Adenosine yog ib qho purine nucleoside tsim los ntawm cov molecule ntawm adenine txuas mus rau ribose qab zib molecule (ribofuranose) moiety ntawm β-N9-glycosidic daim ntawv cog lus.Adenosine tau dav pom nyob rau hauv cov xwm txheej thiab ua lub luag haujlwm tseem ceeb hauv cov txheej txheem biochemical, xws li hloov hluav taws xob - xws li adenosine triphosphate (ATP) thiab adenosine diphosphate (ADP) - nrog rau hauv cov teeb liab hloov pauv raws li cyclic adenosine monophosphate (cAMP).Nws kuj yog ib qho neuromodulator, ntseeg tau los ua lub luag haujlwm hauv kev txhawb kev pw tsaug zog thiab txo qis arousal.Adenosine kuj tseem ua lub luag haujlwm hauv kev tswj cov ntshav ntws mus rau ntau lub hauv nruab nrog cev los ntawm vasodilation.
Khoom npe:Adenosine
Lwm Lub Npe:Adenine riboside muaj
CAS Nr .: 58-61-7
Cov roj formula: C10H13N5O4
Molecular Luj: 267.24
EINECS NO.: 200-389-9
Melting point: 234-236ºC
Specification: 99% ~ 102% los ntawm HPLC
Cov tsos mob: Dawb hmoov nrog cov yam ntxwv tsw thiab saj
GMO Status: GMO Dawb
Ntim: hauv 25kgs fiber ntau nruas
Cia: Khaws lub thawv tsis qhib hauv qhov chaw txias, qhuav, Khaws kom deb ntawm lub teeb muaj zog
Lub neej txee: 24 lub hlis txij li hnub tsim khoom
Muaj nuj nqi:
-Adenosine yog endogenous nucleoside thoob plaws hauv tib neeg lub hlwb ncaj qha mus rau hauv myocardium los ntawm phosphorylation generates adenylate koom nrog hauv myocardial zog metabolism.Adenosine kuj tuaj yeem koom nrog kev nthuav dav ntawm cov hlab ntsha, ua kom cov ntshav ntws.
-Adenosine ua lub luag haujlwm physiological ntawm cov hlab plawv thiab lub cev ntau lub cev thiab cov koom haum.Adenosine yog siv nyob rau hauv lub synthesis adenosine triphosphate, adenosine (ATP), adenine, adenosine, vidarabine tseem ceeb intermediates.
Mechanism
Adenosine plays lub luag haujlwm tseem ceeb hauv biochemistry, suav nrog adenosine triphosphate (ATP) lossis adeno-bisphosphate (ADP) daim ntawv hloov hluav taws xob, lossis rau cyclic adenosine monophosphate (cAMP) rau cov teeb liab kis tau tus mob thiab lwm yam.Tsis tas li ntawd, adenosine yog ib qho inhibitory neurotransmitter (inhibitory neurotransmitter), tuaj yeem txhawb kev pw tsaug zog.
Kev tshawb fawb
Nyob rau hauv lub Kaum Ob Hlis 23 "natural – Tshuaj" (Nature Medicine) magazine, ib txoj kev tshawb fawb tshiab qhia tau hais tias ib tug compound yuav pab tau peb kom txo tau lub hlwb ntawm pw tsaug zog thiab lwm yam paj hlwb kab mob Parkinson tus kab mob sib sib zog nqus hlwb stimulation ntawm kev vam meej yog ib qho tseem ceeb.Txoj kev tshawb no qhia tau hais tias: lub hlwb pw tsaug zog tuaj yeem ua rau muaj kev sib xyaw - Adenosine yog lub hlwb sib sib zog nqus (DBS) cuam tshuam ntawm tus yuam sij.Cov thev naus laus zis rau kev kho mob Parkinson tus kab mob thiab cov neeg mob uas muaj kev tshee hnyav, txoj kev no kuj tau sim rau kev kho mob ntawm kev nyuaj siab loj.