Sunan samfur:Evodiamine

Wani Suna:Evodiamine, Isoevodiamine, (+)-Evodiamine, d-Evodiamine,Fructus Evodiae Extract

CAS No:518-17-2

Matsakaicin: 98% Min

Launi: Hasken rawaya crystalline foda

Shiryawa: a cikin 25kgs fiber ganguna

Adana: Ajiye akwati a buɗe a wuri mai sanyi, busasshiyar wuri, Nisantar haske mai ƙarfi

Rayuwar Shelf: watanni 24 daga ranar samarwa

Evodiamine wani alkaloid ne na musamman na bioactive kuma babban sinadari mai sarrafa kwayoyin halitta a cikin maganin gargajiya na kasar Sin. An samo shi a cikin berries na Evodia evodia shuka, wanda ke tsiro da farko a China da Koriya. An samo shi a cikin berries na Evodia evodia shuka, wanda ke tsiro da farko a China da Koriya. Wannan tsiro na da wadata da sinadarai iri-iri, kuma a al'adance ana amfani da ita a cikin magungunan gargajiya na kasar Sin don magance matsalolin lafiya iri-iri, da suka hada da matsalar narkewar abinci, kumburi, da zafi. Evodiamine yana aiki ta hanyar kai hari kan hanyoyin ƙwayoyin cuta daban-daban a cikin jiki. An san shi don tayar da kunna masu karɓar vanillin, wanda ke taka muhimmiyar rawa a fahimtar jin zafi da thermogenesis. Bugu da ƙari, an samo shi don yin hulɗa tare da masu karɓa na serotonin da dopamine, yana nuna cewa yana da abubuwan haɓaka yanayi.

Ayyukan Halittu: Evodiamine wani alkaloid ne wanda ya keɓe daga 'ya'yan itacen Bentham, wanda ke da ayyuka daban-daban na ilimin halitta kamar su anti-inflammatory, anti kiba, da anti-tumor. A cikin vitro: Evodiamine ya nuna cytotoxicity akan nau'ikan kwayoyin cutar kansar ɗan adam ta hanyar haifar da apoptosis. Bugu da kari, shine kwayoyin halittar dabbobi masu yawan kwayar cutar kwayoyin cuta wadanda ke haifar da ayyukan anti-tsiro ta hanyar hanyoyin da ba su dace ba kuma marasa dogaro, 31 pi3k / AKT / CASPASE, da Fas -L/. NF - κ B hanyar siginar 32 [1]. A cikin vivo: Evodiamine yana hana metabolism na dapoxetine. Idan aka kwatanta da ƙungiyar kulawa, t1 / 2, AUC (0-∞), da Tmax pharmacokinetic sigogi na dapoxetine a cikin ƙungiyar evodiamine sun karu da 63.3%, 44.8%, da 50.4%, bi da bi. Bugu da ƙari, evodiamine ya rage mahimmancin matakan t1 / 2 pharmacokinetic da AUC (0-∞) na demethylated dapoxetine [2]. Evodiamine yana hana haɓakar ƙari a cikin ƙirar H22 xenograft subcutaneous. Evodiamine yana ƙaddamar da angiogenesis na VEGF a cikin vivo.

A cikin vitro: Evodiamine yana nuna cytotoxicity akan layukan ƙwayoyin kansa na ɗan adam ta hanyar haifar da apoptosis. Bugu da kari, shine kwayoyin halittar dabbobi masu yawan kwayar cutar kwayoyin cuta wadanda ke haifar da ayyukan anti-tsiro ta hanyar hanyoyin da ba su dace ba kuma marasa dogaro, 31 pi3k / AKT / CASPASE, da Fas -L/. NF - κ B hanyar siginar 32 [1].

A cikin vivo: Evodiamine yana hana metabolism na dapoxetine. Idan aka kwatanta da ƙungiyar kulawa, t1 / 2, AUC (0-∞), da Tmax pharmacokinetic sigogi na dapoxetine a cikin ƙungiyar evodiamine sun karu da 63.3%, 44.8%, da 50.4%, bi da bi. Bugu da ƙari, evodiamine ya rage mahimmancin matakan t1 / 2 pharmacokinetic da AUC (0-∞) na demethylated dapoxetine [2]. Evodiamine yana hana haɓakar ƙari a cikin ƙirar H22 xenograft subcutaneous. Evodiamine yana ƙaddamar da angiogenesis na VEGF a cikin vivo.

AIKI:

Ayyukan anti-mai kumburi, anti-tumor, da hypoglycemic suna da wasu tasirin warkewa akan jiyya na rashin lafiya na farko da bugun jini.Yana da analgesic, saukar da hawan jini kuma yana haifar da hauhawar tasirin zafin jiki. Amfanin asibiti na wannan samfurin shine don samar da wakilai na likita don diuretics da gumi.

1. Ana amfani da cirewar Evodia don magance alamun ciwon ciki. Wadannan sun hada da tashin zuciya, amai, da gudawa. An ce yana da tasiri musamman wajen magance gudawa da safe.

2. Ana amfani da Evodia don motsa sha'awa da kuma magance alamun ciki da ke hade da rashin sha'awar abinci.

3. Evodia tsantsa kuma yana da anti-mai kumburi, anti-tumor, anti-viral, astringent, da diuretic Properties.

4. Evodiamine tare da analgesia, rage karfin jini da hawan jini da sauran tasirin magunguna.

5. Evodiamine yana da ciki, dakatar da retching, oxyrygmia sakamako da diuretic sakamako.

6.Evodiamine yana da tasirin hanawa mai ƙarfi akan li; da kuma tasiri mai mahimmanci na kwari akan ascarissuum;

7.Evodiamine shima yana iya rage mahaifa kuma yana kara matsi.

8.Besides,evodiamine kuma yana da tasiri mai kyau akan cutar Alzheimer da bugun jini.

Aikace-aikace: