Ko te Beta-nicotinamide Mononucleotide (NMN), he hua o te tauhohenga NAMPT me te matua NAD + takawaenga, ka whakapai ake i te manawanui o te huka ma te whakaora i nga taumata NAD + i roto i nga kiore T2D-a-HFD.Ko te NMN te whakanui ake i te taikaha o te insulin ate me te whakahoki ano i te whakaaturanga ira e pa ana ki te ahotea oxidative, te urupare mumura, me te manawataki circadian, tetahi waahanga ma te whakahohe SIRT1.Ka whakamahia te NMN mo te ako i nga kaupapa here i roto i nga aptamers RNA me nga tukanga whakahohe ribozyme e uru ana ki te β-nicotinamide mononucleotide (Beta-NMN) -whakahohe nga kongakonga RNA.
Ko Nicotinamide mononucleotide ("NMN" me "β-NMN") he nucleotide i puta mai i te ribose me te nicotinamide.Ko te Niacinamide (nicotinamide,) he ahua o te huaora B3 (niacin.) Hei tohu koiora o te NAD +, ka whai hua pea ki te aukati i te pellagra.
Ko te ahua o te niacin, ka kitea i roto i nga momo puna kai: Pīnati, Harore (portobello, tunua), Avocados, Pea Green (hou), me etahi momo ika me nga kai kararehe.
I roto i nga rangahau [mo nga kiore], kua whakaatu a NMN ki te whakahuri i te mate o te taikaha e pa ana ki te pakeke ma te whakaheke i te ahotea oxidative.
Ingoa: Beta-Nicotinamide Mononucleotide
CAS ＃: 1094-61-7
Ingoa Hua: Beta-Nicotinamide Mononucleotide；NMN
Ētahi atu ingoa:β-D-NMN;BETA-NMN;beta-D-NMN;NMN zwitterion;Nicotinamide Ribotide;Nicotinamide nucleotide;Nicotimide mononucleotide;Nicotinamide mononuclotide
CAS:1094-61-7
tātai rāpoi: C11H15N2O8P
Taumaha rāpoi: 334.22
Maama:98%
Te Paemahana Rokiroki: 2-8°C
Te ahua: Te paura ma
Whakamahia: anti-hoholo
Taumahi:
1.Nicotinamide mononucleotide i roto i ngā pūtau tangata whai wāhi nui i roto i te hanga pūngao, whai wāhi i roto i te NAD intracellular (nicotinamide adenine dinucleotide, pūngao pūngao faafariuraa coenzyme nui) synthesis, whakamahia i roto i te anti-hoholo, hinga huka toto me ētahi atu hua tiaki hauora.
2. Ko te Nicotinamide Mononucleotide he huaora wairewa-wai, Ko te hua he paura tioata ma, he kakara, he tata kore ranei, he kawa te reka, he waatea noa i roto i te wai, i te waiwaro ranei, ka memeha ki te glycerin.
3.Ko te Nicotinamide Mononucleotide he ngawari ki te whakauru-waha, ka taea te tohatoha whanui ki roto i te tinana, ka tere te peia o nga metabolites me te tauira tauira mai i te mimi.Ko te Nicotinamide tetahi waahanga o te coenzyme I me te coenzyme II, ka whai waahi ki te tuku hauwai i roto i nga mekameka whakangao koiora koiora, ka taea te whakatairanga i nga tikanga whakangao koiora me te whakangao o te kiko, te pupuri i te kiko noa (ina koa te kiri, te kopa kūnatu me te punaha nerve) he mahi nui te tapatahi. .
I tua atu, ko te nicotinamide he aukati me te maimoatanga o te paraka ngakau, te mahi node sinus me nga arrhythmias whakamatautau anti-tere, ka taea e te nicotinamide te whakapai ake i te tere o te ngakau me te paraka atrioventricular na te verapamil.
