sinadari ne da aka yi da kuma amfani da shi a matsayin wani ɓangare na al'adar ilimin halitta na mutane, wasu dabbobi da shuke-shuke.Wasu dabbobi da mutane suna yin ta ta hanyar biosynthesis daga amino acid L-tyrosine.L-DOPA shine mafarin zuwa dopamine neurotransmitters, norepinephrine (noradrenaline), da epinephrine tare da aka sani da catecholamines.L-DOPA za a iya kerarre kuma a cikin sigar sa mai tsabta ana sayar da shi azaman magani na apsychoactive tare da INN levodopa;Sunayen kasuwanci sun haɗa da Sinemet, Parcopa, Atamet, Stalevo, Madopar, Prolopa, da dai sauransu. A matsayin magani ana amfani da shi wajen maganin cututtukan Parkinson da dystonia mai amsa dopamine.L-DOPA ya ketare shingen kwakwalwar jini mai karewa, yayin da dopamine kanta ba zai iya ba.Don haka, ana amfani da L-DOPA don ƙara yawan adadin dopamine a cikin maganin cutar Parkinson da dystonia mai amsa dopamine.George Cotzias da abokan aikinsa sun yi wannan magani a aikace kuma sun tabbatar da su a asibiti, wanda saboda haka suka ci lambar yabo ta Lasker na 1969.Bugu da ƙari, an bincika L-DOPA, tare da haɗin gwiwar DDCI na gefe, a matsayin yiwuwar maganin ciwon ƙafar ƙafa.Koyaya, binciken ya nuna "babu bayyanannen hoto na raguwar alamun cutar".L-DOPA shine madaidaicin ga masu watsawa na neurotransmitters dopamine, norepinephrine (noradrenaline), da epinephrine (adrenaline) waɗanda aka fi sani da catecholamines.
Baya ga matsayinta na halitta da mahimmancin ilimin halitta, ana kuma amfani da L-DOPA a cikin jiyya na asibiti na cutar Parkinson da dystonia mai amsa dopamine.Lokacin amfani da mahallin magunguna, ana amfani da sunan 'levodopa' na INN akai-akai.
Levodopa wani kariyar abinci ne da ke faruwa ta dabi'a da kuma maganin psychoactive da ake samu a wasu nau'ikan abinci da ganyaye (misali, Mucuna pruriens, ko karammiski wake), kuma an haɗe shi daga amino acid L-tyrosine a cikin jikin dabbobi masu shayarwa da kwakwalwa.
Levodopa shine farkon zuwa dopamine neurotransmitters, norepinephrine (noradrenaline), da epinephrine (adrenaline) tare da aka sani da catecholamines.
Baya ga matsayinta na halitta da mahimmancin ilimin halitta, ana kuma amfani da L-DOPA a cikin jiyya na asibiti na cutar Parkinson da dystonia mai amsa dopamine.Lokacin amfani da mahallin magunguna, ana amfani da sunan 'levodopa' na INN akai-akai.
Sunan samfur: L-dopa 98%
Tushen Botanical: Mucuna Pruriens Extract
Sashe: iri (Bushe, 100% na halitta)
Abunda yake aiki: Levodopa (L-dopa)
Hanyar Hakar: Ruwa/ Barasa mai hatsi
Form: kashe-fari foda
Musamman: 5% -99%
Hanyar gwaji: HPLC
Lambar CAS: 59-92-7
Tsarin kwayoyin halitta: C9H11NO4
Nauyin Kwayoyin: 197.19
Solubility: Kyakkyawan solubility a cikin maganin barasa
Matsayin GMO: GMO Kyauta
Shiryawa: a cikin 25kgs fiber ganguna
Adana: Ajiye akwati a buɗe a wuri mai sanyi, busasshiyar wuri, Nisantar haske mai ƙarfi
Rayuwar Shelf: watanni 24 daga ranar samarwa
Aiki:
- 1 .Yana anti-paralysis agitans.Ta hanyar shingen jini-kwakwalwa a cikin nama na kwakwalwa, amma ta hanyar decarboxylation na dopa decarboxylase zuwa dopamine, suna taka rawa.
