10-Deacetylbaccatin III (10-DAB）)

10-Deacetylbaccatin III (X-DAB） imago Featured)
  • 10-Deacetylbaccatin III (10-DAB）)

Brevis descriptio:

10-Deacetylbaccatin III (C29H36O10) est diterpenoideus bioactive naturaliter ex acus et cortice extractusTaxusspecies (arbores taxi). Sicut clavis praecursor in semi-synthesi paclitaxel, docetaxel, et aliis agentibus chemotherapeuticis taxaneis substructio, 10-DAB late in usu est in pharmaceutica R&D et oncologia medicamentorum productionis.

10-Deacetylbaccatin III, etiam ut dicitur 10-DAB vel 10-DAB III, est compositio organica propinqua naturalis solitaria ab acus arida et ramulis taxi Europaei arboris (Taxus baccata).10-Deacetylbaccatin III praecursor anti-cancri medicamento docetaxel (Taxotere). pacitaxel (taxol); cabazitaxel. 10-10-deacetylbaccatin III inventum est selective inhibere incrementum L. DONOVANI amastigotis intracellulares intra J774 macrophages murinas in vitro ad concentrationes nanomolares cum IC(50) valoris 70 nm.


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    Product Detail

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    Nomen chemicum: 10-Deacetylbaccatin III

    CAS Number:

    32981-86-5
    Synonyma:

    10-Desacetylbaccatin III; 10β-Deacetylbaccatin III; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dod ecahydro-4,6,9,11-tetrahydroxum-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodecum[3,4]benz[1,2-b] bovis 5-unum; 7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b] oxet-5-una, 12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy13-; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-; (Docetaxel USP Impuritas);10-Deacetylbaccatin III; 10-Deacetyl baccatin; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-1,2a,3,4,4a,6,9,10,11,12,12a; 12b-Dodecahydro-4a,6,9,11,12,12b-hexahydroxia-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b] bovis 5-una 12b-acetata, 12 benzoata (USP);
    Forma hypothetica: C29H36O10
    Aspectus: Solidus albus
    Mol. Pondus: 544.6
    Repono: 2-8°C Refrigerator

    Subtitle: Plant-Derivata API Intermedia, CAS32981-86-5| GMP Certified, COA dummodo

    Quid est 10-Deacetylbaccatin III (10-DAB)?

    10-Deacetylbaccatin III (C29H36O10) est diterpenoideus bioactive naturaliter ex acus et cortice extractusTaxusspecies (arbores taxi). Sicut clavis praecursor in semi-synthesi paclitaxel, docetaxel, et aliis agentibus chemotherapeuticis taxaneis substructio, 10-DAB late in usu est in pharmaceutica R&D et oncologia medicamentorum productionis.

    Key Specifications & Features

    • Puritas: ≥98% (HPLC-UV convalescit, COA praesto)
    • Aspectus: Alba ad extemporalitatem album crystallinum pulveris
    • Solubilitas: Solubilis in methanolo, ethanol, DMSO; leviter solutum in aqua
    • Repono: Stabilis ad -20°C in airtight vasis, tutis a luce
    • Plant Source: Sustentabiliter colligiturTaxus wallichiana(Himalayan taxus)

    Applications of 10-DAB

    1. Anticancer medicamentum synthesis
      • Medium criticum pro productione semi-synthetica paclitaxel (Taxol®) et docetaxel (Taxotere®).
      • Adhibetur in R&D pro novis derivationibus taxaneis carcinomata medicamentorum repugnantium.
    2. Investigatio diam
      • Studium polymerizationis tubulinum mechanismi et apoptosis inductionis.
      • Relatio vexillum pro analytica chemiae et qualitatis potestate.
    3. Natural Product Extraction
      • Summus processus cedat extractionis obsequentem cum principiis chemiae viridis.

    Cur Source 10-DAB a Nobis?

    Certified Quality:

    • Batch-certum certificatorium Analyseos (COA) cum HPLC, MS, NMR datae.
    • Obsequium cum USP, EP, et ICH Q7 GMP lineamenta.

    Sustainable Sourcing:

    • Electa ex plantis Taxi ethice colligitur (CITES Appendix II obsecunda).

    ✅ Global Logistics:

    • Seamless frigoris catenae naves in USA, EU et APAC regiones.
    • Mos packaging (1g ad 1kg, phialas vitreas electri cum desiccant).

    Technical Support & Documentation

    • Free MSDS (Material Salutis Data Sheet) et stabilitas data postulantibus.
    • Custom synthesis and size pricing available for OEM socii.
    • Subsidia dedicaverunt regulatory pro IND/NDA submissionibus.

    Salus & Obsequium

    • CAS Number: 32981-86-5
    • Periculosi Codices: Palpate cum PPE (chirothecae, goggles) - non-ancipites ad usum professionalem.
    • Regulatory Status: SPATIUM relatus; DMF praesto pro clientibus pharmaceuticis.

    FAQs pro X-DAB

    Q: Num 10-DAB directe in studiis culturae cellae adhiberi potest?
    A: No. Postulat modificationem chemica (eg, additionis lateralis) ut taxanes bioactivae fiant.

    Q: Quid primum tempus 500g ordines?
    A: Standard production time: 2-3 septimanas. Express shipping available.

    Q: Praestare taxane synthesin protocolla?
    A: Ita! Technical whitepapers available pro clientibus idoneis.

    Descriptio:
    Source 98% HPLC-gradus 10-Deacetylbaccatin III (CAS 32981-86-5) - GMP certificatum Taxum extractum pro synthesi paclitaxel. Moles ordines, COA/MSDS, et subsidia moderantia inclusa.

    1. Keywords:
      • Primaria: "Deacetylbaccatin III annonae", "puritatis summa 10-DAB", "Paclitaxel praecursor".
      • Long-caudam: "CAS 32981-86-5 pretium", "Taxum extractum ad investigationem cancri", "GMP 10-DAB"
    2. Keywords:
      • "Taxane medium", "paclitaxel semi-syntheticum", "C29H36O10", "arboris taxus composita".
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