| Aha kemịkalụ: | 10-Deacetylbaccatin III |
Nọmba CAS: | 32981-86-5 |
| Ụdị okwu: | 10-Desacetylbaccatin III; 10β-Deacetylbaccatin III; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy) -1,2a,3,4,4a,6,9,10,11,12,12a,12b-dod ecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca [3,4] benz [1,2-b] oxet-5-otu; 7,11-Methano-5H-cyclodeca[3,4] benz[1,2-b]oxet-5-otu, 12b- (acetyloxy) -12- (benzoyloxy) -1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-; (Docetaxel USP adịghị ọcha);10-Deacetylbaccatin III; 10-Deacetyl baccatin; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-1,2a,3,4,4a,6,9,10,11,12,12a, 12b-Dodecahydro-4,6,9,11,12,12b-hexahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca [3,4] benz [1,2-b] oxet-5-otu 12b-acetate, (USPatete, 12-); |
| Ụdị molekụla: | C29H36O10 |
| Ọdịdị: | Ọcha siri ike |
| Mol. Arọ: | 544.6 |
| Nchekwa: | Igwe nju oyi 2-8 Celsius |
Ndepụta Okwu: Ihe ọkụkụ sitere na API Intermediate, CAS32981-86-5| Asambodo GMP, COA nyere
Kedu ihe bụ 10-Deacetylbaccatin III10-DAB)?
10-Deacetylbaccatin III (C29H36O10) bụ diterpenoid bioactive sitere na agịga na ogbugbo.Taxisumu (osisi yew). Dị ka isi mmalite na ọkara njikọ nke paclitaxel, docetaxel, na ndị ọrụ chemotherapeutic ndị ọzọ dabeere na taxed, 10-DAB na-ejikarị eme ihe na R&D ọgwụ na mmepụta ọgwụ oncology.
Nkọwapụta igodo & atụmatụ
- Dị ọcha: ≥98% (HPLC-UV kwadoro, COA dị)
- Ọdịdị: White na-acha ọcha kristal ntụ ntụ
- Solubility: Soluble na methanol, ethanol, DMSO; ubé soluble na mmiri
- Nchekwa: Stable na -20C n'ime akpa ikuku, na-echebe site na ìhè
- Isi Iyi Osisi: A na-egbute ya na-adịgide adịgideTaxus wallichiana(Himalayan yew)
Ngwa nke 10-DAB
- Njikọ ọgwụ mgbochi ọrịa kansa
- Ihe etiti dị oke mkpa maka mmepụta ọkara synthetic nke paclitaxel (Taxol®) na docetaxel (Taxotere®).
- A na-eji ya na R&D maka usoro usoro taxedo ọhụrụ na-ezubere maka ọrịa cancer na-eguzogide ọgwụ.
- Nnyocha biochemical
- Ọmụmụ usoro tubulin polymerization na ntinye apoptosis.
- Ụkpụrụ ntụaka maka kemistri nyocha na njikwa mma.
- Eke Ngwaahịa Mwepụta
- Usoro mmịpụta mkpụrụ dị elu dabara na ụkpụrụ kemistri akwụkwọ ndụ akwụkwọ ndụ.
Gịnị kpatara isi mmalite 10-DAB sitere n'aka anyị?
✅ Akwadoro ogo:
- Asambodo nyocha nke Batch-kpọmkwem (COA) nwere data HPLC, MS, NMR.
- Dabara na ntuziaka USP, EP, na ICH Q7 GMP.
✅ Isi mmalite na-adịgide adịgide:
- A na-egbute n'ụzọ ziri ezi site na ugbo Taxus akọpụtara (CITES Ihe Okike II kwadoro).
✅ Global Logistics:
- Mbupu yinye oyi na-enweghị ntụpọ na mpaghara USA, EU na APAC.
- Nkwakọ ngwaahịa nwere ike ịhazi ya (1g ruo 1kg, vial amber glass na desiccant).
Nkwado nka na ụzụ & akwụkwọ
- MSDS efu (akwụkwọ data nchekwa ihe) yana data kwụsie ike mgbe achọrọ ya.
- Ngwakọta omenala na ọnụ ahịa buru ibu dị maka ndị mmekọ OEM.
- Nkwado usoro iwu raara onwe ya nye maka ntinye akwụkwọ IND/NDA.
Nchekwa & nnabata
- Nọmba CAS: 32981-86-5
- Koodu ihe egwu: Ejikwa PPE (gloves, goggles) - adịghị ize ndụ maka ojiji ọkachamara.
- Ọnọdụ nchịkwa: REACH debara aha; DMF dị maka ndị ahịa ọgwụ.
Ajụjụ maka 10-DAB
Ajụjụ: Enwere ike iji 10-DAB mee ihe ozugbo na ọmụmụ omenala cell?
A: Mba. Ọ chọrọ mgbanwe kemịkalụ (dịka ọmụmaatụ, mgbakwunye agbụ akụkụ) ka ọ bụrụ taxix bioactive.
Ajụjụ: Gịnị bụ oge ụzọ maka iwu 500g?
A: Standard mmepụta oge: 2-3 izu. Mbupu ngwa ngwa dị.
Ajụjụ: Ị na-enye usoro nhazi ụtụ isi?
A: Ee! Akwụkwọ ọcha dị maka ndị ahịa ruru eru.
Nkọwa:
Isi mmalite 98% HPLC-ọkwa 10-Deacetylbaccatin III (CAS 32981-86-5) - Mwepụta Taxus kwadoro GMP maka njikọ paclitaxel. Iwu nnukwu, COA/MSDS, yana nkwado usoro gụnyere.
- Okwu:
- Nke mbụ: "10-Deacetylbaccatin III soplaya", "Elu ịdị ọcha 10-DAB", "Paclitaxel precursor"
- Ogologo ọdụ: "ọnụahịa CAS 32981-86-5", "Mwepụta taxus maka nyocha ọrịa kansa", "GMP 10-DAB"
- Okwu:
- "Taxane etiti", "paclitaxel semi-synthetic", "C29H36O10", "yew osisi ogige"
