Peb tuaj yeem ua tau yooj yim feem ntau ua tiav peb cov neeg siv khoom hwm nrog peb cov khoom zoo tshaj plaws, tus nqi zoo heev thiab kev txhawb nqa zoo heev vim peb tau muaj cov kws tshaj lij thiab ua haujlwm ntau dua thiab ua haujlwm tau zoo thiab ua tau raws li tus nqi tsim nyog rau Nrov Tsim rau Tuam Tshoj CAS 1094 -61-7 99% NmnNicotinamide Mononucleotide hmoov, Peb zoo siab tos txais cov qhua tuaj noj mov tshiab thiab tsis tu ncua los ntawm txhua qhov chaw ntawm lub neej niaj hnub los tham rau peb rau yav tom ntej kev lag luam koom haum thiab kev sib koom ua tiav!
Peb tuaj yeem ua tau yooj yim feem ntau ua tiav peb cov neeg siv khoom hwm nrog peb cov khoom zoo tshaj plaws, tus nqi zoo heev thiab kev txhawb nqa zoo heev vim peb tau tshaj lij thiab ua haujlwm ntau dua thiab ua tau zoo rau txoj hauv kev zoo rauTuam Tshoj Nmn Hmoov, Cov khoom xyaw Whitening, Cov khoom lag luam thiab cov kev daws teeb meem muaj lub koob npe zoo nrog cov nqi sib tw, kev tsim tshwj xeeb, ua rau kev lag luam tiam sis.Lub tuam txhab insists ntawm lub hauv paus ntsiab lus ntawm yeej-yeej lub tswv yim, tau tsim thoob ntiaj teb kev muag khoom network thiab tom qab-muag kev pab cuam network.
Nicotinamide mononucleotide tej hmoov
Khoom npe:Nicotinamide mononucleotide hmoov
Synonyms: NMN, β-Nicotinamide Mononucleotide, beta-Nicotinamide Mononucleotide
CAS Nr: 1094-61-7
Specifications: 99% min
Molecular Formula: C11H15N2O8P
Molecular LujYog ': 334.221 g/mol
PobNtim: 1kg / hnab, 25kg / nruas
Nicotinamide Mononucleotide yog dab tsi?
Nicotinamide mononucleotide, abbreviated asNMN, muaj cov npe hauv qab no:
β-NMN, BETA-Nicotinamide Mononucleotide;
BETA-NMN;BETA-NICOTINAMIDE MONONUCLEOTIDE;
BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE;
NICOTINAMIDE-1-IUM-1-BETA-D-ribofuranoside 5′-PHOSPHATE;NICOTINAMIDE RIBOTIDE;
NICOTINAMIDE MONONUCLEOTIDE
NMN muaj nyob rau hauv ntau yam kab mob xws li tib neeg thiab yog ib qho tseem ceeb rau kev tswj lub cev ua haujlwm.NMN rov qab siv dua tom qab tau metabolized los ntawm lub cev, thiab vitamin B3 hauv cov zaub mov kuj tseem tuaj yeem tsim NMN.
Ua ntej peb to taub nicotinamide mononucleotide, peb yuav tsum paub tias nws yog dab tsi.Nicotinamide mononucleotide (NMN) yog ib qho tseem ceeb ua ntej ntawm NAD +, thiab NAD + yog ib qho tseem ceeb ntawm kev kho cell hauv tib neeg.Thaum tib neeg nyob hauv cov menyuam mos thiab cov menyuam yaus, lawv txoj kev loj hlob thiab kev loj hlob sai heev, thiab nrog rau cov hnub nyoog nce ntxiv, tib neeg lub cev ua haujlwm yuav maj mam poob.Cov piv txwv yooj yooj yim zoo li qub;koj yuav dig muag los ntawm kev huam yuaj.Cov pob txha tau tsoo, thiab qhov hnyav dua, lawv raug mob hnyav.Nyob rau hauv tus txheej txheem ntawm kev laus ntawm tib neeg lub hlwb, tus nqi ntawm NAD + yuav txo tau ntau npaum li cas piv nrog rau yav dhau los vim metabolism thiab lub cev nws tus kheej.
Nicotinamide mononucleotide yog ib feem tseem ceeb ntawm tib neeg rejuvenation.Cov kws tshawb fawb thoob ntiaj teb tau tshawb pom tias nicotinamide mononucleotide muaj qee yam cuam tshuam rau kev laus.Hauv kev tshawb fawb tob, tus yuam sij rau nicotinamide mononucleotide yog qhov ua ntej ntawm NAD +, uas yuav hloov pauv rau NAD +, ntxiv cov txheej txheem kho cell hauv tib neeg lub hlwb, tiv thaiv cov txheej txheem kev laus, thiab muaj lub sijhawm los rov pib ua haujlwm regrowth hauv lub cell, uas yog lub neej txuas ntxiv ua haujlwm ntawm nicotinamide mononucleotide.
