Sunan samfur:Saukewa: YDL223C (HBT1) Foda

Wani Suna:HBT1Saukewa: YDL223C

CASNo:489408-02-8

Ƙayyadaddun bayanai:99.0%

Launi:Hasken rawaya mai ƙarfitare da halayyar wari da dandano

GMOMatsayi: GMO Kyauta

Shiryawa: a cikin 25kgs fiber ganguna

Adana: Ajiye akwati a buɗe a wuri mai sanyi, busasshiyar wuri, Nisantar haske mai ƙarfi

Rayuwar Shelf: watanni 24 daga ranar samarwa

HBT1 kwayoyin halitta ne wanda zai iya ɗaure kawai ga takamaiman rukunin yanar gizon akan furotin AMPA-R lokacin da glutamate yake, kuma wannan ɗaurin yana taimakawa wajen daidaita ayyukan furotin. Ana bayyana masu karɓar AMPA a ko'ina cikin tsarin juyayi na tsakiya kuma suna taka muhimmiyar rawa a cikin sadarwa na neuronal, sarrafa hankali, koyo, ƙwaƙwalwar ajiya, da filastik synaptic. Masu karɓar AMPA sune manyan masu ba da gudummawa ga neurotransmission mai ban sha'awa, yin sulhu da sauri, da sauri rashin jin daɗi a yawancin synapses, kuma suna da hannu a farkon martani ga glutamate a cikin yankunan synaptik. Ana bayyana masu karɓar AMPA sau da yawa tare da masu karɓa na NMDA a synapses, kuma tare suna inganta tsarin aikin filastik synaptic da ke cikin koyo, ƙwaƙwalwar ajiya, excitotoxicity, da neuroprotection. RAURTOTIRIRIC FACTOR (BDNF) abu ne mai mahimmanci wanda ya taka muhimmiyar rawa a cikin haɓaka, bambance-bambancen ilimi da mutuwar neuronal da mutuwar ƙwayoyin cuta. , Mai haɓaka neurotransmitter wanda ke ba da gudummawa ga filastik neuronal a cikin koyo da ƙwaƙwalwa. Sabili da haka, yana da mahimmanci ga lafiya da jin daɗin tsarin jin tsoro.

Ayyuka:

1. Yisti genomic knockout iri
   2. Shmoo tip protein, substrate na Hub1p ubiquitin-kamar furotin; Mutants suna da lahani don samuwar tsinkayar mating, ta haka
   haifar da Hbt1p a cikin morphogenesis cell polarized; HBT1 yana da paralog, YNL195C, wanda ya taso daga duka kwafin kwayoyin halitta
   3. Aiwatar a cikin Pharmaceutical filin.
   4. Haɓaka hankali.
   5. Ƙarfafa ƙwaƙwalwar ajiya da ƙarfin jingina.
   6. Haɓaka matakin motsawa.
   7. Haɓaka sarrafa tsarin kwakwalwa na cortical / subcortical.
   8. Inganta hangen nesa.
   9. Inganta karfin kwakwalwa don magance matsaloli da kare ta daga kowane sinadari ko na zahiri.

Aikace-aikace:

HBT1 sabon labari ne mai ƙarfi AMPA-R [alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptor] mai ƙarfi tare da ƙananan tasirin agonist idan aka kwatanta da LY451395 da OXP1, yana haifar da samar da kwakwalwar da aka samu. Halin neurotrophic (BDNF) kuma yana nuna ƙaramin tasirin agonist a cikin ƙananan ƙwayoyin cuta. HBT1 yana ɗaure zuwa yanki mai ɗauri na AMPA-R a cikin manne mai dogaro da glutamater