PRL-8-53, qhov tshiab tshaj plaws nootropic, tseem paub los ntawm nws cov tshuaj npe Methyl 3-[2-[benzyl (methyl)amino]ethyl] benzoate yog ib qho hluavtaws nootropic ntxiv.Nws tau tsim nyob rau xyoo 1970's los ntawm Dr. Nikolaus Hansl ntawm Creighton University hauv Nebraska.Nws tau muaj qee qhov kev tshawb fawb tib neeg uas pom cov lus teb zoo hauv kev paub txog kev ua haujlwm.Ib txoj kev tshawb fawb pom tau tias qhov sib xyaw ua ke tuaj yeem pab khaws cov kev nco ploj (hypermnesia).
Khoom npe: PRL-8-53
Lwm Lub Npe: Methyl 3-(2-(benzylmethylamino)ethyl) benzoate hydrochloride
3-(2-benzylmethylaminoethyl) benzoic acid methyl ester hydrochloride
3-(2-(Methyl (phenylmethyl)amino)ethyl) benzoic acid methyl ester hydrochloride
CAS Nr .: 51352-87-5
Kev Ntsuas: 98%
Qhov tsos: Dawb hmoov
PRL-8-53 Ua haujlwm li cas?
PRL-8-53 yog muab los ntawm kev sib xyaw ntawm benzoic acid thiab phenylmethylamine.Cov qauv tshuaj tsim los ntawm kev sib xyaw ntawm ob lub tebchaw no ua rau muaj kev cuam tshuam nrog cholinergic receptors, uas koom nrog hauv kev hloov pauv kev nco thiab kev kawm hauv lub hlwb.PRL-8-53 kuj tseem paub tias muaj zog (nce cov nyhuv ntawm) dopamine thiab ib nrab inhibits serotonin receptors.Dr. Nikolaus Hansl ntseeg hais tias qhov txiaj ntsig zoo no yuav ua rau muaj kev hloov pauv ntawm qhov sib npaug hauv CNS neurotransmitter systems thiab ua rau kev txawj ntse ua haujlwm zoo dua.
Tsuas muaj ib qho kev tshawb fawb tib neeg tau ua ntej los ntsuas qhov cuam tshuam ntawm cov tshuaj thiab nws pom tias muaj kev txhim kho hauv kev nco qab, lub sijhawm pom kev pom thiab kev tswj lub cev muaj zog, tshwj xeeb tshaj yog cov neeg muaj hnub nyoog 30 xyoo. thiab kev txawj ntse poob qis, yog li ntawd, kev nco thiab kev paub txog kev pab txhawb nqa yuav ua haujlwm zoo dua rau lawv.
RPL-8-53 Muaj nuj nqi:
Txhim khu kev puas hlwb
Boost nco thiab leaning peev xwm
Txhim kho lub hlwb lub zog los daws cov teeb meem thiab tiv thaiv nws los ntawm kev raug mob los yog lub cev
Txhim kho qib kev txhawb siab
Txhim khu kev tswj ntawm cortical / subcortical hlwb mechanism
Txhim kho qhov kev nkag siab zoo
Dosage thiab phiv
Cov ntaub ntawv patent muaj rau PRL 8-53 qhia txog qhov ntau ntawm 0.01-4mg / kg ntawm lub cev hnyav.Txawm li cas los xij, vim tias muaj ntau yam loj, qhov zoo tshaj plaws yog 0.05-1.2 mg / kg.Qhov no txhais tau hais tias 3.4mg-81.6mg rau 150 phaus tus neeg thiab 4.55mg-109mg rau ib tus neeg 200 phaus.Hauv kev sim tib neeg, tsis muaj kev mob tshwm sim raug kaw;Txawm li cas los xij, txo cov kev ua haujlwm ntawm lub cev muaj zog tau sau tseg hauv cov nas thiab nas thaum muab cov koob tshuaj loj ntawm PRL 8-53.