Nicotinamide mononucleotide ib txwm muaj nyob hauv txhua lub cell ntawm peb lub cev thiab yog ib qho tseem ceeb ntawm lub cev kho tus kheej.Nws yog ib qho metabolite rau kev tswj hwm ib txwm NAD + biosynthesis, thiab cov khoom no tuaj yeem tswj lub cev lub cev thaum lub cev ncig, thiab hauv cov kab mob tshwj xeeb.Nws plays lub luag haujlwm tseem ceeb hauv kev ua haujlwm ntawm tes.
Cov khoom noj uas muaj NMN
Tam sim no muaj ntau yam khoom siv NMN ntxiv rau muag.Qee qhov nrov ntawm cov neeg siv kawg, xws li NMN Pure, Ultra NMN, thiab lwm yam ntawm Amazon thiab lwm lub khw hauv online.
Qee cov qauv nrog tsuas yog NNN hauv nws, thiab qee qhov ua ke nrog lwm cov khoom xyaw tiv thaiv kev laus, xws li resveratrol, pterostilbene, pom cov cag extract, thiab lwm yam.
Ob daim ntawv tshuaj ntsiav thiab ntsiav tshuaj muaj, hauv qab no yog qee qhov NMN cov lus qhia tseeb los ntawm qee cov ntawv NMN:
125mg zoo li yog qhov nrov tshaj plaws rau feem ntau cov tshuaj NMN, txawm hais tias qee tus sau 260mg ib capsule ntawm lawv cov ntawv nrog rau qhov loj me ntawm 2 tsiav tshuaj lossis ntsiav tshuaj txhua hnub.Tsis muaj kev pom zoo noj tshuaj tam sim no.
Mechanism ntawm kev ua ntawm nicotinamide mononucleotide
nicotinamide mononucleotide hloov mus rau hauv "nicotinamide adenine dinucleotide (NAD)" cov khoom tseem ceeb rau lub zog metabolism hauv lub cev.Hauv kev sim nas, nws tau lees paub tias nicotinamide mononucleotide tuaj yeem qhib cov noob hu ua acetylase hauv lub cev, yog li ua rau muaj kev cuam tshuam xws li kev ua neej ntev thiab kho ntshav qab zib.NAD yog ib yam khoom uas tuaj yeem tsim los ntawm tib neeg lub cev.Cov kev tshawb fawb tau pom tias cov ntsiab lus NAD hauv lub cev txo qis nrog hnub nyoog.
Kev nce hauv kev mob tshwm sim nrog kev laus tuaj yeem ua rau lub cev tsis muaj peev xwm tsim NMN, uas ua rau txo qis hauv NAD.
NMN yog ib qho khoom ua ntej ntawm coenzyme NAD + tseem ceeb hauv lub cev.Nicotinamide mononucleotide yog lub luag haujlwm tseem ceeb hauv tib neeg lub zog tsim hluav taws xob, thiab nws koom nrog hauv kev sib txuas ntawm intracellular NAD + (nicotinamide adenine dinucleotide, coenzyme rau cell zog hloov).
NMN tau raug lees paub tias yog lub ntiaj teb thawj cov khoom siv ntuj tsim tau lees paub los ntawm kev sim tshawb fawb nruj kom ua tau zoo thim rov qab thiab ncua kev laus thiab ua kom lub neej ntev.
Hauv xyoo 2017, kev tshawb fawb tau pom tias NMN tuaj yeem kho NR thiab NMN ataxia, thiab NR tsis hloov SIRT3 kev ua haujlwm lossis txhim kho lub plawv.
NAD + cov khoom yuav tsis nyob twj ywm - nws tseem yuav tau noj thiab ntxiv, thiab tag nrho NAD + pas dej da dej 2-4 zaug hauv ib hnub.
Lub voj voog no yog los ntawm txoj kev kho, uas cov enzyme Nampt catalyzes NAM rau NMN thiab tom qab ntawd metabolizes rau NAD +.Nampt yog cov kauj ruam txwv ceev hauv cov txheej txheem nuv ntses.
