10-Deacetylbaccatin III (10-DAB)

Tlhaloso e Khutšoanyane:

10-Deacetylbaccatin III (C29H36O10) ke bioactive diterpenoid ka tlhaho e ntšitsoeng linaleng le makhapetla aLekhethomefuta (lifate tsa yew). E le selelekela sa mantlha ho semi-synthesis ea paclitaxel, docetaxel, le liakhente tse ling tse thehiloeng ho taxane tsa chemotherapeutic, 10-DAB e sebelisoa haholo tlhahisong ea meriana ea R&D le tlhahiso ea lithethefatsi tsa oncology.

10-Deacetylbaccatin III, e tsejoang hape e le 10-DAB kapa 10-DAB III, ke metsoako ea tlhaho e amanang haufi-ufi e arohaneng le linale tse omisitsoeng le makala a manyenyane a sefate sa yew sa Europe (Taxus baccata) .10-Deacetylbaccatin III ke selelekela sa lithethefatsi tse khahlanong le kankere docetaxel (Taxotere). pacitaxel (taxol); cabazitaxel. 10-10-deacetylbaccatin III e fumanoe e thibela ka mokhoa o ikhethileng ho hōla ha L. DONOVANI intracellular amastigotes ka har'a J774 murine macrophages in vitro ka nanomolar concentrations le IC (50) bohlokoa ba 70 nM.

FOB Theko:US 5 - 2000 / KG

Bongata ba Odara:1KG

Matla a Phepelo:10000 KG/Kgwedi

Boema-kepe:Shanghai / Beijing

Melao ea Tefo:L/C,D/A,D/P,T/T,O/A

Melao ea ho Romela:Ka leoatle/Ka Moea/Ka Courier

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Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Lebitso la lik'hemik'hale:	10-Deacetylbaccatin III
Nomoro ea CAS:	32981-86-5
Mantsoe a tšoanang:	10-Desacetylbaccatin III; 10β-Deacetylbaccatin III; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dod ecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one; 7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 12b-(acetyloxy) -12-(benzoyloxy) -1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-; (Docetaxel USP Ho se hloeke);10-Deacetylbaccatin III; 10-Deacetyl baccatin; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS) -1,2a,3,4,4a,6,9,10,11,12,12a, 12b-Dodecahydro-4,6,9,11,12,12b-hexahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one 12b-acetate, 12-acetate (USPbenzo);
Mofuta oa molek'hule:	C29H36O10
Ponahalo:	White Tiileng
Mol. Boima ba 'mele:	544.6
Polokelo:	2-8 ° C Sehatsetsi

Subtitle: Plant-Derived API Intermediate, CAS32981-86-5| GMP e netefalitsoe, COA e Fanoe

10-Deacetylbaccatin III ke eng?10-DAB)?

Litlhaloso tsa Bohlokoa le Likarolo

Bohloeki: ≥98% (HPLC-UV e netefalitsoe, COA e teng)
Ponahalo: Phofo ea kristale e tšoeu ho isa bosoeu
Solubility: Ho qhibiliha ka methanol, ethanol, DMSO; e qhibilihang hanyane ka metsing
Polokelo: E tsitsitse ho -20 ° C ka har'a lijana tse sa keneng moea, tse sirelelitsoeng leseli
Mohloli oa Semela: Kotuloa ka mokhoa o tsitsitsengTaxus wallichiana(Himalayan yew)

Lisebelisoa tsa 10-DAB

Anticancer Drug Synthesis
- Bohareng ba bohlokoa bakeng sa tlhahiso ea semi-synthetic ea paclitaxel (Taxol®) le docetaxel (Taxotere®).
- E sebelisoa ho R&D bakeng sa lintho tse nkiloeng tsa taxane tse shebaneng le mofetše o hananang le lithethefatsi.
Patlisiso ea Lik'hemik'hale
- Boithuto ba mekhoa ea polymerization ea tubulin le apoptosis induction.
- Tekanyetso ea litšupiso bakeng sa khemistri ea tlhahlobo le taolo ea boleng.
Tlhaho ea Sehlahisoa sa Tlhaho
- Ts'ebetso ea ho ntša lihlahisoa tse phahameng e lumellana le melao-motheo ea k'hemistri e tala.

Ke Hobane'ng ha U ka Fumana 10-DAB ho Rona?

✅ Boleng bo netefalitsoeng:

Setifikeiti sa Tlhahlobo se Ikhethileng ka sehlopha (COA) se nang le lintlha tsa HPLC, MS, NMR.
E tsamaellana le litataiso tsa USP, EP, le ICH Q7 GMP.

✅ Tlhahiso e tsitsitseng:

E kotuloa ka mekhoa e metle masimong a lenngoeng a Taxus (CITES Appendix II e lumellana).

✅ Global Logistics:

Ho romelloa ka likepe tse batang ho ea libakeng tsa USA, EU le APAC.
Ho paka ka mokhoa o ikhethileng (1g ho isa ho 1kg, linkho tsa khalase tsa amber tse nang le desiccant).

Tšehetso ea Theknoloji & Litokomane

MSDS ea Mahala (Material Safety Data Sheet) le data ea botsitso ha e kopa.
Litheko tsa tloaelo le litheko tse ngata li fumaneha bakeng sa balekane ba OEM.
Ts'ehetso e inehetseng ea taolo bakeng sa tlhahiso ea IND/NDA.

Polokeho le Boikamahanyo

Nomoro ea CAS: 32981-86-5
Likhoutu tsa Kotsi: Tšoara ka PPE (liatlana, likhalase) - e seng kotsi bakeng sa ts'ebeliso ea litsebi.
Boemo ba Taolo: REACH e ngolisitsoe; DMF e fumaneha bakeng sa bareki ba meriana.

Lipotso tsa 10-DAB

P: Na 10-DAB e ka sebelisoa ka kotloloho lithutong tsa setso sa lisele?
A: Che. E hloka phetoho ea lik'hemik'hale (mohlala, tlatsetso ea mahlakoreng) hore e be li-bioactive taxanes.

P: Nako ea ho etella pele ea 500g ke efe?
A: Nako e tloaelehileng ea tlhahiso: libeke tse 2-3. Express shipping e teng.

P: Na o fana ka liprothokholo tsa taxane synthesis?
A: Ho joalo! Lipampiri tse tšoeu tsa tekheniki li fumaneha bakeng sa bareki ba tšoanelehang.

Tlhaloso:
Mohloli oa 98% HPLC-grade 10-Deacetylbaccatin III (CAS 32981-86-5) - GMP-certified Taxus extract for paclitaxel synthesis. Litaelo tse ngata, COA/MSDS, le tšehetso ea taolo e kenyelelitsoe.

Mantsoe a sehlooho:
- Ea mantlha: "10-Deacetylbaccatin III mofani oa thepa", "High purity 10-DAB", "Paclitaxel precursor"
- Mohatla o molelele: "CAS 32981-86-5 theko", "Taxus extract bakeng sa lipatlisiso tsa kankere", "GMP 10-DAB"
Mantsoe a sehlooho:
- “Taxane intermediate”, “semi-synthetic paclitaxel”, “C29H36O10″, “yew tree compound”