Lebitso la sehlahisoa:Phofo ea Gamma-glutamylcysteine
Mantsoe a tšoanang: gamma-L-Glutamyl-L-cysteine, γ -L-Glutamyl-L-cysteine, γ-glutamylcysteine, GGC, (2S) -2-Amino-5-{[(1R) -1-carboxy-2- sulfanylethyl]amino}-5-oxopentanoic acid, cysteine, Continual-G
Foromo ea Molek'hule: C8H14N2O5S
Boima ba 'mele: 250.27
Nomoro ea CAS: 686-58-8
Ponahalo/Mmala: Phofo e tšoeu ea kristale
Solubility: Ho qhibiliha ka metsing
Melemo: selelekela sa glutathione
Gamma-glutamylcysteineke dipeptide mme ke selelekela sa kapele ho tripeptideglutathione (GSH).Gamma glutamylcysteine e na le mabitso a mang a mangata, a kang γ -L-Glutamyl-L-cysteine, γ-glutamylcysteine, kapa GGC ka bokhutšoanyane.
Gamma Glutamylcysteine ke phofo e tšoeu ea kristale e nang le foromo ea molek'hule C8H14N2O5S 'me e na le boima ba molek'hule ea 250.27.Nomoro ea CAS ea komporo ena ke 686-58-8.
Gamma-glutamylcysteine VS Glutathione
Molek'hule ea Gamma glutamylcysteine ke selelekela sa glutathione.E ka kena liseleng 'me ea fetoha e ngata ea antioxidant ena e matla ha e le ka har'a enzyme ea bobeli ea motsoako e bitsoang glutathione synthetase.Sena se ka fana ka phomolo khatellong ea oxidative haeba se thusa lisele tse nang le GCL e holofetseng hore li hlaphoheloe 'me li boele li fumane tšebetso e tloaelehileng ntoeng e sa feleng ea bophelo khahlanong le li-radicals tsa mahala tse senyang lisele tsohle tse phetseng hantle ha nako e ntse e ea!
Khatello ea intracellular ea gamma-glutamylcysteine (GGC) hangata e tlase hobane e kopana le glycine ho theha glutathione.Ts'ebetso ena e etsahala ka potlako, kaha GGC e na le halofo ea bophelo ba metsotso ea 20 ha e le cytoplasm.
Leha ho le joalo, tlatsetso ea Oral le e kentsoeng ka glutathione ha e khone ho eketsa glutathione ea cellular ho batho.Glutathione e potolohang e ke ke ea kena liseleng e ntse e tiile 'me e tlameha ho qala ka ho aroloa ka likarolo tsa eona tse tharo tsa amino acid, glutamate, cysteine, le glycine.Phapang ena e kholo e bolela hore ho na le "concentration gradient" e ke keng ea hlōloa lipakeng tsa tikoloho ea extracellular le intracellular, e thibelang ho kenngoa ha lisele tse ling.Gamma-glutamylcysteine e ka 'na ea e-ba karolo ea bohlokoa ho tsamaiseng GSH ho pholletsa le likokoana-hloko tse ngata.
Gamma-glutamylcysteine VS NAC (N-acetylcysteine)
Gamma-Glutamylcysteine ke motsoako o fanang ka lisele tsa GGC, tseo li li hlokang ho hlahisa Glutathione.Lisebelisoa tse ling tse kang NAC kapa glutathione li ke ke tsa etsa sena ho hang.
Gamma-glutamylcysteine Mokhoa oa ts'ebetso
GGC e sebetsa joang?Mochine o bonolo: o khona ho eketsa maemo a glutathione kapele.Glutathione ke amino acid ea bohlokoa e etsang mesebetsi e mengata 'meleng le ho sireletsa khahlanong le chefo.Glutathione e nka karolo e le cofactor bakeng sa e 'ngoe ea li-enzyme tse tharo tse fetolang leukotrienes ho thusa ho fokotsa matšoao a asthma, e thusa ho lokolla lintho tse chefo liseleng e le hore li ka ntšoa ke bile ka har'a mantle kapa moroto, ho lokisa tšenyo ea DNA e bakiloeng ke li-radicals tsa mahala tse nang le thepa ea eona ea antioxidant, e tlatsa glutamine ka mor'a ho ikoetlisa ho ntlafatsa ts'ebetso ea 'mele ea ho itšireletsa mafung ka tlhahiso ea li-antibodies tse kang IgA (immunoglobulin A) e re thusang ho re sireletsa khahlanong le tšoaetso ea phefumoloho nakong ea serame ha re le bonolo haholo ho eona-tsena tsohle ha re ntse re bapala karolo ea bohlokoa libakeng tse ling tse kang ho laola metabolism!
Mokhoa oa tlhahiso ea Gamma-glutamylcysteine
Tlhahiso ea likokoana-hloko ka ho belisoa ho theosa le lilemo 'me ha ho le e' ngoe e atlehileng ho rekisoa.Mokhoa oa biocatalytic oa Gamma-glutamylcysteine o ile oa rekisoa ka katleho fekthering ea Cima Science.GGC e se e fumaneha joalo ka tlatsetso naheng ea US tlasa lebitso la khoebo la Glyteine le Continual-G.
Melemo ea Gamma-glutamylcysteine
Gamma-glutamylcysteine e netefalitsoe hore e matlafatsa maemo a cellular glutathione nakong ea metsotso e 90.Glutathione, ts'ireletso ea mantlha ea 'mele khahlano le li-radicals tsa mahala, e tsebahala ka ho thusa ho fokotsa khatello ea oxidative ho tsoa ho li-radicals tsa mahala le ho ts'ehetsa mesebetsi e fapaneng ea' mele ho kenyelletsa le detoxification.
- Tšehetsa sebete, boko le bophelo bo botle ba 'mele
- E matla ea antioxidant le detoxifier
Glutathione e bohlokoa ho nyenyefatsa 'mele oa hau mme e ts'ehetsa ts'ebetso ea sebete, liphio, pampitšana ea GI le mala.Glutathione e bapala karolo ea bohlokoa ho boloka tsamaiso ea 'mele e sebetsa hantle ka ho thusa litseleng tsa detoxification ho kenyeletsa le tse fumanoang ka har'a mali hammoho le litho tse kholo tse kang liphio, pampitšana ea GI kapa mala. - Khothaletsa matla, ho tsepamisa maikutlo, le ho tsepamisa maikutlo
- Phepo ea lipapali
Maemo a glutathione a ka u thusa ho sebetsa hantle ka ho fetisisa, ho phela hantle 'me u fole habonolo.Etsa bonnete ba hore o eketsa glutathione ka lijo kapa tlatsetso e le hore lisele tsa 'mele li sebetse hantle le ho sebetsa ka katleho e le hore li khone ho fokotsa nako ea ho hlaphoheloa ka mor'a ho ikoetlisa.
Litla-morao tsa Gamma-glutamylcysteine
Gamma-glutamylcysteine e ncha 'marakeng oa tlatsetso,' me ha ho na litlamorao tse mpe tse tlalehiloeng hajoale.Ka kakaretso e lokela ho bolokeha ho nkoa ho latela keletso ea ngaka ea hau.
Tekanyetso ea Gamma-glutamylcysteine
Tlhahlobo ea polokeho ea letsoai la sodium ea GGC ho likhoto e bonts'itse hore GGC e tsamaisoang ka molomo (gavage) e ne e se chefo e matla ho tekanyo e le 'ngoe ea 2000 mg / kg, e sa bonts'ang litlamorao tse mpe kamora ho nooa khafetsa letsatsi le letsatsi ho feta matsatsi a 90.