Nicotinamide Mononucleotide VS.Nicotinamide Riboside
Niaj hnub no, lub ntiaj teb no muaj ntau yam kev tshawb fawb nrog NR, thiab kev sim ntawm tib neeg lub cev ua rau cov txiaj ntsig ntawm NR ntawm cov ntaub ntawv theoretical zoo dua NMN.Txawm li cas los xij, cov kev tshawb fawb tau pom tias NR pib ua haujlwm hauv tib neeg lub cev thiab tseem yuav tsum tau ntsib ib ntus.Qhov tseem ceeb yog tias ob qho tib si NR thiab NMN yog qhov ua ntej ntawm NAD +, thaum Nicotinamide Riboside (NR) yog qhov ua ntej ntawm NMN thiab NAD +, yog li NR hloov pauv.Nws yuav siv sij hawm ib pliag ua ntej NAD +.Piv nrog rau cov nyhuv tam sim ntawm NMN, 15 feeb ntawm NR yog qhov sib txawv loj.
Nws tuaj yeem pom los ntawm daim duab kos duab saum toj no uas NAMPT yog qhov tseem ceeb txwv tsis pub muaj NMN tiam.Raws li lub hnub nyoog nce, tsis yog tib neeg lub cev tsis xav kom yau, tab sis cov enzyme kev ua ntawm NAMPT txo qis thaum lub zog thiab cov as-ham tau muab.Raws li lub voj voog ntawm NAM raug txo, cov Tshuag ntawm NAD + yog ib txwm txo.
NR tuaj yeem hloov mus rau NMN lossis rau NAM, nyob ntawm lub luag haujlwm ntawm Nrk1 enzyme los txiav txim siab yam khoom ntawm tib yam zoo NR yuav tsim ntau dua.Yog tias nws hloov mus rau NAM, nws kuj raug txwv los ntawm NAMPT enzyme.Piv nrog rau qhov ncaj qha kev txiav txim ntawm NMN los tsim NAD +, cov nyhuv ntawm qhov sib npaug ntawm NR yog pom tseeb tsis muaj zog ntau.
Vim li cas ho tsis noj NAD +?
NAD + tsis tuaj yeem coj ncaj qha mus rau hauv lub hlwb los ntawm kev tswj hwm qhov ncauj vim nws qhov hnyav molecular ntau dhau.Qhov ntxiv ntawm NAD + tsuas yog ua tiav los ntawm kev noj cov khoom hnyav me me NAD + ua ntej.
Txawm li cas los xij, NMN tuaj yeem ua rau ntau yam khoom, uas tuaj yeem yog cov tshuaj ntsiav, ntsiav tshuaj, lossis txawm tias granules vim nws qhov dej soluble.Solubility ntawm NMN hauv dej yog 35mg / ml.
Hauv qhov kev nkag siab no, NMN zoo dua NAD +, thiab ncaj qha ntau dua li nicotinamide riboside.
Nicotinamide Mononucleotide cov txiaj ntsig
Cov teebmeem tseem ceeb ntawm NMN yog raws li hauv qab no:
- tiv thaiv oxidation
- Relieve physiological poob
- kho DNA
- Txhawb cov teebmeem neuroprotective
- Txhim kho lub plawv ua haujlwm thiab tiv thaiv lub plawv
- Txhim kho cov xwm txheej ntawm Alzheimer's cov neeg mob
Qhov tshwj xeeb tshaj plaws ntawm NMN yog tias nws tuaj yeem thim rov qab kev laus thiab ua kom lub neej ntev.
Nicotinamide Mononucleotide phiv
Txij li NMN tam sim no tsuas yog ua cov kev sim tsiaj xwb, kev sim loj ntawm tib neeg tseem tsis tau pib, yog li cov kev mob tshwm sim uas tuaj yeem txiav txim siab tseem tsis meej.Txawm li cas los xij, raws li kev ua haujlwm ntawm NMN, nws tuaj yeem suav tau tias cov neeg mob qog noj ntshav yuav tsum tsis txhob noj ntau li ntau tau.Vim tias NMN hloov pauv txhawb kev tsim NAD +, thaum cov qog nqaij hlav qog noj ntshav hloov mus rau kev ua haujlwm ntawm lub cev qeeb, qhov nce hauv cov metabolism yuav ua rau muaj kev sib kis ntawm qee cov qog nqaij hlav cancer.
Thaum siv cov tshuaj nicotinamide nucleoside xws li NMN, kev tawm dag zog yuav cuam tshuam.Hauv cov nas, nas txhaj nrog NAD + cov tshuaj ntxiv tau pom qhov ua tau zoo dua li lawv pawg tswj hwm.