2. Don mahimmancin rawar jiki da inna na agitans ciwo na rashin maganin rigakafi, kuma a cikin mafi kyawun haske, mai tsanani, ko tsofaffi matalauta.
3. inganta tsoka girma, asarar nauyi.
4. Ƙara yawan kashi da jujjuyawar kashi.
5 .Kayan abinci.
6. Magance parkinsonism da Pakinsonism syndrome, hepatic coma, hepatic coma, cibiyar sadarwa don inganta majiyyaci a farke, inganta bayyanar cututtuka.
7 .Kwantar da barci, inganta garkuwar jiki.
8 .Rashin nauyi.
9 .Ƙara yawan ƙasusuwa da jujjuyawar osteoporosis, ƙara ƙarfin tsoka, haɓaka sha'awar jima'i da aikin jima'i.
Aikace-aikace:
1.Mucuna Pruriens Extract za a iya amfani dashi azaman kari na abinci.
2.Mucuna Pruriens Extract ana amfani dashi azaman sashi a cikin mannen ruwa da rayuwar pelagic ke amfani dashi.
3.Mucuna Pruriens Extract na iya inganta haɓakar tsoka da haɓakar ƙashi da jujjuyawar osteoporosis.
4.Mucuna Pruriens Cire ƙara yawan kashi da jujjuyawar osteoporosis, ƙara ƙarfin tsoka, haɓaka sha'awar jima'i da aikin jima'i.
5.In asibiti amfani, Mucuna Pruriens Extract aka gudanar a cikin kula da Parkinson ta cuta da dopa-responsive dystonia.
6.Domin mahimmancin rawar jiki da inna agitans ciwo na marasa magani immunogenicity, kuma a mafi kyawun haske, mai tsanani, ko tsofaffi matalauta.
7.Treat parkinsonism and Pakinsonism syndrome, hepatic coma, hepatic coma, cibiyar sadarwa don inganta majiyyaci a farke, alamar ingantawa.
8.Mucuna Pruriens Extract ne anti-paralysis agitans.Ta hanyar shingen jini-kwakwalwa cikin nama na kwakwalwa, amma ta hanyar decarboxylation na l-dopa decarboxylase zuwa dopamine, taka rawa.
Ana amfani da 9.Mucuna Pruriens Extract don mahimmancin rawar jiki da inna agitans ciwo na rashin rigakafi na miyagun ƙwayoyi, kuma a mafi kyawun haske, mai tsanani, ko tsofaffi matalauta.
Karin bayani na TRB | ||
Takaddun shaida na tsari | ||
USFDA, CEP, KOSHER HALAL GMP ISO Takaddun shaida | ||
Ingantacciyar inganci | ||
Kusan shekaru 20, fitarwa 40 kasashe da yankuna, fiye da 2000 batches samar da TRB ba su da wani ingancin matsaloli, musamman tsarkakewa tsari, da tsabta da kuma kula da tsabta hadu USP, EP da CP. | ||
Cikakken Tsarin Tsarin inganci | ||
| ▲Tsarin Tabbatar da inganci | √ |
▲ Ikon daftarin aiki | √ | |
▲ Tsarin Tabbatarwa | √ | |
▲ Tsarin Koyarwa | √ | |
v Protocol Audit Protocol | √ | |
▲ Suppler Audit System | √ | |
▲ Tsarin Kayayyakin Kayan Aiki | √ | |
▲ Tsarin Kula da Material | √ | |
▲ Tsarin Kula da Ayyukan Samfura | √ | |
▲ Tsarin Lakabi na Marufi | √ | |
▲ Tsarin Kula da Lafiyar Lantarki | √ | |
▲ Tsarin Tabbatar da Tabbatarwa | √ | |
v Tsarin Mulki | √ | |
Sarrafa Dukan Tushen da Tsari | ||
Ana sarrafa duk albarkatun ƙasa, kayan haɗi da kayan marufi.Dayan kayan da aka fi so da na'urorin haɗi da marufi mai kaya tare da lambar US DMF. |
Yawancin masu samar da albarkatun ƙasa azaman tabbacin wadata.Ƙarfafan Cibiyoyin Haɗin kai don tallafawaCibiyar Botany/Cibiyar Nazarin Kwayoyin Halitta/Academy of Science and Technology/Jami'a