Beta-nicotinamide Mononucleotide (NMN), ib yam khoom ntawm NAMPT cov tshuaj tiv thaiv thiab ib qho tseem ceeb NAD + nruab nrab, ameliorates qabzib intolerance los ntawm restores NAD + qib hauv HFD-induced T2D nas.NMN kuj tseem txhim kho lub siab insulin rhiab heev thiab rov kho cov noob qhia ntsig txog oxidative kev nyuaj siab, inflammatory teb, thiab circadian atherosclerosis, ib nrab ntawm SIRT1 ua kom.NMN yog siv los kawm txog kev sib khi motifs hauv RNA aptamers thiab ribozyme activation txheej txheem uas muaj β-nicotinamide mononucleotide (Beta-NMN)-activated RNA fragments.
Nicotinamide mononucleotide ("NMN" thiab "β-NMN") yog nucleotide muab los ntawm ribose thiab nicotinamide.Niacinamide (nicotinamide,) yog ib daim ntawv ntawm vitamin B3 (niacin.) Raws li biochemical precursor ntawm NAD +, nws yuav pab tau rau kev tiv thaiv ntawm pellagra.
Nws daim ntawv tsis tseem ceeb, niacin, muaj nyob hauv ntau yam khoom noj khoom haus: Peanuts, Mushrooms (portobello, grilled), Avocados, Ntsuab Peas (tshiab), thiab qee yam ntses thiab tsiaj txhu.
Hauv kev tshawb fawb [ntawm nas], NMN tau pom tias rov qab muaj hnub nyoog txog kev ua haujlwm ntawm cov hlab ntsha los ntawm kev txo qis oxidative kev nyuaj siab.
Lub npe: Beta-Nicotinamide Mononucleotide
CAS: 1094-61-7 Nr
Khoom npe: Beta-Nicotinamide Mononucleotide; NMN
Lwm lub npe: β-D-NMN; BETA-NMN; beta-D-NMN; NMN zwitterion; Nicotinamide Ribotide; Nicotinamide nucleotide; Nicotimide mononucleotide; Nicotinamide mononucleotide
CAS: 1094-61-7
Cov mis mos molecular: C11H15N2O8P
Molecular Luj: 334.22
Purity: 98%
Cia kub: 2-8 ° C
Cov tsos mob: Dawb hmoov
Siv: anti-aging
Muaj nuj nqi:
1.Nicotinamide mononucleotide hauv tib neeg lub hlwb ua lub luag haujlwm tseem ceeb hauv kev tsim hluav taws xob, nws koom nrog hauv intracellular NAD (nicotinamide adenine dinucleotide, cell zog conversion tseem ceeb coenzyme) synthesis, siv los tiv thaiv kev laus, poob ntshav qab zib thiab lwm yam khoom kho mob.
2. Nicotinamide Mononucleotide yog dej-soluble vitamin, Cov khoom yog dawb crystalline hmoov, tsis muaj ntxhiab los yog ze li ntawm odorless, iab nyob rau hauv saj, dawb soluble nyob rau hauv dej los yog ethanol, dissolvable nyob rau hauv glycerin.
3.Nicotinamide Mononucleotide yog ib qho yooj yim kom nqus tau qhov ncauj, thiab tuaj yeem nthuav dav hauv lub cev, cov metabolites ntau dhau los yog cov qauv tawm sai sai ntawm cov zis.Nicotinamide yog ib feem ntawm coenzyme I thiab coenzyme II, plays lub luag hauj lwm ntawm hydrogen xa hauv cov kab mob oxidation ua pa, tuaj yeem txhawb cov txheej txheem oxidation lom thiab cov ntaub so ntswg metabolism, tswj cov nqaij mos (tshwj xeeb tshaj yog ntawm daim tawv nqaij, plab hnyuv thiab lub paj hlwb) kev ncaj ncees muaj lub luag haujlwm tseem ceeb. .
Tsis tas li ntawd, nicotinamide muaj kev tiv thaiv thiab kev kho mob ntawm lub plawv block, sinus node muaj nuj nqi thiab anti-ceev sim arrhythmias, nicotinamide tuaj yeem txhim kho lub plawv dhia thiab atrioventricular block los ntawm verapamil.
