PRL-8-53, nootropic e ncha ka ho fetisisa, e tsejoang hape ka lebitso la eona la lik'hemik'hale Methyl 3- [2- [benzyl (methyl) amino] ethyl] benzoate ke motsoako oa nootropic oa maiketsetso.E thehiloe lilemong tsa bo-1970 ke Dr. Nikolaus Hansl Univesithing ea Creighton e Nebraska.E bile le lithuto tse ling tsa batho tse bontšitseng likarabo tse ntle ts'ebetsong ea kelello.Phuputso e 'ngoe e bontšitse hore motsoako o ka thusa ho khutlisa mehopolo e lahlehileng (hypermnesia).
Lebitso la Sehlahisoa:PRL-8-53
Lebitso le Leng: Methyl 3-(2-(benzylmethylamino)ethyl)benzoate hydrochloride
3-(2-benzylmethylaminoethyl) benzoic acid methyl ester hydrochloride
3-(2-(Methyl(phenylmethyl)amino)ethyl)benzoic acid methyl ester hydrochloride
Nomoro ea CAS : 51352-87-5
Tekanyo: 98%
Ponahalo: Phofo e tšoeu
PRL-8-53 e sebetsa joang?
PRL-8-53 e tsoa ho motsoako oa benzoic acid le phenylmethylamine.Sebopeho sa lik'hemik'hale se entsoeng ka motsoako oa metsoako ena e 'meli se fella ka motsoako o ka sebelisanang le li-receptor tsa cholinergic, tse amehang ho fetola mohopolo le mekhoa ea ho ithuta ka hare ho boko.PRL-8-53 e boetse e tsejoa ka ho matlafatsa (ho eketsa phello ea) dopamine le ho thibela li-receptor tsa serotonin ka mokhoa o itseng.Dr. Nikolaus Hansl o ne a lumela hore boemo bona ba phello bo ka 'na ba lebisa phetohong ea ho leka-lekana ho tsamaiso ea methapo ea methapo ea CNS 'me ea lebisa ho ntlafatseng ts'ebetso ea kelello.
Ho bile le thuto e le 'ngoe feela ea kliniki ea batho e entsoeng esale pele ho hlahloba liphello tsa lithethefatsi' me e bontšitse ntlafatso ea mohopolo oa mantsoe, nako ea pono ea maikutlo le taolo ea motlakase, haholo-holo ho ba fetang lilemo tsa 30. Batho ba hōlileng ba atisa ho ba le mohopolo. le ho fokotseha ha kelello, ka hona, li-supplement tsa ho hopola le ho matlafatsa kelello li atisa ho sebetsa hamolemo ho tsona.
RPL-8-53 Mesebetsi:
Ntlafatsa bohlale ba kelello
Matlafatsa mohopolo le bokhoni ba ho itšetleha
Ntlafatsa matla a boko ho rarolla mathata le ho a sireletsa ho tsoa kotsi efe kapa efe ea lik'hemik'hale kapa 'meleng
Ntlafatsa boemo ba tšusumetso
Ntlafatsa taolo ea mochini oa boko ba cortical/subcortical
Ntlafatsa temoho ea kutlo
Tekanyo le litla-morao
Lintlha tsa patent tse fumanehang bakeng sa PRL 8-53 li fana ka maikutlo a mefuta e fapaneng ea 0.01-4mg/kg ea boima ba 'mele.Leha ho le joalo, kaha ke mefuta e mengata haholo, tekanyo e loketseng ke 0.05-1.2 mg / kg.Sena se fetolela ho 3.4mg-81.6mg bakeng sa motho oa lik'hilograma tse 150 le 4.55mg-109mg bakeng sa motho oa lik'hilograma tse 200.Tekong ea motho, ha ho litla-morao tse tlalehiloeng;leha ho le joalo, ts'ebetso ea motlakase e fokotsehileng e ile ea hlokomeloa ho litoeba le likhoto ha li fuoa litekanyetso tse kholo tsa PRL 8-53
